Titelia

Fund shareholders of IONIS PHARMACEUTICALS INC

ISIN US4622221004 · United States · LEI 549300SI4ZGLG0BLUZ92

Fund shareholders
428
Of which ETFs
99 329 other funds
Value held
≈ 6.7B $ 6.6B $ · 346.9M SEK · 4M €
Share of capital
54.4 % of 166.2M shares on Jul 23, 2026

428 funds hold this company. This table lists the 423 that declare it in a regulatory filing. The other 5 publish their holdings in their own reports. The “Fund reports” tab lists them, with their weight.

FundSharesValueWeight in fundShare of capital
Fidelity Growth Company Fund Fidelity Mt. Vernon Street Trust 8,471,732648.1M $0.66 %5.10 %as of May 31, 2026 ↗
Growth Fund of America Growth Fund of America 7,668,655586.7M $0.16 %4.61 %as of May 31, 2026 ↗
VANGUARD HEALTH CARE FUND VANGUARD SPECIALIZED FUNDS 6,212,640321.6M $0.84 %3.74 %as of Jul 31, 2026 ↗
SMALLCAP World Fund Inc SMALLCAP World Fund Inc 5,259,919417.1M $0.44 %3.17 %as of Jun 30, 2026 ↗
VANGUARD TOTAL STOCK MARKET INDEX FUND VANGUARD INDEX FUNDS 4,989,044395.6M $0.02 %3.00 %as of Jun 30, 2026 ↗
New Economy Fund New Economy Fund 4,868,802372.5M $0.72 %2.93 %as of May 31, 2026 ↗
VANGUARD SMALL-CAP INDEX FUND VANGUARD INDEX FUNDS 3,597,995285.3M $0.15 %2.17 %as of Jun 30, 2026 ↗
Fidelity Growth Company K6 Fund Fidelity Mt. Vernon Street Trust 2,348,458179.7M $0.65 %1.41 %as of May 31, 2026 ↗
Fidelity Series Growth Company Fund Fidelity Mt. Vernon Street Trust 2,090,022159.9M $0.65 %1.26 %as of May 31, 2026 ↗
VANGUARD SMALL-CAP GROWTH INDEX FUND VANGUARD INDEX FUNDS 2,075,497164.6M $0.35 %1.25 %as of Jun 30, 2026 ↗
T. Rowe Price Mid-Cap Growth Fund, Inc. T. ROWE PRICE MID-CAP GROWTH FUND, INC. 1,998,674158.5M $0.69 %1.20 %as of Jun 30, 2026 ↗
VANGUARD EXTENDED MARKET INDEX FUND VANGUARD INDEX FUNDS 1,894,588150.2M $0.15 %1.14 %as of Jun 30, 2026 ↗
Tweedy, Browne International Value Fund Tweedy, Browne Fund Inc. 1,743,125138.2M $3.25 %1.05 %as of Jun 30, 2026 ↗
Growth Fund AMERICAN FUNDS INSURANCE SERIES 1,674,900132.8M $0.23 %1.01 %as of Jun 30, 2026 ↗
VANGUARD EXPLORER FUND VANGUARD EXPLORER FUND 1,465,67775.9M $0.34 %0.88 %as of Jul 31, 2026 ↗
State Street(R) SPDR(R) S&P(R) Biotech ETF SPDR SERIES TRUST 1,358,012107.7M $1.00 %0.82 %as of Jun 30, 2026 ↗
Capital Group Growth ETF Capital Group Growth ETF 1,150,28488M $0.36 %0.69 %as of May 31, 2026 ↗
iShares Biotechnology ETF iShares Trust 1,148,49691.1M $1.00 %0.69 %as of Jun 30, 2026 ↗
JPMorgan Mid Cap Growth Fund JPMorgan Trust II 1,123,20989.1M $0.67 %0.68 %as of Jun 30, 2026 ↗
iShares Russell Mid-Cap Growth ETF iShares Trust 916,59272.7M $0.34 %0.55 %as of Jun 30, 2026 ↗
Fidelity Extended Market Index Fund Fidelity Concord Street Trust 833,61363.8M $0.15 %0.50 %as of May 31, 2026 ↗
Franklin Dynatech Fund Franklin Custodian Funds 800,00063.4M $0.21 %0.48 %as of Jun 30, 2026 ↗
Schwab U.S. Small-Cap ETF SCHWAB STRATEGIC TRUST 778,64459.6M $0.26 %0.47 %as of May 31, 2026 ↗
iShares Russell Mid-Cap ETF iShares Trust 676,08253.6M $0.09 %0.41 %as of Jun 30, 2026 ↗
Select Fund American Century Mutual Funds, Inc. 664,10034.4M $0.56 %0.40 %as of Jul 31, 2026 ↗
Fidelity Mid Cap Index Fund Fidelity Salem Street Trust 622,86532.2M $0.06 %0.37 %as of Jul 31, 2026 ↗
iShares Russell 1000 Growth ETF iShares Trust 592,54047M $0.04 %0.36 %as of Jun 30, 2026 ↗
Eventide Healthcare & Life Sciences Fund MUTUAL FUND SERIES TRUST 575,00045.6M $2.55 %0.35 %as of Jun 30, 2026 ↗
T. Rowe Price New Horizons Fund, Inc. T. ROWE PRICE NEW HORIZONS FUND, INC. 559,72344.4M $0.30 %0.34 %as of Jun 30, 2026 ↗
Nomura Mid Cap Growth Fund IVY FUNDS 546,71243.3M $1.45 %0.33 %as of Jun 30, 2026 ↗
ARK Genomic Revolution ETF ARK ETF Trust 531,63327.5M $1.77 %0.32 %as of Jul 31, 2026 ↗
Nomura Science and Technology Fund IVY FUNDS 529,49842M $0.48 %0.32 %as of Jun 30, 2026 ↗
Select Biotechnology Portfolio Fidelity Select Portfolios 476,37736.4M $0.69 %0.29 %as of May 31, 2026 ↗
VANGUARD HEALTH CARE INDEX FUND VANGUARD WORLD FUND 462,32135.4M $0.19 %0.28 %as of May 31, 2026 ↗
Schwab U.S. Mid-Cap ETF SCHWAB STRATEGIC TRUST 438,44733.5M $0.23 %0.26 %as of May 31, 2026 ↗
T. Rowe Price Health Sciences Fund, Inc. T. ROWE PRICE HEALTH SCIENCES FUND, INC. 433,92334.4M $0.29 %0.26 %as of Jun 30, 2026 ↗
Artisan International Small-Mid Fund Artisan Partners Funds Inc. 425,36633.7M $1.33 %0.26 %as of Jun 30, 2026 ↗
Capital Group U.S. Small and Mid Cap ETF Capital Group Equity ETF Trust I 414,65331.7M $1.14 %0.25 %as of May 31, 2026 ↗
Harbor Small Cap Growth Fund HARBOR FUNDS 405,58021M $0.79 %0.24 %as of Jul 31, 2026 ↗
Global Growth Fund AMERICAN FUNDS INSURANCE SERIES 388,00030.8M $0.29 %0.23 %as of Jun 30, 2026 ↗
VANGUARD STRATEGIC EQUITY FUND VANGUARD HORIZON FUNDS 379,25730.1M $0.25 %0.23 %as of Jun 30, 2026 ↗
Artisan Small Cap Fund Artisan Partners Funds Inc. 357,73828.4M $2.96 %0.22 %as of Jun 30, 2026 ↗
Small Cap Growth Fund American Century Mutual Funds, Inc. 334,67817.3M $0.31 %0.20 %as of Jul 31, 2026 ↗
Fidelity Total Market Index Fund Fidelity Concord Street Trust 308,22623.6M $0.02 %0.19 %as of May 31, 2026 ↗
JNL/JPMorgan MidCap Growth Fund JNL Series Trust 306,86124.3M $0.68 %0.18 %as of Jun 30, 2026 ↗
Neuberger Mid Cap Growth Fund NEUBERGER BERMAN EQUITY FUNDS 294,67122.5M $1.00 %0.18 %as of May 31, 2026 ↗
College Retirement Equities Fund - Total Global Stock Account College Retirement Equities Fund 293,37223.3M $0.02 %0.18 %as of Jun 30, 2026 ↗
Strategic Advisers U.S. Total Stock Fund Fidelity Rutland Square Trust II 267,91620.5M $0.02 %0.16 %as of May 31, 2026 ↗
MFS New Discovery Fund MFS SERIES TRUST I 262,55320.1M $0.94 %0.16 %as of May 31, 2026 ↗
iShares U.S. Equity Factor Rotation Active ETF BlackRock ETF Trust 257,11813.3M $0.03 %0.15 %as of Jul 31, 2026 ↗
T. Rowe Price Integrated U.S. Small-Cap Growth Equity Fund T. ROWE PRICE INTEGRATED EQUITY FUNDS, INC. 253,42520.1M $0.20 %0.15 %as of Jun 30, 2026 ↗
Artisan Mid Cap Fund Artisan Partners Funds Inc. 250,17319.8M $0.62 %0.15 %as of Jun 30, 2026 ↗
Fidelity Series Total Market Index Fund Fidelity Concord Street Trust 247,64218.9M $0.02 %0.15 %as of May 31, 2026 ↗
VANGUARD RUSSELL 1000 GROWTH INDEX FUND VANGUARD SCOTTSDALE FUNDS 242,72818.6M $0.03 %0.15 %as of May 31, 2026 ↗
T. Rowe Price Institutional Mid-Cap Equity Growth Fund T. Rowe Price Equity Funds, Inc. 227,88618.1M $0.70 %0.14 %as of Jun 30, 2026 ↗
AMG TimesSquare Mid Cap Growth Fund AMG Funds 220,20017.5M $1.02 %0.13 %as of Jun 30, 2026 ↗
T. Rowe Price Diversified Mid-Cap Growth Fund, Inc. T. ROWE PRICE DIVERSIFIED MID-CAP GROWTH FUND, INC. 218,82617.4M $0.35 %0.13 %as of Jun 30, 2026 ↗
iShares Core S&P Total U.S. Stock Market ETF iShares Trust 216,76817.2M $0.02 %0.13 %as of Jun 30, 2026 ↗
Bridge Builder Small/Mid Cap Growth Fund Bridge Builder Trust 216,60517.2M $0.15 %0.13 %as of Jun 30, 2026 ↗
Small Cap Core Fund John Hancock Investment Trust 215,58711.2M $0.57 %0.13 %as of Jul 31, 2026 ↗
Invesco Main Street Mid Cap Fund AIM Growth Series (Invesco Growth Series) 213,72516.9M $0.65 %0.13 %as of Jun 30, 2026 ↗
JNL/T. Rowe Price Mid-Cap Growth Fund JNL Series Trust 212,81016.9M $0.39 %0.13 %as of Jun 30, 2026 ↗
Franklin Biotechnology Discovery Fund Franklin Strategic Series 209,42310.8M $0.94 %0.13 %as of Jul 31, 2026 ↗
VANGUARD STRATEGIC SMALL-CAP EQUITY FUND VANGUARD HORIZON FUNDS 206,93316.4M $0.52 %0.12 %as of Jun 30, 2026 ↗
Fidelity Large Cap Growth Index Fund Fidelity Salem Street Trust 204,29210.6M $0.03 %0.12 %as of Jul 31, 2026 ↗
MFS New Discovery Value Fund MFS SERIES TRUST XIII 185,92614.2M $0.57 %0.11 %as of May 31, 2026 ↗
Empower T. Rowe Price Mid Cap Growth Fund EMPOWER FUNDS, INC. 179,64814.2M $0.69 %0.11 %as of Jun 30, 2026 ↗
First Trust Health Care AlphaDEX Fund First Trust Exchange-Traded AlphaDEX Fund 179,5749.3M $0.89 %0.11 %as of Jul 31, 2026 ↗
Goldman Sachs Small/Mid Cap Growth Fund Goldman Sachs Trust 179,01413.7M $1.09 %0.11 %as of May 31, 2026 ↗
BlackRock Health Sciences Opportunities Portfolio BlackRock Funds 170,00813M $0.22 %0.10 %as of May 29, 2026 ↗
Tweedy, Browne Value Fund Tweedy, Browne Fund Inc. 169,63513.5M $2.85 %0.10 %as of Jun 30, 2026 ↗
Franklin Small-Mid Cap Growth Fund Franklin Strategic Series 167,0608.6M $0.25 %0.10 %as of Jul 31, 2026 ↗
Fidelity Mid Cap Growth Index Fund Fidelity Salem Street Trust 165,87413.2M $0.33 %0.10 %as of Jun 30, 2026 ↗
MassMutual Mid Cap Growth Fund MASSMUTUAL SELECT FUNDS 165,39513.1M $0.52 %0.10 %as of Jun 30, 2026 ↗
VANGUARD TAX-MANAGED CAPITAL APPRECIATION FUND VANGUARD TAX-MANAGED FUNDS 164,67113.1M $0.04 %0.10 %as of Jun 30, 2026 ↗
SMALL COMPANY GROWTH PORTFOLIO VANGUARD VARIABLE INSURANCE FUNDS 164,18713M $0.77 %0.10 %as of Jun 30, 2026 ↗
JPMorgan Large Cap Value Fund JPMorgan Trust II 163,18812.9M $0.25 %0.10 %as of Jun 30, 2026 ↗
JPMorgan Mid Cap Equity Fund JPMorgan Trust I 160,20412.7M $0.20 %0.10 %as of Jun 30, 2026 ↗
JNL/Invesco Small Cap Growth Fund JNL Series Trust 154,61612.3M $0.60 %0.09 %as of Jun 30, 2026 ↗
Handelsbanken Hälsovård Tema Handelsbanken Fonder AB 154,000110.2M SEK0.50 %0.09 %as of Mar 31, 2026 ↗
Nuveen ESG Small-Cap ETF NuShares ETF Trust 151,5357.8M $0.61 %0.09 %as of Jul 31, 2026 ↗
VANGUARD TOTAL WORLD STOCK INDEX FUND VANGUARD INTERNATIONAL EQUITY INDEX FUNDS 149,7317.8M $0.01 %0.09 %as of Jul 31, 2026 ↗
SMALLCAP World Fund AMERICAN FUNDS INSURANCE SERIES 143,35711.4M $0.44 %0.09 %as of Jun 30, 2026 ↗
Invesco Small Cap Growth Fund AIM Growth Series (Invesco Growth Series) 142,19911.3M $0.61 %0.09 %as of Jun 30, 2026 ↗
iShares U.S. Small-Cap Equity Factor ETF iShares Trust 132,3246.9M $0.17 %0.08 %as of Jul 31, 2026 ↗
Nuveen Equity Index Fund TIAA-CREF Funds 129,8906.7M $0.01 %0.08 %as of Jul 31, 2026 ↗
T. Rowe Price Small-Mid Cap ETF T. Rowe Price Exchange-Traded Funds, Inc. 118,3989.4M $0.35 %0.07 %as of Jun 30, 2026 ↗
iShares Russell 1000 ETF iShares Trust 114,4149.1M $0.02 %0.07 %as of Jun 30, 2026 ↗
SEB Läkemedelsfond SEB Funds AB 114,33481.8M SEK0.51 %0.07 %as of Mar 31, 2026 ↗
Goldman Sachs Mid Cap Growth Fund Goldman Sachs Trust 112,2168.6M $0.88 %0.07 %as of May 31, 2026 ↗
Invesco RAFI US 1500 Small-Mid ETF Invesco Exchange-Traded Fund Trust 110,7615.7M $0.21 %0.07 %as of Jul 31, 2026 ↗
JPMorgan Active Value ETF J.P. Morgan Exchange-Traded Fund Trust 105,5208.4M $0.13 %0.06 %as of Jun 30, 2026 ↗
THE HARTFORD HEALTHCARE FUND HARTFORD MUTUAL FUNDS, INC 104,0435.4M $0.70 %0.06 %as of Jul 31, 2026 ↗
Schwab Total Stock Market Index Fund SCHWAB CAPITAL TRUST 102,3105.3M $0.01 %0.06 %as of Jul 31, 2026 ↗
Fidelity Nasdaq Composite Index Fund Fidelity Concord Street Trust 99,1777.6M $0.03 %0.06 %as of May 31, 2026 ↗
T. Rowe Price Mid Cap Growth Portfolio Brighthouse Funds Trust I 99,0907.9M $0.70 %0.06 %as of Jun 30, 2026 ↗
Large Cap Index Master Portfolio Master Investment Portfolio 97,0357.7M $0.02 %0.06 %as of Jun 30, 2026 ↗
Schwab U.S. Broad Market ETF SCHWAB STRATEGIC TRUST 96,6737.4M $0.02 %0.06 %as of May 31, 2026 ↗
iShares U.S. Healthcare ETF iShares Trust 96,5525M $0.14 %0.06 %as of Jul 31, 2026 ↗
Mid Cap Growth Stock Portfolio NORTHWESTERN MUTUAL SERIES FUND INC 95,2707.6M $0.68 %0.06 %as of Jun 30, 2026 ↗

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Funds that publish their own holdings

FundWeight in fund
Edmond de Rothschild Fund - Healthcare Edmond de Rothschild Asset Management (Luxembourg) 2.90 %as of Mar 31, 2026 ↗
BNP Paribas Funds Health Care Innovators BNP Paribas Asset Management Luxembourg 2.45 %as of Dec 31, 2025 ↗
Pictet - Biotech Pictet Asset Management (Europe) S.A. 2.18 %as of Sep 30, 2025 ↗
BNP Paribas Funds US Mid Cap BNP Paribas Asset Management Luxembourg 1.42 %as of Dec 31, 2025 ↗
BNP Paribas Funds US Small Cap BNP Paribas Asset Management Luxembourg 0.84 %as of Dec 31, 2025 ↗

The funds most exposed to it

The weight is the share of a fund's net assets. The holders table ranks funds by number of shares. This one ranks them by the weight of the company in each fund.

FundWeight in fund
A&P LIFESCIENCE FUND, FI WELZIA MANAGEMENT, SGIIC, S.A. 4.58 %as of Dec 31, 2025 ↗
Horizon Kinetics Medical ETF Listed Funds Trust 4.53 %as of Jun 30, 2026 ↗
HealthInvest Small & Mid Cap Healthcare Atle Fund Management AB 3.98 %as of Mar 31, 2026 ↗
GESTION BOUTIQUE VI, FI GESTION BOUTIQUE VI / KALDI ANDBANK WEALTH MANAGEMENT, SGIIC, S.A.U. 3.68 %as of Dec 31, 2025 ↗
Tweedy, Browne International Value Fund Tweedy, Browne Fund Inc. 3.25 %as of Jun 30, 2026 ↗
Artisan Small Cap Fund Artisan Partners Funds Inc. 2.96 %as of Jun 30, 2026 ↗
Edmond de Rothschild Fund - Healthcare Edmond de Rothschild Asset Management (Luxembourg) 2.90 %as of Mar 31, 2026 ↗
Tweedy, Browne Value Fund Tweedy, Browne Fund Inc. 2.85 %as of Jun 30, 2026 ↗
AlphaCentric Life Sciences and Healthcare Fund MUTUAL FUND SERIES TRUST 2.62 %as of Jun 30, 2026 ↗
Eventide Healthcare & Life Sciences Fund MUTUAL FUND SERIES TRUST 2.55 %as of Jun 30, 2026 ↗

Quarter after quarter

Each row is one quarter of SEC filings, newest first. The change compares each quarter with the one before.

QuarterShareholdersChangeSharesChange
2026Q3414-889,859,743+5.2 %
2026Q2422+2985,444,539+5.7 %
2026Q1393+4580,814,443+5.3 %
2025Q4348+6276,715,982-3.1 %
2025Q3286+1279,201,702-1.0 %
2025Q2274-1279,971,398+0.1 %
2025Q1286-1779,920,146+7.6 %
2024Q4303+474,303,125+10.4 %
2024Q3299-1067,280,894+3.7 %
2024Q2309+1064,888,088+5.0 %
2024Q1299+1561,777,585-4.9 %
2023Q428464,944,400

Institutional managers

483 managers declare this company to the SEC (Form 13F). The table shows the 25 largest.

ManagerSharesValue
FMR LLC24,556,6371.8B $as of Mar 31, 2026
Capital World Investors21,186,3691.6B $as of Mar 31, 2026
BlackRock, Inc.10,442,476784.1M $as of Mar 31, 2026
WELLINGTON MANAGEMENT GROUP LLP6,391,816480M $as of Mar 31, 2026
T. Rowe Price Investment Management, Inc.6,159,027462.5K $as of Mar 31, 2026
TWO SIGMA INVESTMENTS, LP5,857,629439.8M $as of Mar 31, 2026
STATE STREET CORP3,995,564300M $as of Mar 31, 2026
GEODE CAPITAL MANAGEMENT, LLC3,984,332305.2M $as of Mar 31, 2026
ROYAL BANK OF CANADA3,801,815285.5M $as of Mar 31, 2026
PRICE T ROWE ASSOCIATES INC /MD/3,025,251227.2K $as of Mar 31, 2026
JPMORGAN CHASE & CO2,363,567171.4M $as of Mar 31, 2026
Tweedy, Browne Co LLC2,275,625170.9M $as of Mar 31, 2026
Artisan Partners Limited Partnership2,058,308154.6M $as of Mar 31, 2026
BAKER BROS. ADVISORS LP2,047,727153.8M $as of Mar 31, 2026
DEERFIELD MANAGEMENT COMPANY, L.P.1,979,669148.7M $as of Mar 31, 2026
Deep Track Capital, LP1,950,000146.4M $as of Mar 31, 2026
Bellevue Group AG1,818,665136.6M $as of Mar 31, 2026
GOLDMAN SACHS GROUP INC1,699,847127.6M $as of Mar 31, 2026
AMERICAN CENTURY COMPANIES INC1,663,803124.9M $as of Mar 31, 2026
CHARLES SCHWAB INVESTMENT MANAGEMENT INC1,583,266118.9M $as of Mar 31, 2026
FRANKLIN RESOURCES INC1,575,023118.3M $as of Mar 31, 2026
UBS AM, a distinct business unit of UBS ASSET MANAGEMENT AMERICAS LLC1,475,632110.8M $as of Mar 31, 2026
Pictet Asset Management Holding SA1,434,995107.1M $as of Mar 31, 2026
SUMMIT PARTNERS PUBLIC ASSET MANAGEMENT, LLC1,404,033105.4M $as of Mar 31, 2026
Invesco Ltd.1,277,35895.9M $as of Mar 31, 2026

Funds holding the debt of IONIS PHARMACEUTICALS INC

50 funds declare 63 bond lines of this company. The table shows the 25 largest holdings. The amount is the one the fund files. It is not a share of the debt, because no regulator publishes the amount outstanding in open access.

FundBond linesValue
iShares Convertible Bond ETF229.5M $as of Jul 31, 2026
State Street(R) SPDR(R) Bloomberg Convertible Securities ETF225.6M $as of Jun 30, 2026
Virtus Income & Growth Fund219.2M $as of Jun 30, 2026
Virtus Convertible Fund218M $as of Jun 30, 2026
Columbia Convertible Securities Fund117.8M $as of May 31, 2026
NYLIM MacKay Convertible Fund115.7M $as of Jul 31, 2026
Calamos Market Neutral Income Fund115.3M $as of Jul 31, 2026
NYLIM VP MacKay Convertible Portfolio113.2M $as of Jun 30, 2026
Lord Abbett Convertible Fund110.6M $as of May 31, 2026
Fidelity Convertible Securities Fund29.1M $as of May 31, 2026
Calamos Convertible Fund18.2M $as of Jul 31, 2026
Invesco Convertible Securities Fund16.6M $as of Jun 30, 2026
Fidelity Strategic Dividend and Income Fund24M $as of May 31, 2026
THE HARTFORD STRATEGIC INCOME FUND23.3M $as of Jul 31, 2026
Putnam Convertible Securities Fund12.4M $as of Jul 31, 2026
Global Opportunities Portfolio12.4M $as of Jul 31, 2026
American Beacon SSI Alternative Income Fund12.2M $as of Jun 30, 2026
Voya Global Income & Growth Fund12.2M $as of May 31, 2026
THE HARTFORD BALANCED INCOME FUND11.4M $as of Jul 31, 2026
Calamos Global Convertible Fund11.4M $as of Jul 31, 2026
Calvert Bond Fund11.4M $as of Jun 30, 2026
High Yield Bond Fund11.2M $as of May 31, 2026
Empower High Yield Bond Fund11.2M $as of Jun 30, 2026
Hartford Strategic Income ETF21M $as of Jul 31, 2026
Eaton Vance Total Return Bond Fund1960.8K $as of Jun 30, 2026
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Titelia. "Fund shareholders of IONIS PHARMACEUTICALS INC". https://titelia.com/en/stocks/ionis-pharmaceuticals-inc-US4622221004