Holdings of iShares Biotechnology ETF
ISIN US4642875565
iShares Trust · Original filing · Compare with another fund · Report an error
- Net assets
- 9.1B $ including 9.1B $ in equities, 99.9 %
- Positions
- 239 in 20 countries
- Top ten
- 44.7 % of net assets
- Filed on
- Jun 30, 2026
Portfolio shape
Positions
| Rank | Company | Shares | Value | Weight |
|---|---|---|---|---|
| 1 | Vertex Pharmaceuticals Inc | 1,478,300 | 734.3M $ | 8.08 % |
| 2 | Amgen Inc | 1,964,435 | 711.4M $ | 7.83 % |
| 3 | Gilead Sciences Inc | 4,921,526 | 621.8M $ | 6.84 % |
| 4 | Regeneron Pharmaceuticals Inc | 715,060 | 445.9M $ | 4.91 % |
| 5 | Argenx SE | 368,177 | 341.6M $ | 3.76 % |
| 6 | ALNYLAM PHARMACEUTICALS INC | 942,174 | 283.6M $ | 3.12 % |
| 7 | NATERA INC | 967,683 | 262.7M $ | 2.89 % |
| 8 | REVOLUTION MEDICINES INC | 1,349,118 | 252.7M $ | 2.78 % |
| 9 | Biogen Inc | 1,037,164 | 224.1M $ | 2.47 % |
| 10 | Illumina Inc | 1,069,358 | 188M $ | 2.07 % |
| 11 | MODERNA INC | 2,574,707 | 180.3M $ | 1.98 % |
| 12 | Insmed Inc | 1,521,319 | 162.2M $ | 1.78 % |
| 13 | BEONE MEDICINES LTD | 564,180 | 160.8M $ | 1.77 % |
| 14 | Incyte Corp | 1,402,629 | 159M $ | 1.75 % |
| 15 | United Therapeutics Corp | 290,800 | 157.6M $ | 1.73 % |
| 16 | Roivant Sciences Ltd | 3,661,689 | 129.6M $ | 1.43 % |
| 17 | Neurocrine Biosciences Inc | 700,051 | 118M $ | 1.30 % |
| 18 | Ascendis Pharma A/S | 438,135 | 116.9M $ | 1.29 % |
| 19 | Genmab A/S | 3,701,095 | 101.7M $ | 1.12 % |
| 20 | Exelixis Inc | 1,726,035 | 93.9M $ | 1.03 % |
| 21 | IONIS PHARMACEUTICALS INC | 1,148,496 | 91.1M $ | 1.00 % |
| 22 | Bridgebio Pharma Inc | 1,198,062 | 89.2M $ | 0.98 % |
| 23 | Medpace Holdings Inc | 163,042 | 86.3M $ | 0.95 % |
| 24 | Madrigal Pharmaceuticals Inc | 153,736 | 82.5M $ | 0.91 % |
| 25 | Bio-Techne Corp | 1,105,421 | 78.1M $ | 0.86 % |
| 26 | BioMarin Pharmaceutical Inc | 1,348,623 | 77.2M $ | 0.85 % |
| 27 | Charles River Laboratories International Inc | 337,267 | 76.5M $ | 0.84 % |
| 28 | Arrowhead Pharmaceuticals Inc | 937,699 | 76.4M $ | 0.84 % |
| 29 | Axsome Therapeutics Inc | 305,148 | 74.7M $ | 0.82 % |
| 30 | CYTOKINETICS INC | 844,381 | 71.9M $ | 0.79 % |
| 31 | Krystal Biotech Inc | 182,295 | 67.8M $ | 0.75 % |
| 32 | Halozyme Therapeutics Inc | 831,875 | 65.1M $ | 0.72 % |
| 33 | Praxis Precision Medicines Inc | 185,012 | 61.9M $ | 0.68 % |
| 34 | ABIVAX SA | 458,824 | 61.1M $ | 0.67 % |
| 35 | Alkermes PLC | 1,154,946 | 60.5M $ | 0.67 % |
| 36 | BioNTech SE | 647,133 | 60.2M $ | 0.66 % |
| 37 | VAXCYTE INC | 1,000,469 | 58.2M $ | 0.64 % |
| 38 | KYMERA THERAPEUTICS INC | 504,074 | 57.8M $ | 0.64 % |
| 39 | Apogee Therapeutics Inc | 403,675 | 53.6M $ | 0.59 % |
| 40 | Protagonist Therapeutics Inc | 432,356 | 53M $ | 0.58 % |
| 41 | Rhythm Pharmaceuticals Inc | 470,310 | 52.2M $ | 0.57 % |
| 42 | Repligen Corp | 378,157 | 51.6M $ | 0.57 % |
| 43 | Spyre Therapeutics Inc | 547,684 | 48.6M $ | 0.54 % |
| 44 | Bruker Corp | 787,539 | 47.4M $ | 0.52 % |
| 45 | PTC Therapeutics Inc | 567,871 | 46.3M $ | 0.51 % |
| 46 | Nuvalent Inc | 370,035 | 45.7M $ | 0.50 % |
| 47 | TWIST BIOSCIENCE CORP | 422,334 | 43.4M $ | 0.48 % |
| 48 | Tempus AI Inc | 748,648 | 43.4M $ | 0.48 % |
| 49 | MIRUM PHARMACEUTICALS INC | 351,444 | 41.1M $ | 0.45 % |
| 50 | COGENT BIOSCIENCES INC | 1,042,594 | 40.3M $ | 0.44 % |
| 51 | Xenon Pharmaceuticals Inc | 642,923 | 38.8M $ | 0.43 % |
| 52 | Scholar Rock Holding Corp | 683,504 | 37.6M $ | 0.41 % |
| 53 | TRAVERE THERAPEUTICS INC | 640,421 | 36.4M $ | 0.40 % |
| 54 | Definium Therapeutics Inc | 743,400 | 35M $ | 0.38 % |
| 55 | CRISPR Therapeutics AG | 634,644 | 34.6M $ | 0.38 % |
| 56 | ORUKA THERAPEUTICS INC | 359,218 | 34.2M $ | 0.38 % |
| 57 | Veracyte Inc | 551,371 | 32.4M $ | 0.36 % |
| 58 | 10X Genomics Inc | 799,336 | 30.6M $ | 0.34 % |
| 59 | LEGEND BIOTECH CORP | 1,052,686 | 30.4M $ | 0.33 % |
| 60 | ACADIA Pharmaceuticals Inc | 1,196,003 | 30.3M $ | 0.33 % |
| 61 | CG ONCOLOGY INC | 407,369 | 28.9M $ | 0.32 % |
| 62 | Denali Therapeutics Inc | 1,054,236 | 27.1M $ | 0.30 % |
| 63 | Crinetics Pharmaceuticals Inc | 692,251 | 25.9M $ | 0.29 % |
| 64 | Erasca Inc | 1,325,097 | 24.3M $ | 0.27 % |
| 65 | Tango Therapeutics Inc | 751,469 | 23.5M $ | 0.26 % |
| 66 | Adaptive Biotechnologies Corp | 1,094,715 | 23.5M $ | 0.26 % |
| 67 | IMMUNITYBIO INC | 2,665,564 | 23.3M $ | 0.26 % |
| 68 | Beam Therapeutics Inc | 664,459 | 22.8M $ | 0.25 % |
| 69 | Edgewise Therapeutics Inc | 556,093 | 22.6M $ | 0.25 % |
| 70 | STRUCTURE THERAPEUTICS INC | 414,261 | 22.2M $ | 0.24 % |
| 71 | IMMUNOVANT INC | 573,747 | 22.1M $ | 0.24 % |
| 72 | Ideaya Biosciences Inc | 588,747 | 21.9M $ | 0.24 % |
| 73 | Ultragenyx Pharmaceutical Inc | 635,346 | 21.2M $ | 0.23 % |
| 74 | DYNE THERAPEUTICS INC | 935,489 | 20.8M $ | 0.23 % |
| 75 | Arcutis Biotherapeutics Inc | 782,595 | 20.5M $ | 0.23 % |
| 76 | NEWAMSTERDAM PHARMA COMPANY NV | 566,140 | 19.2M $ | 0.21 % |
| 77 | GRAIL Inc | 280,947 | 19.2M $ | 0.21 % |
| 78 | Relay Therapeutics Inc | 1,015,921 | 19M $ | 0.21 % |
| 79 | uniQure NV | 399,175 | 18.4M $ | 0.20 % |
| 80 | ARCUS BIOSCIENCES INC | 593,218 | 18.3M $ | 0.20 % |
| 81 | TARSUS PHARMACEUTICALS INC | 286,097 | 18M $ | 0.20 % |
| 82 | VERA THERAPEUTICS INC | 414,491 | 17.8M $ | 0.20 % |
| 83 | Enliven Therapeutics Inc | 333,108 | 16.9M $ | 0.19 % |
| 84 | Nurix Therapeutics Inc | 695,275 | 16.9M $ | 0.19 % |
| 85 | ALUMIS INC | 594,125 | 16.7M $ | 0.18 % |
| 86 | Kodiak Sciences Inc | 410,488 | 16M $ | 0.18 % |
| 87 | Vericel Corp | 358,003 | 15.9M $ | 0.18 % |
| 88 | Intellia Therapeutics Inc | 938,715 | 15.9M $ | 0.17 % |
| 89 | CARIS LIFE SCIENCES INC | 869,022 | 15.5M $ | 0.17 % |
| 90 | BioCryst Pharmaceuticals Inc | 1,528,937 | 15.3M $ | 0.17 % |
| 91 | Agios Pharmaceuticals Inc | 395,471 | 14.7M $ | 0.16 % |
| 92 | Disc Medicine Inc | 196,211 | 14.4M $ | 0.16 % |
| 93 | Summit Therapeutics Inc | 955,912 | 13.9M $ | 0.15 % |
| 94 | Aurinia Pharmaceuticals Inc | 800,933 | 13.6M $ | 0.15 % |
| 95 | ADMA Biologics Inc | 1,598,768 | 13.4M $ | 0.15 % |
| 96 | Biohaven Ltd | 890,304 | 13.2M $ | 0.15 % |
| 97 | Zymeworks Inc | 500,560 | 13.1M $ | 0.14 % |
| 98 | AnaptysBio Inc | 193,528 | 13.1M $ | 0.14 % |
| 99 | ABCELLERA BIOLOGICS INC | 1,656,204 | 13M $ | 0.14 % |
| 100 | SAREPTA THERAPEUTICS INC | 718,900 | 12.9M $ | 0.14 % |
Sector breakdown
- Health care 50.3 %
- Unattributed 49.7 %
Titelia assigns each company to a sector, one by one. The unassigned share stays visible, under "Unattributed".
Currency breakdown
- USD 100.0 %
Each line is counted in its quoted currency, as the fund declares it.
Country breakdown
- United States 87.0 %
- Netherlands 4.3 %
- Denmark 2.4 %
- Bermuda 1.4 %
- Ireland 0.8 %
- Canada 0.7 %
- France 0.7 %
- Germany 0.7 %
- Cayman Islands 0.6 %
- Switzerland 0.4 %
- United Kingdom 0.2 %
- British Virgin Islands 0.1 %
- Other countries 0.7 %
Shares are computed on the fund's equities only.
| Rank | Country | Lines | Value | Share |
|---|---|---|---|---|
| 1 | United States | 201 | 7.9B $ | 87.04 % |
| 2 | Netherlands | 4 | 386.3M $ | 4.26 % |
| 3 | Denmark | 2 | 218.5M $ | 2.41 % |
| 4 | Bermuda | 1 | 129.6M $ | 1.43 % |
| 5 | Ireland | 3 | 72.9M $ | 0.80 % |
| 6 | Canada | 3 | 65.4M $ | 0.72 % |
| 7 | France | 2 | 61.8M $ | 0.68 % |
| 8 | Germany | 1 | 60.2M $ | 0.66 % |
| 9 | Cayman Islands | 5 | 50.7M $ | 0.56 % |
| 10 | Switzerland | 3 | 36.4M $ | 0.40 % |
| 11 | United Kingdom | 4 | 16.2M $ | 0.18 % |
| 12 | British Virgin Islands | 1 | 13.2M $ | 0.15 % |
Cite this page
Titelia. "Holdings of iShares Biotechnology ETF". https://titelia.com/en/funds/S000004350