Titelia

Fund shareholders of Ionis Pharmaceuticals Inc

ISIN US4622221004 · United States · LEI 549300SI4ZGLG0BLUZ92

Fund shareholders
436
Of which ETFs
100 336 other funds
Value held
6.6B $ 346.9M SEK · 4M €
Share of capital
51.7 % of 166.2M shares on Jul 23, 2026

436 funds hold this company. This table lists the 431 that declare it in a regulatory filing. The other 5 publish their holdings in their own reports. They are not in the table.

FundSharesValueWeight in fundShare of capital
Fidelity ZERO Total Market Index Fund Fidelity Concord Street Trust 84,3386.3M $0.02 %0.05 %as of Apr 30, 2026 ↗
Invesco Biotechnology & Genome ETF Invesco Exchange-Traded Fund Trust 82,2406.1M $2.49 %0.05 %as of Apr 30, 2026 ↗
AMG GW&K Small/Mid Cap Core Fund AMG Funds 81,9426.2M $0.86 %0.05 %as of Mar 31, 2026 ↗
iShares U.S. Healthcare ETF iShares Trust 81,2226.1M $0.22 %0.05 %as of Apr 30, 2026 ↗
THE HARTFORD HEALTHCARE FUND HARTFORD MUTUAL FUNDS, INC 78,8935.9M $0.81 %0.05 %as of Apr 30, 2026 ↗
VANGUARD U.S. MOMENTUM FACTOR ETF VANGUARD WELLINGTON FUND 78,5636.4M $0.46 %0.05 %as of Feb 28, 2026 ↗
Invesco Small Cap Growth Portfolio Brighthouse Funds Trust I 76,8545.8M $0.73 %0.05 %as of Mar 31, 2026 ↗
VANGUARD INSTITUTIONAL TOTAL STOCK MARKET INDEX FUND VANGUARD INSTITUTIONAL INDEX FUNDS 75,6795.7M $0.02 %0.05 %as of Mar 31, 2026 ↗
Invesco NASDAQ Next Gen 100 ETF Invesco Exchange-Traded Fund Trust II 72,2075.9M $0.65 %0.04 %as of Feb 28, 2026 ↗
Fidelity Small-Mid Multifactor ETF Fidelity Covington Trust 71,8105.4M $0.23 %0.04 %as of Apr 30, 2026 ↗
RBC Global Opportunities Fund RBC Funds Trust 71,3005.4M $1.25 %0.04 %as of Mar 31, 2026 ↗
Fidelity MSCI Health Care Index ETF FIDELITY COVINGTON TRUST 70,9785.3M $0.19 %0.04 %as of Apr 30, 2026 ↗
HealthInvest Sustainable Healthcare Atle Fund Management AB 69,34949.3M SEK1.55 %0.04 %as of Mar 31, 2026 ↗
Mid Cap Growth Stock Portfolio NORTHWESTERN MUTUAL SERIES FUND INC 68,5285.1M $0.54 %0.04 %as of Mar 31, 2026 ↗
iShares ESG Aware MSCI USA Small-Cap ETF iShares Trust 68,0975.5M $0.24 %0.04 %as of Feb 28, 2026 ↗
Nomura VIP Mid Cap Growth Series Ivy Variable Insurance Portfolios 68,0195.1M $1.51 %0.04 %as of Mar 31, 2026 ↗
Direxion Daily S&P Biotech Bull 3X Shares Direxion Shares ETF Trust 64,9114.9M $0.94 %0.04 %as of Apr 30, 2026 ↗
LVIP T. Rowe Price Structured Mid-Cap Growth Fund LINCOLN VARIABLE INSURANCE PRODUCTS TRUST 63,8624.8M $0.37 %0.04 %as of Mar 31, 2026 ↗
Bridge Builder Tax Managed Small/Mid Cap Fund Bridge Builder Trust 63,2564.7M $0.16 %0.04 %as of Mar 31, 2026 ↗
JNL/Mellon Healthcare Sector Fund JNL Series Trust 63,2254.7M $0.19 %0.04 %as of Mar 31, 2026 ↗
THE HARTFORD SMALL COMPANY FUND HARTFORD MUTUAL FUNDS, INC 62,8034.7M $0.71 %0.04 %as of Apr 30, 2026 ↗
JPMorgan U.S. Momentum Factor ETF J.P. Morgan Exchange-Traded Fund Trust 62,3924.7M $0.21 %0.04 %as of Apr 30, 2026 ↗
Mid Cap Growth Portfolio NEUBERGER BERMAN ADVISERS MANAGEMENT TRUST 61,5724.6M $0.92 %0.04 %as of Mar 31, 2026 ↗
Neuberger Mid Cap Growth Fund NEUBERGER BERMAN EQUITY FUNDS 61,4105M $0.25 %0.04 %as of Feb 28, 2026 ↗
JPMorgan BetaBuilders U.S. Mid Cap Equity ETF J.P. Morgan Exchange-Traded Fund Trust 60,2274.5M $0.22 %0.04 %as of Apr 30, 2026 ↗
Fidelity Momentum Factor ETF Fidelity Covington Trust 60,1694.5M $0.53 %0.04 %as of Apr 30, 2026 ↗
Handelsbanken Global Småbolag Index Criteria Handelsbanken Fonder AB 59,91142.9M SEK0.15 %0.04 %as of Mar 31, 2026 ↗
T. Rowe Price Small-Mid Cap ETF T. Rowe Price Exchange-Traded Funds, Inc. 59,7424.5M $0.29 %0.04 %as of Mar 31, 2026 ↗
iShares Russell 2500 ETF iShares Trust 59,2534.4M $0.17 %0.04 %as of Mar 31, 2026 ↗
FundX Future Fund Opportunities ETF FundX Investment Trust 58,7324.4M $2.24 %0.04 %as of Mar 31, 2026 ↗
Fidelity ZERO Extended Market Index Fund Fidelity Concord Street Trust 57,0044.3M $0.18 %0.03 %as of Apr 30, 2026 ↗
SA JPMorgan Mid-Cap Growth Portfolio SUNAMERICA SERIES TRUST 56,5424.2M $0.64 %0.03 %as of Apr 30, 2026 ↗
American Funds U.S. Small & Mid Cap Equity Fund American Funds U.S. Small & Mid Cap Equity Fund 56,3704.6M $1.18 %0.03 %as of Feb 28, 2026 ↗
STATE STREET SMALL/MID CAP EQUITY INDEX PORTFOLIO STATE STREET INSTITUTIONAL INVESTMENT TRUST 56,3214.2M $0.16 %0.03 %as of Mar 31, 2026 ↗
HealthInvest Small & Mid Cap Healthcare Atle Fund Management AB 55,81839.7M SEK3.98 %0.03 %as of Mar 31, 2026 ↗
T. Rowe Price Health Sciences Portfolio T. ROWE PRICE EQUITY SERIES, INC. 55,3434.2M $0.63 %0.03 %as of Mar 31, 2026 ↗
John Hancock Multifactor Mid Cap ETF John Hancock Exchange-Traded Fund Trust 54,3444.1M $0.08 %0.03 %as of Mar 31, 2026 ↗
T. Rowe Price Integrated U.S. Small-Mid Cap Core Equity Fund T. ROWE PRICE INTEGRATED EQUITY FUNDS, INC. 53,7294M $0.28 %0.03 %as of Mar 31, 2026 ↗
T. Rowe Price Mid-Cap Growth Portfolio T. ROWE PRICE EQUITY SERIES, INC. 53,3794M $0.93 %0.03 %as of Mar 31, 2026 ↗
Mid Cap Growth Trust John Hancock Variable Insurance Trust 53,0204M $0.62 %0.03 %as of Mar 31, 2026 ↗
Small Cap Growth Stock Portfolio NORTHWESTERN MUTUAL SERIES FUND INC 52,8634M $0.54 %0.03 %as of Mar 31, 2026 ↗
Mercer US Small/Mid Cap Equity Fund Mercer Funds 52,5263.9M $0.23 %0.03 %as of Mar 31, 2026 ↗
Schwab 1000 Index Fund SCHWAB INVESTMENTS 51,5513.9M $0.02 %0.03 %as of Apr 30, 2026 ↗
First Trust BuyWrite Income ETF First Trust Exchange-Traded Fund VI 50,8893.8M $0.19 %0.03 %as of Mar 31, 2026 ↗
Tweedy, Browne International Value Fund II - Currency Unhedged Tweedy, Browne Fund Inc. 50,4023.8M $2.41 %0.03 %as of Mar 31, 2026 ↗
iShares Morningstar Small-Cap Growth ETF iShares Trust 46,9013.5M $0.37 %0.03 %as of Apr 30, 2026 ↗
Dimensional U.S. Equity Market ETF Dimensional ETF Trust 46,3913.5M $0.02 %0.03 %as of Apr 30, 2026 ↗
Baron Health Care Fund BARON SELECT FUNDS 45,0003.4M $2.81 %0.03 %as of Mar 31, 2026 ↗
MML Mid Cap Growth Fund MML SERIES INVESTMENT FUND 43,8613.3M $0.94 %0.03 %as of Mar 31, 2026 ↗
VY(R) T. ROWE PRICE DIVERSIFIED MID CAP GROWTH PORTFOLIO Voya Partners Inc 42,5303.2M $0.38 %0.03 %as of Mar 31, 2026 ↗
iShares Russell 3000 ETF iShares Trust 42,3543.2M $0.02 %0.03 %as of Mar 31, 2026 ↗
VictoryShares US Small Mid Cap Value Momentum ETF Victory Portfolios II 41,8053.1M $0.22 %0.03 %as of Mar 31, 2026 ↗
EQ/JPMorgan Value Opportunities Portfolio EQ Advisors Trust 41,2343.1M $0.25 %0.02 %as of Mar 31, 2026 ↗
BlackRock Advantage Small Cap Core Fund BlackRock Funds 41,0613.3M $0.07 %0.02 %as of Feb 27, 2026 ↗
Small-Cap Growth Portfolio PACIFIC SELECT FUND 39,9493M $0.68 %0.02 %as of Mar 31, 2026 ↗
Invesco Dorsey Wright Healthcare Momentum ETF Invesco Exchange-Traded Fund Trust 38,3942.9M $2.37 %0.02 %as of Apr 30, 2026 ↗
HARTFORD SMALL CAP GROWTH HLS FUND HARTFORD SERIES FUND INC 38,0322.9M $0.54 %0.02 %as of Mar 31, 2026 ↗
AMG GW&K Small Cap Growth Fund AMG Funds IV 37,6842.8M $1.35 %0.02 %as of Apr 30, 2026 ↗
Goldman Sachs Small Cap Growth Fund Goldman Sachs Trust 37,1183M $0.71 %0.02 %as of Feb 28, 2026 ↗
Fidelity Nasdaq Composite Index ETF Fidelity Commonwealth Trust 36,6503M $0.03 %0.02 %as of Feb 28, 2026 ↗
First Trust Mid Cap Growth AlphaDEX Fund First Trust Exchange-Traded AlphaDEX Fund 36,5252.7M $0.53 %0.02 %as of Apr 30, 2026 ↗
Blackstone Alternative Multi-Strategy Fund Blackstone Alternative Investment Funds 36,3002.7M $0.08 %0.02 %as of Mar 31, 2026 ↗
First Trust Mid Cap Core AlphaDEX Fund First Trust Exchange-Traded AlphaDEX Fund 36,2632.7M $0.20 %0.02 %as of Apr 30, 2026 ↗
ALGER WEATHERBIE SPECIALIZED GROWTH FUND ALGER FUNDS 35,9382.7M $0.96 %0.02 %as of Apr 30, 2026 ↗
Small Cap Growth Fund VALIC Co I 35,8752.9M $0.54 %0.02 %as of Feb 28, 2026 ↗
VANGUARD ESG U.S. STOCK ETF VANGUARD WORLD FUND 34,9092.8M $0.02 %0.02 %as of Feb 28, 2026 ↗
Tweedy, Browne Insider + Value ETF RBB Fund Trust 33,9412.8M $0.92 %0.02 %as of Feb 28, 2026 ↗
Dimensional U.S. Core Equity 2 ETF Dimensional ETF Trust 32,4292.4M $0.01 %0.02 %as of Apr 30, 2026 ↗
Swedbank Robur Healthcare Swedbank Robur Fonder AB 32,25323.1M SEK0.16 %0.02 %as of Mar 31, 2026 ↗
Fidelity OTC Portfolio Fidelity Securities Fund 31,3622.3M $0.01 %0.02 %as of Apr 30, 2026 ↗
Schwab U.S. Mid-Cap Index Fund SCHWAB CAPITAL TRUST 30,2712.3M $0.09 %0.02 %as of Apr 30, 2026 ↗
T.Rowe Price Small Cap Growth Portfolio Brighthouse Funds Trust II 30,1072.3M $0.21 %0.02 %as of Mar 31, 2026 ↗
State Street(R) SPDR(R) S&P Kensho New Economies Composite ETF SPDR SERIES TRUST 29,9122.2M $0.10 %0.02 %as of Mar 31, 2026 ↗
Buffalo Small Cap Growth Fund Buffalo Funds 29,1052.2M $0.56 %0.02 %as of Mar 31, 2026 ↗
First Trust US Equity Opportunities ETF First Trust Exchange-Traded Fund 28,9052.2M $0.19 %0.02 %as of Mar 31, 2026 ↗
Nationwide Fundamental All Cap Equity Portfolio Nationwide Mutual Funds 28,8232.2M $0.14 %0.02 %as of Apr 30, 2026 ↗
TIFF MULTI-ASSET FUND TIFF Investment Program 28,7242.2M $0.16 %0.02 %as of Mar 31, 2026 ↗
Bridge Builder Large Cap Growth Fund Bridge Builder Trust 28,7052.2M $0.01 %0.02 %as of Mar 31, 2026 ↗
Columbia Variable Portfolio - Acorn Fund COLUMBIA FUNDS VARIABLE SERIES TRUST 28,6572.2M $0.50 %0.02 %as of Mar 31, 2026 ↗
VanEck Morningstar SMID Moat ETF VanEck ETF Trust 28,0582.1M $0.66 %0.02 %as of Mar 31, 2026 ↗
iShares Russell 1000 Value ETF iShares Trust 27,5012.1M $0.00 %0.02 %as of Mar 31, 2026 ↗
iShares Russell Mid-Cap Index Fund BlackRock Funds 27,3692M $0.09 %0.02 %as of Apr 30, 2026 ↗
SA Invesco Growth Opportunities Portfolio SUNAMERICA SERIES TRUST 26,4112M $0.65 %0.02 %as of Apr 30, 2026 ↗
VANGUARD RUSSELL 1000 INDEX FUND VANGUARD SCOTTSDALE FUNDS 26,1802.1M $0.02 %0.02 %as of Feb 28, 2026 ↗
BlackRock Advantage SMID Cap Fund, Inc. BlackRock Advantage SMID Cap Fund, Inc. 25,7221.9M $0.26 %0.02 %as of Mar 31, 2026 ↗
VANGUARD GROWTH AND INCOME FUND VANGUARD QUANTITATIVE FUNDS 25,2001.9M $0.01 %0.02 %as of Mar 31, 2026 ↗
BNY Mellon US Mid Cap Core Equity ETF BNY Mellon ETF Trust 25,1601.9M $0.30 %0.02 %as of Apr 30, 2026 ↗
iShares Russell Small/Mid-Cap Index Fund BlackRock Funds 24,9731.9M $0.15 %0.02 %as of Apr 30, 2026 ↗
Biotechnology Fund Rydex Series Funds 24,8701.9M $1.38 %0.01 %as of Mar 31, 2026 ↗
EQ/Common Stock Index Portfolio EQ Advisors Trust 24,8001.9M $0.03 %0.01 %as of Mar 31, 2026 ↗
SIIT EXTENDED MARKET INDEX FUND SEI INSTITUTIONAL INVESTMENTS TRUST 24,3942M $0.16 %0.01 %as of Feb 28, 2026 ↗
Dimensional US Core Equity Market ETF Dimensional ETF Trust 24,3411.8M $0.02 %0.01 %as of Apr 30, 2026 ↗
Fidelity Flex Mid Cap Index Fund Fidelity Salem Street Trust 23,5051.8M $0.29 %0.01 %as of Apr 30, 2026 ↗
T. Rowe Price Extended Equity Market Index Fund T. ROWE PRICE INDEX TRUST, INC. 22,6441.7M $0.17 %0.01 %as of Mar 31, 2026 ↗
Schwab U.S. Large-Cap Growth Index Fund SCHWAB CAPITAL TRUST 22,3831.7M $0.04 %0.01 %as of Apr 30, 2026 ↗
Penn Series Mid Cap Growth Fund Penn Series Funds Inc 21,5021.6M $1.51 %0.01 %as of Mar 31, 2026 ↗
Nuveen Small/Mid Cap Growth Opportunities Fund Nuveen Investment Funds, Inc. 21,3291.6M $0.94 %0.01 %as of Apr 30, 2026 ↗
HARTFORD SMALL COMPANY HLS FUND HARTFORD SERIES FUND INC 20,2851.5M $0.39 %0.01 %as of Mar 31, 2026 ↗
BIOTECHNOLOGY ULTRASECTOR PROFUND ProFunds 20,0891.5M $0.82 %0.01 %as of Apr 30, 2026 ↗
Victory RS Select Growth Fund Victory Portfolios 20,0701.5M $1.98 %0.01 %as of Mar 31, 2026 ↗

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The funds most exposed to it

The weight is the share of a fund's net assets. The holders table ranks funds by number of shares. This one ranks them by the weight of the company in each fund.

FundWeight in fund
Horizon Kinetics Medical ETF Listed Funds Trust 4.73 %as of Mar 31, 2026 ↗
A&P LIFESCIENCE FUND, FI WELZIA MANAGEMENT, SGIIC, S.A. 4.58 %as of Dec 31, 2025 ↗
HealthInvest Small & Mid Cap Healthcare Atle Fund Management AB 3.98 %as of Mar 31, 2026 ↗
AlphaCentric Life Sciences and Healthcare Fund MUTUAL FUND SERIES TRUST 3.74 %as of Mar 31, 2026 ↗
GESTION BOUTIQUE VI, FI GESTION BOUTIQUE VI / KALDI ANDBANK WEALTH MANAGEMENT, SGIIC, S.A.U. 3.68 %as of Dec 31, 2025 ↗
Tweedy, Browne International Value Fund Tweedy, Browne Fund Inc. 3.17 %as of Mar 31, 2026 ↗
Baron Health Care Fund BARON SELECT FUNDS 2.81 %as of Mar 31, 2026 ↗
Tweedy, Browne Value Fund Tweedy, Browne Fund Inc. 2.79 %as of Mar 31, 2026 ↗
Eventide Healthcare & Life Sciences Fund MUTUAL FUND SERIES TRUST 2.72 %as of Mar 31, 2026 ↗
Invesco Biotechnology & Genome ETF Invesco Exchange-Traded Fund Trust 2.49 %as of Apr 30, 2026 ↗

Quarter after quarter

Each row is one quarter of SEC filings, newest first. The change compares each quarter with the one before.

QuarterShareholdersChangeSharesChange
2026Q2422+2985,444,539+5.7 %
2026Q1393+4580,814,443+5.3 %
2025Q4348+6276,715,982-3.1 %
2025Q3286+1279,201,702-1.0 %
2025Q2274-1279,971,398+0.1 %
2025Q1286-1779,920,146+7.6 %
2024Q4303+474,303,125+10.4 %
2024Q3299-1067,280,894+3.7 %
2024Q2309+1064,888,088+5.0 %
2024Q1299+1561,777,585-4.9 %
2023Q428464,944,400

Institutional managers

483 managers declare this company to the SEC (Form 13F). The table shows the 25 largest.

ManagerSharesValue
FMR LLC24,556,6371.8B $as of Mar 31, 2026
Capital World Investors21,186,3691.6B $as of Mar 31, 2026
BlackRock, Inc.10,442,476784.1M $as of Mar 31, 2026
WELLINGTON MANAGEMENT GROUP LLP6,391,816480M $as of Mar 31, 2026
T. Rowe Price Investment Management, Inc.6,159,027462.5K $as of Mar 31, 2026
TWO SIGMA INVESTMENTS, LP5,857,629439.8M $as of Mar 31, 2026
STATE STREET CORP3,995,564300M $as of Mar 31, 2026
GEODE CAPITAL MANAGEMENT, LLC3,984,332305.2M $as of Mar 31, 2026
ROYAL BANK OF CANADA3,801,815285.5M $as of Mar 31, 2026
PRICE T ROWE ASSOCIATES INC /MD/3,025,251227.2K $as of Mar 31, 2026
JPMORGAN CHASE & CO2,363,567171.4M $as of Mar 31, 2026
Tweedy, Browne Co LLC2,275,625170.9M $as of Mar 31, 2026
Artisan Partners Limited Partnership2,058,308154.6M $as of Mar 31, 2026
BAKER BROS. ADVISORS LP2,047,727153.8M $as of Mar 31, 2026
DEERFIELD MANAGEMENT COMPANY, L.P.1,979,669148.7M $as of Mar 31, 2026
Deep Track Capital, LP1,950,000146.4M $as of Mar 31, 2026
Bellevue Group AG1,818,665136.6M $as of Mar 31, 2026
GOLDMAN SACHS GROUP INC1,699,847127.6M $as of Mar 31, 2026
AMERICAN CENTURY COMPANIES INC1,663,803124.9M $as of Mar 31, 2026
CHARLES SCHWAB INVESTMENT MANAGEMENT INC1,583,266118.9M $as of Mar 31, 2026
FRANKLIN RESOURCES INC1,575,023118.3M $as of Mar 31, 2026
UBS AM, a distinct business unit of UBS ASSET MANAGEMENT AMERICAS LLC1,475,632110.8M $as of Mar 31, 2026
Pictet Asset Management Holding SA1,434,995107.1M $as of Mar 31, 2026
SUMMIT PARTNERS PUBLIC ASSET MANAGEMENT, LLC1,404,033105.4M $as of Mar 31, 2026
Invesco Ltd.1,277,35895.9M $as of Mar 31, 2026

Declared shareholders of Ionis Pharmaceuticals Inc

There are 3 beneficial ownership filings. These stakes do not add up. An asset manager that files includes its own funds, which already appear among the funds on this page.

ShareholderDeclared stakeShares
Capital World Investors 12.80 %21,186,369as of Mar 31, 2026 · SCHEDULE 13G
Vanguard Capital Management 5.05 %8,344,732as of Mar 31, 2026 · SCHEDULE 13G
T. Rowe Price Investment Management, Inc. 3.70 %6,159,027as of Mar 31, 2026 · SCHEDULE 13G

Funds holding the debt of Ionis Pharmaceuticals Inc

55 funds declare 74 bond lines of this company. The table shows the 25 largest holdings. The amount is the one the fund files. It is not a share of the debt, because no regulator publishes the amount outstanding in open access.

FundBond linesValue
Calamos Market Neutral Income Fund236.4M $as of Apr 30, 2026
iShares Convertible Bond ETF228.6M $as of Apr 30, 2026
State Street(R) SPDR(R) Bloomberg Convertible Securities ETF221.8M $as of Mar 31, 2026
Columbia Convertible Securities Fund120.9M $as of Feb 28, 2026
NYLI MacKay Convertible Fund219M $as of Apr 30, 2026
Virtus Income & Growth Fund216.7M $as of Mar 31, 2026
NYLIM VP MacKay Convertible Portfolio216.5M $as of Mar 31, 2026
Virtus Convertible Fund215.3M $as of Mar 31, 2026
Fidelity Convertible Securities Fund313.5M $as of Feb 28, 2026
Calamos Convertible Fund19.6M $as of Apr 30, 2026
Invesco Convertible Securities Fund19.1M $as of Mar 31, 2026
Lord Abbett Convertible Fund18.8M $as of Feb 28, 2026
THE HARTFORD STRATEGIC INCOME FUND27M $as of Apr 30, 2026
Fidelity Strategic Dividend and Income Fund35.9M $as of Feb 28, 2026
WESTWOOD ALTERNATIVE INCOME FUND13M $as of Apr 30, 2026
Putnam Convertible Securities Fund12.8M $as of Apr 30, 2026
Global Opportunities Portfolio12.8M $as of Apr 30, 2026
Voya Global Income & Growth Fund12.3M $as of Feb 28, 2026
American Beacon SSI Alternative Income Fund12.2M $as of Mar 31, 2026
Calamos Global Opportunities Fund11.7M $as of Apr 30, 2026
THE HARTFORD BALANCED INCOME FUND11.7M $as of Apr 30, 2026
Calamos Global Convertible Fund11.7M $as of Apr 30, 2026
Hartford Strategic Income ETF21.5M $as of Apr 30, 2026
Calvert Bond Fund11.4M $as of Mar 31, 2026
High Yield Bond Fund11.3M $as of Feb 28, 2026
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Titelia. "Fund shareholders of Ionis Pharmaceuticals Inc". https://titelia.com/en/stocks/ionis-pharmaceuticals-inc-US4622221004