Titelia

Holdings of Select Biotechnology Portfolio

Fidelity Select Portfolios ·161 declared positions · as of Feb 28, 2026

Original filing · Net assets 5.4B $ · Ten largest lines: 55.1 % of the equity sleeve

Sector breakdown

  • Health care 47.5 %
  • Industrials 0.7 %
  • Unattributed 51.7 %

Titelia classification, company by company. The unattributed share stays visible.

Currency breakdown

  • USD 95.9 %
  • EUR 2.4 %
  • CHF 0.9 %
  • DKK 0.8 %
  • SEK 0.1 %

The quoted currency of each line, as declared.

Country breakdown

  • US 87.5 %
  • DK 3.3 %
  • NL 2.8 %
  • BE 2.2 %
  • BM 1.1 %
  • CH 0.9 %
  • FR 0.8 %
  • VG 0.4 %
  • CA 0.3 %
  • IE 0.2 %
  • DE 0.2 %
  • SG 0.1 %
  • Other countries 0.2 %

Shares computed on the equity sleeve.

RankCountryLinesValueShare
1US1354.6B $87.48 %
2DK3173.2M $3.29 %
3NL4148.8M $2.83 %
4BE1116.3M $2.21 %
5BM157.1M $1.09 %
6CH245.9M $0.87 %
7FR244.4M $0.84 %
8VG118.5M $0.35 %
9CA215.2M $0.29 %
10IE311.8M $0.22 %
11DE19.4M $0.18 %
12SG16.8M $0.13 %

Positions

RankCompanySharesValueWeight
1AbbVie Inc 3,049,432707.7M $13.22 %
2Krystal Biotech Inc 1,806,522497.9M $9.30 %
3Gilead Sciences Inc 3,149,952469.2M $8.77 %
4Amgen Inc 1,149,551446.2M $8.34 %
5Alnylam Pharmaceuticals Inc 496,683165.4M $3.09 %
6Praxis Precision Medicines Inc 390,500131.5M $2.46 %
7Ascendis Pharma A/S 558,201130.3M $2.44 %
8Insmed Inc 811,101121.1M $2.26 %
9UCB SA 390,274116.3M $2.17 %
10Argenx SE 149,344114.5M $2.14 %
11Regeneron Pharmaceuticals, Inc. 101,31679.2M $1.48 %
12Moderna Inc 1,432,52976.7M $1.43 %
13Scholar Rock Holding Corp 1,650,44973.1M $1.37 %
14Natera Inc 331,53269M $1.29 %
15Cogent Biosciences Inc 1,691,39465.7M $1.23 %
16CENTESSA PHARMACEUTICALS PLC 2,187,49458.8M $1.10 %
17Biogen Inc 299,43557.4M $1.07 %
18Roivant Sciences Ltd 1,972,71957.1M $1.07 %
19Vertex Pharmaceuticals Inc 112,90056.1M $1.05 %
20Bridgebio Pharma Inc 707,30447M $0.88 %
21Protagonist Therapeutics Inc 506,71346.7M $0.87 %
22Immunome Inc 2,131,66446.6M $0.87 %
23Terns Pharmaceuticals Inc 1,079,18645.5M $0.85 %
24Revolution Medicines Inc 438,77244.8M $0.84 %
25Kymera Therapeutics Inc 462,44142.2M $0.79 %
26Ionis Pharmaceuticals Inc 476,37738.7M $0.72 %
27ArriVent Biopharma Inc 1,680,00338.6M $0.72 %
28Crinetics Pharmaceuticals Inc 926,67138.1M $0.71 %
29Abivax SA 301,60036.6M $0.68 %
30Structure Therapeutics Inc 564,43835.5M $0.66 %
31Disc Medicine Inc 532,17435.5M $0.66 %
32Galderma Group AG 184,66034.8M $0.65 %
33Zealand Pharma A/S 589,13033.9M $0.63 %
34Cytokinetics Inc 503,17531.3M $0.59 %
35Candel Therapeutics Inc 5,911,95131M $0.58 %
36Viridian Therapeutics Inc 1,001,20429.4M $0.55 %
37Vaxcyte Inc 470,45529M $0.54 %
38Stoke Therapeutics Inc 792,59428.9M $0.54 %
39Nuvalent Inc 273,39927.9M $0.52 %
40Apogee Therapeutics Inc 392,75727.5M $0.51 %
41Trevi Therapeutics Inc 2,288,48527.3M $0.51 %
42Annexon Inc 4,733,59626.5M $0.50 %
43Arrowhead Pharmaceuticals Inc 409,37825.9M $0.48 %
44Dianthus Therapeutics Inc 432,21823.9M $0.45 %
45Vor BioPharma Inc 1,536,12523.7M $0.44 %
46Edgewise Therapeutics Inc 776,92523.6M $0.44 %
47United Therapeutics Corp 44,59322.5M $0.42 %
48Intellia Therapeutics Inc 1,607,83322.2M $0.41 %
49Travere Therapeutics Inc 720,34321.5M $0.40 %
50Dyne Therapeutics Inc 1,368,14421.4M $0.40 %
51Corcept Therapeutics Inc 575,64620.6M $0.38 %
52Ideaya Biosciences Inc 637,95720.5M $0.38 %
53Madrigal Pharmaceuticals Inc 47,49520.5M $0.38 %
54Newamsterdam Pharma Co NV 562,50019.9M $0.37 %
55Amylyx Pharmaceuticals Inc 1,219,57518.5M $0.35 %
56Biohaven Ltd 1,603,09618.5M $0.35 %
57Summit Therapeutics Inc 1,089,16918.1M $0.34 %
58Spyre Therapeutics Inc 401,95317.3M $0.32 %
59Arcus Biosciences Inc 831,10016.9M $0.32 %
60Olema Pharmaceuticals Inc 693,10016.8M $0.31 %
61Alumis Inc 561,90016.7M $0.31 %
62Oruka Therapeutics Inc 475,78316.4M $0.31 %
63Bicara Therapeutics Inc 944,90015.9M $0.30 %
64Axsome Therapeutics Inc 92,30315.1M $0.28 %
65Replimune Group Inc 1,864,54514.3M $0.27 %
66Maze Therapeutics Inc 311,88514.2M $0.27 %
67Rapport Therapeutics Inc 471,77313.7M $0.26 %
68Viking Therapeutics Inc 404,25713.7M $0.26 %
69DAMORA THERAPEUTICS INC 454,55913.4M $0.25 %
70BEONE MEDICINES LTD 41,69813.2M $0.25 %
71Xenon Pharmaceuticals Inc 297,36412.9M $0.24 %
72Nuvation Bio Inc 2,164,93312.8M $0.24 %
73Mineralys Therapeutics Inc 421,70012.3M $0.23 %
74Kiniksa Pharmaceuticals International Plc 267,50011.9M $0.22 %
75Solid Biosciences Inc 1,791,16011.1M $0.21 %
76Idorsia Ltd 2,174,28311.1M $0.21 %
77Geron Corp 6,492,51210.9M $0.20 %
78Enliven Therapeutics Inc 363,26710.8M $0.20 %
79Tectonic Therapeutic Inc 442,88910.4M $0.19 %
80Immunocore Holdings PLC 321,50010.4M $0.19 %
81uniQure NV 650,28210.2M $0.19 %
82ZENAS BIOPHARMA INC 380,40010M $0.19 %
83VTV THERAPEUTICS INC 260,3919.9M $0.19 %
84BioNTech SE 85,4009.4M $0.18 %
85Forte Biosciences Inc 310,9659.4M $0.18 %
86Rhythm Pharmaceuticals Inc 99,8039.3M $0.17 %
87PTC Therapeutics Inc 134,5119.2M $0.17 %
88Gubra A/S 145,5549M $0.17 %
89Capricor Therapeutics Inc 314,7008.8M $0.16 %
90Twist Bioscience Corp 170,8258M $0.15 %
91SENSORION SA 18,153,4747.8M $0.15 %
92Aktis Oncology Inc 383,9557.7M $0.14 %
93MannKind Corp 2,185,1017.2M $0.13 %
94Ocular Therapeutix Inc 784,0007M $0.13 %
95Beam Therapeutics Inc 244,9147M $0.13 %
96Immunovant Inc 250,0216.9M $0.13 %
97WaVe Life Sciences Ltd 487,1406.8M $0.13 %
98CytomX Therapeutics Inc 1,222,5406.6M $0.12 %
99Tango Therapeutics Inc 586,0006.5M $0.12 %
100Immuneering Corp 1,290,6986.4M $0.12 %