Funds holding Ionis Pharmaceuticals Inc
431 funds declare a position · 100 ETFs and 331 other funds · 6.6B $· 346.9M SEK· 4M € · US4622221004
Each line carries its report date.
| Rank | Fund | Shares | Value | Weight | |
|---|---|---|---|---|---|
| 201 | Timothy Plan Aggressive Growth Fund TIMOTHY PLAN | 19,945 | 1.5M $ | 1.28 % | as of Mar 31, 2026 · Original filing |
| 202 | VANGUARD TAX-MANAGED BALANCED FUND VANGUARD TAX-MANAGED FUNDS | 19,888 | 1.5M $ | 0.01 % | as of Mar 31, 2026 · Original filing |
| 203 | U.S. Sustainability Core 1 Portfolio DFA INVESTMENT DIMENSIONS GROUP INC | 19,821 | 1.5M $ | 0.02 % | as of Apr 30, 2026 · Original filing |
| 204 | AST Large-Cap Value Portfolio Advanced Series Trust | 19,724 | 1.5M $ | 0.04 % | as of Mar 31, 2026 · Original filing |
| 205 | AlphaCentric Life Sciences and Healthcare Fund MUTUAL FUND SERIES TRUST | 19,587 | 1.5M $ | 3.74 % | as of Mar 31, 2026 · Original filing |
| 206 | The Hartford Small Cap Growth Fund HARTFORD MUTUAL FUNDS II, INC | 19,349 | 1.4M $ | 0.47 % | as of Apr 30, 2026 · Original filing |
| 207 | Health Sciences Trust John Hancock Variable Insurance Trust | 19,249 | 1.4M $ | 0.64 % | as of Mar 31, 2026 · Original filing |
| 208 | Calamos Growth Fund CALAMOS INVESTMENT TRUST/IL | 19,141 | 1.4M $ | 0.08 % | as of Apr 30, 2026 · Original filing |
| 209 | Calvert U.S. Large Cap Core Responsible Index Fund Calvert Responsible Index Series, Inc. | 19,122 | 1.4M $ | 0.03 % | as of Mar 31, 2026 · Original filing |
| 210 | Victory Extended Market Index Fund Victory Portfolios III | 18,519 | 1.4M $ | 0.18 % | as of Apr 30, 2026 · Original filing |
| 211 | Neuberger Core Equity ETF Neuberger Berman ETF Trust | 17,781 | 1.4M $ | 0.16 % | as of Feb 28, 2026 · Original filing |
| 212 | iShares Russell Mid-Cap Value ETF iShares Trust | 17,745 | 1.3M $ | 0.01 % | as of Mar 31, 2026 · Original filing |
| 213 | Invesco Dorsey Wright SmallCap Momentum ETF Invesco Exchange-Traded Fund Trust II | 17,502 | 1.4M $ | 0.37 % | as of Feb 28, 2026 · Original filing |
| 214 | iShares MSCI USA Small-Cap Min Vol Factor ETF iShares Trust | 17,241 | 1.3M $ | 0.45 % | as of Apr 30, 2026 · Original filing |
| 215 | VANGUARD MARKET NEUTRAL FUND VANGUARD MONTGOMERY FUNDS | 17,120 | 1.3M $ | 0.30 % | as of Mar 31, 2026 · Original filing |
| 216 | Transamerica T. Rowe Price Small Cap VP TRANSAMERICA SERIES TRUST | 17,108 | 1.3M $ | 0.20 % | as of Mar 31, 2026 · Original filing |
| 217 | Fidelity Fundamental Large Cap Growth ETF Fidelity Covington Trust | 16,403 | 1.2M $ | 0.21 % | as of Apr 30, 2026 · Original filing |
| 218 | MFS Blended Research Small Cap Equity Fund MFS SERIES TRUST X | 16,161 | 1.3M $ | 0.41 % | as of Feb 28, 2026 · Original filing |
| 219 | First Trust Nasdaq BuyWrite Income ETF First Trust Exchange-Traded Fund VI | 16,085 | 1.2M $ | 0.16 % | as of Mar 31, 2026 · Original filing |
| 220 | Franklin Small-Mid Cap Growth VIP Fund Franklin Templeton Variable Insurance Products Trust | 16,040 | 1.2M $ | 0.32 % | as of Mar 31, 2026 · Original filing |
| 221 | LVIP Blended Mid Cap Managed Volatility Fund LINCOLN VARIABLE INSURANCE PRODUCTS TRUST | 16,005 | 1.2M $ | 0.18 % | as of Mar 31, 2026 · Original filing |
| 222 | T. Rowe Price Total Equity Market Index Fund T. ROWE PRICE INDEX TRUST, INC. | 15,856 | 1.2M $ | 0.04 % | as of Mar 31, 2026 · Original filing |
| 223 | Calvert U.S. Large Cap Value Responsible Index Fund Calvert Responsible Index Series, Inc. | 15,236 | 1.1M $ | 0.06 % | as of Mar 31, 2026 · Original filing |
| 224 | U.S. Small and Mid Cap Equity Fund AMERICAN FUNDS INSURANCE SERIES | 15,007 | 1.1M $ | 1.16 % | as of Mar 31, 2026 · Original filing |
| 225 | Variable Portfolio - Partners Small Cap Growth Fund Columbia Funds Variable Series Trust II | 14,504 | 1.1M $ | 0.33 % | as of Mar 31, 2026 · Original filing |
| 226 | T. Rowe Price Small-Cap Stock Fund, Inc. T. ROWE PRICE SMALL-CAP STOCK FUND, INC. | 14,454 | 1.1M $ | 0.01 % | as of Mar 31, 2026 · Original filing |
| 227 | Goldman Sachs Large Cap Equity Fund Goldman Sachs Trust | 14,011 | 1.1M $ | 0.08 % | as of Feb 28, 2026 · Original filing |
| 228 | Invesco V.I. Health Care Fund AIM Variable Insurance Funds (Invesco Variable Insurance Funds) | 13,962 | 1M $ | 0.71 % | as of Mar 31, 2026 · Original filing |
| 229 | EQ/T.Rowe Price Health Sciences Portfolio EQ Advisors Trust | 13,552 | 1M $ | 0.64 % | as of Mar 31, 2026 · Original filing |
| 230 | Invesco V.I. Main Street Mid Cap Fund AIM Variable Insurance Funds (Invesco Variable Insurance Funds) | 13,157 | 988K $ | 0.66 % | as of Mar 31, 2026 · Original filing |
| 231 | T. Rowe Price Mid-Cap Index Fund T. ROWE PRICE INDEX TRUST, INC. | 13,141 | 986.8K $ | 0.26 % | as of Mar 31, 2026 · Original filing |
| 232 | EQ/Large Cap Growth Index Portfolio EQ Advisors Trust | 13,135 | 986.3K $ | 0.04 % | as of Mar 31, 2026 · Original filing |
| 233 | Columbia Research Enhanced Core ETF Columbia ETF Trust I | 13,092 | 978.8K $ | 0.02 % | as of Apr 30, 2026 · Original filing |
| 234 | Small Cap Stock Trust John Hancock Variable Insurance Trust | 13,037 | 978.9K $ | 0.40 % | as of Mar 31, 2026 · Original filing |
| 235 | VANGUARD RUSSELL 3000 INDEX FUND VANGUARD SCOTTSDALE FUNDS | 12,835 | 1M $ | 0.02 % | as of Feb 28, 2026 · Original filing |
| 236 | Venerable Mid Cap Index Fund Venerable Variable Insurance Trust | 12,651 | 950K $ | 0.09 % | as of Mar 31, 2026 · Original filing |
| 237 | AQR Large Cap Momentum Style Fund AQR Funds | 12,611 | 947K $ | 0.17 % | as of Mar 31, 2026 · Original filing |
| 238 | DWS Small Mid Cap Value VIP DEUTSCHE DWS VARIABLE SERIES II | 12,600 | 946.1K $ | 1.14 % | as of Mar 31, 2026 · Original filing |
| 239 | Schwab 1000 Index ETF SCHWAB STRATEGIC TRUST | 12,460 | 1M $ | 0.02 % | as of Feb 28, 2026 · Original filing |
| 240 | SIIT U.S. Equity Factor Allocation Fund SEI INSTITUTIONAL INVESTMENTS TRUST | 12,264 | 995.2K $ | 0.03 % | as of Feb 28, 2026 · Original filing |
| 241 | Fidelity Series Large Cap Growth Index Fund Fidelity Salem Street Trust | 12,250 | 915.8K $ | 0.04 % | as of Apr 30, 2026 · Original filing |
| 242 | iShares MSCI World Small-Cap ETF iShares Trust | 12,177 | 988.2K $ | 0.12 % | as of Feb 28, 2026 · Original filing |
| 243 | Virtus Biotech Etf ETFis Series Trust I | 11,708 | 875.3K $ | 1.48 % | as of Apr 30, 2026 · Original filing |
| 244 | Horizon Kinetics Medical ETF Listed Funds Trust | 11,428 | 858.1K $ | 4.73 % | as of Mar 31, 2026 · Original filing |
| 245 | Global Atlantic BlackRock Disciplined Mid Cap Growth Portfolio Forethought Variable Insurance Trust | 11,382 | 854.7K $ | 0.36 % | as of Mar 31, 2026 · Original filing |
| 246 | JNL/Mellon U.S. Stock Market Index Fund JNL Series Trust | 11,368 | 853.6K $ | 0.02 % | as of Mar 31, 2026 · Original filing |
| 247 | BlackRock Global Allocation Fund, Inc. BlackRock Global Allocation Fund, Inc. | 11,313 | 845.8K $ | 0.00 % | as of Apr 30, 2026 · Original filing |
| 248 | MOA MID CAP VALUE FUND MoA Funds Corp | 11,310 | 849.3K $ | 0.46 % | as of Mar 31, 2026 · Original filing |
| 249 | HARTFORD HEALTHCARE HLS FUND HARTFORD SERIES FUND INC | 11,237 | 843.8K $ | 0.81 % | as of Mar 31, 2026 · Original filing |
| 250 | JNL/RAFI Multi-Factor U.S. Equity Fund JNL Series Trust | 11,141 | 836.6K $ | 0.04 % | as of Mar 31, 2026 · Original filing |
| 251 | VIP Extended Market Index Portfolio Variable Insurance Products Fund II | 10,806 | 811.4K $ | 0.18 % | as of Mar 31, 2026 · Original filing |
| 252 | Penn Series SMID Cap Growth Fund Penn Series Funds Inc | 10,691 | 802.8K $ | 1.25 % | as of Mar 31, 2026 · Original filing |
| 253 | Brighthouse/Wellington Large Cap Research Portfolio Brighthouse Funds Trust I | 10,622 | 797.6K $ | 0.03 % | as of Mar 31, 2026 · Original filing |
| 254 | EQ/Large Cap Growth Managed Volatility Portfolio EQ Advisors Trust | 10,470 | 786.2K $ | 0.02 % | as of Mar 31, 2026 · Original filing |
| 255 | MoA Mid Cap Growth Fund MoA Funds Corp | 10,406 | 781.4K $ | 0.76 % | as of Mar 31, 2026 · Original filing |
| 256 | Health Sciences Portfolio PACIFIC SELECT FUND | 10,319 | 774.9K $ | 0.22 % | as of Mar 31, 2026 · Original filing |
| 257 | iShares Total U.S. Stock Market Index Fund BlackRock Funds | 10,046 | 751K $ | 0.02 % | as of Apr 30, 2026 · Original filing |
| 258 | First Trust Multi Cap Growth AlphaDEX Fund First Trust Exchange-Traded AlphaDEX Fund | 10,044 | 750.9K $ | 0.16 % | as of Apr 30, 2026 · Original filing |
| 259 | Growth Equity Index Fund GuideStone Funds | 9,623 | 722.6K $ | 0.11 % | as of Mar 31, 2026 · Original filing |
| 260 | Invesco Nasdaq Biotechnology ETF Invesco Exchange-Traded Fund Trust II | 9,163 | 743.6K $ | 0.98 % | as of Feb 28, 2026 · Original filing |
| 261 | SA Multi-Managed Mid Cap Growth Portfolio SEASONS SERIES TRUST | 8,900 | 668.3K $ | 0.46 % | as of Mar 31, 2026 · Original filing |
| 262 | MassMutual Small Cap Growth Equity Fund MASSMUTUAL SELECT FUNDS | 8,419 | 632.2K $ | 0.11 % | as of Mar 31, 2026 · Original filing |
| 263 | Invesco Russell 1000 Equal Weight ETF Invesco Exchange-Traded Fund Trust II | 8,238 | 668.5K $ | 0.08 % | as of Feb 28, 2026 · Original filing |
| 264 | T. Rowe Price Institutional Small-Cap Stock Fund T. Rowe Price Equity Funds, Inc. | 7,921 | 594.8K $ | 0.01 % | as of Mar 31, 2026 · Original filing |
| 265 | Voya RussellTM Mid Cap Index Portfolio Voya VARIABLE PORTFOLIOS INC | 7,896 | 592.9K $ | 0.09 % | as of Mar 31, 2026 · Original filing |
| 266 | AMG GW&K Small/Mid Cap Growth Fund AMG Funds IV | 7,702 | 575.8K $ | 1.38 % | as of Apr 30, 2026 · Original filing |
| 267 | Goldman Sachs Variable Insurance Trust Mid Cap Growth Fund Goldman Sachs Variable Insurance Trust | 7,572 | 568.6K $ | 0.97 % | as of Mar 31, 2026 · Original filing |
| 268 | iShares Disciplined Volatility Equity Active ETF BlackRock ETF Trust | 7,551 | 564.5K $ | 0.03 % | as of Apr 30, 2026 · Original filing |
| 269 | Victory RS Mid Cap Growth Fund Victory Portfolios | 7,520 | 564.7K $ | 0.91 % | as of Mar 31, 2026 · Original filing |
| 270 | ProShares Ultra Nasdaq Biotechnology ProShares Trust | 7,479 | 606.9K $ | 0.66 % | as of Feb 28, 2026 · Original filing |
| 271 | Inspire 500 ETF Northern Lights Fund Trust IV | 6,957 | 564.6K $ | 0.08 % | as of Feb 28, 2026 · Original filing |
| 272 | iShares Dow Jones U.S. ETF iShares Trust | 6,947 | 519.4K $ | 0.02 % | as of Apr 30, 2026 · Original filing |
| 273 | JNL/RAFI Fundamental U.S. Small Cap Fund JNL Series Trust | 6,876 | 516.3K $ | 0.14 % | as of Mar 31, 2026 · Original filing |
| 274 | Calvert U.S. Mid Cap Core Responsible Index Fund Calvert Responsible Index Series, Inc. | 6,669 | 500.8K $ | 0.12 % | as of Mar 31, 2026 · Original filing |
| 275 | Morgan Stanley Pathway Small-Mid Cap Equity ETF MORGAN STANLEY PATHWAY FUNDS | 6,605 | 536K $ | 0.07 % | as of Feb 28, 2026 · Original filing |
| 276 | Multi-Manager Directional Alternative Strategies Fund COLUMBIA FUNDS SERIES TRUST I | 6,587 | 492.4K $ | 0.16 % | as of Apr 30, 2026 · Original filing |
| 277 | iShares Morningstar Small-Cap ETF iShares Trust | 6,539 | 488.9K $ | 0.18 % | as of Apr 30, 2026 · Original filing |
| 278 | VANGUARD RUSSELL 1000 VALUE INDEX FUND VANGUARD SCOTTSDALE FUNDS | 6,538 | 530.6K $ | 0.00 % | as of Feb 28, 2026 · Original filing |
| 279 | T. Rowe Price Tax-Efficient Equity Fund T. ROWE PRICE TAX-EFFICIENT FUNDS, INC. | 6,500 | 527.5K $ | 0.04 % | as of Feb 28, 2026 · Original filing |
| 280 | Dimensional US Core Equity 1 ETF Dimensional ETF Trust | 6,267 | 468.5K $ | 0.02 % | as of Apr 30, 2026 · Original filing |
| 281 | JNL/Morningstar SMID Moat Focus Index Fund JNL Series Trust | 6,249 | 469.2K $ | 0.65 % | as of Mar 31, 2026 · Original filing |
| 282 | PRAXIS SMALL CAP INDEX FUND Praxis Mutual Funds | 6,232 | 468K $ | 0.23 % | as of Mar 31, 2026 · Original filing |
| 283 | PROFUND VP BIOTECHNOLOGY ProFunds | 6,198 | 465.4K $ | 1.12 % | as of Mar 31, 2026 · Original filing |
| 284 | Morgan Stanley Pathway Large Cap Equity ETF MORGAN STANLEY PATHWAY FUNDS | 5,998 | 486.7K $ | 0.01 % | as of Feb 28, 2026 · Original filing |
| 285 | Franklin Genomic Advancements ETF Franklin Templeton ETF Trust | 5,957 | 447.3K $ | 2.09 % | as of Mar 31, 2026 · Original filing |
| 286 | FlexShares Morningstar US Market Factor Tilt Index Fund FlexShares Trust | 5,816 | 434.8K $ | 0.02 % | as of Apr 30, 2026 · Original filing |
| 287 | Tema Heart & Health ETF Tema ETF Trust | 5,673 | 460.4K $ | 0.83 % | as of Feb 28, 2026 · Original filing |
| 288 | BlackRock Advantage SMID Cap V.I. Fund BlackRock Variable Series Funds, Inc. | 5,484 | 411.8K $ | 0.27 % | as of Mar 31, 2026 · Original filing |
| 289 | Goldman Sachs MarketBeta U.S. 1000 Equity ETF Goldman Sachs ETF Trust II | 5,386 | 437.1K $ | 0.02 % | as of Feb 28, 2026 · Original filing |
| 290 | Franklin DynaTech VIP Fund Franklin Templeton Variable Insurance Products Trust | 5,309 | 398.7K $ | 0.25 % | as of Mar 31, 2026 · Original filing |
| 291 | NYLIM VP Wellington Small Cap Portfolio NEW YORK LIFE INVESTMENTS VP FUNDS TRUST | 5,299 | 397.9K $ | 0.11 % | as of Mar 31, 2026 · Original filing |
| 292 | JPMorgan Global Allocation Fund JPMorgan Trust I | 5,131 | 383.6K $ | 0.01 % | as of Apr 30, 2026 · Original filing |
| 293 | PD Large-Cap Growth Index Portfolio PACIFIC SELECT FUND | 5,103 | 383.2K $ | 0.04 % | as of Mar 31, 2026 · Original filing |
| 294 | Column Small Cap Fund Trust for Professional Managers | 4,974 | 403.6K $ | 0.08 % | as of Feb 28, 2026 · Original filing |
| 295 | OneAscent Enhanced Small and Mid Cap ETF Unified Series Trust | 4,974 | 403.6K $ | 0.55 % | as of Feb 28, 2026 · Original filing |
| 296 | Diversified Equity Master Portfolio Master Investment Portfolio | 4,942 | 371.1K $ | 0.01 % | as of Mar 31, 2026 · Original filing |
| 297 | Value Equity Index Fund GuideStone Funds | 4,915 | 369.1K $ | 0.07 % | as of Mar 31, 2026 · Original filing |
| 298 | Goldman Sachs Absolute Return Tracker Fund GOLDMAN SACHS TRUST | 4,900 | 367.9K $ | 0.01 % | as of Mar 31, 2026 · Original filing |
| 299 | DANA EPIPHANY SMALL CAP EQUITY FUND Valued Advisers Trust | 4,839 | 361.8K $ | 1.06 % | as of Apr 30, 2026 · Original filing |
| 300 | LargeCap Growth Fund I Principal Funds, Inc | 4,623 | 345.6K $ | 0.01 % | as of Apr 30, 2026 · Original filing |
Institutional managers
483 managers declare this company to the SEC (Form 13F). These positions are not counted in the totals above: a manager and its own funds file separately.
| Manager | Shares | Value | |
|---|---|---|---|
| FMR LLC | 24,556,637 | 1.8B $ | as of Mar 31, 2026 |
| Capital World Investors | 21,186,369 | 1.6B $ | as of Mar 31, 2026 |
| BlackRock, Inc. | 10,442,476 | 784.1M $ | as of Mar 31, 2026 |
| WELLINGTON MANAGEMENT GROUP LLP | 6,391,816 | 480M $ | as of Mar 31, 2026 |
| TWO SIGMA INVESTMENTS, LP | 5,857,629 | 439.8M $ | as of Mar 31, 2026 |
| GEODE CAPITAL MANAGEMENT, LLC | 3,984,332 | 305.2M $ | as of Mar 31, 2026 |
| STATE STREET CORP | 3,995,564 | 300M $ | as of Mar 31, 2026 |
| ROYAL BANK OF CANADA | 3,801,815 | 285.5M $ | as of Mar 31, 2026 |
| JPMORGAN CHASE & CO | 2,363,567 | 171.4M $ | as of Mar 31, 2026 |
| Tweedy, Browne Co LLC | 2,275,625 | 170.9M $ | as of Mar 31, 2026 |
| Artisan Partners Limited Partnership | 2,058,308 | 154.6M $ | as of Mar 31, 2026 |
| BAKER BROS. ADVISORS LP | 2,047,727 | 153.8M $ | as of Mar 31, 2026 |
| DEERFIELD MANAGEMENT COMPANY, L.P. | 1,979,669 | 148.7M $ | as of Mar 31, 2026 |
| Deep Track Capital, LP | 1,950,000 | 146.4M $ | as of Mar 31, 2026 |
| Bellevue Group AG | 1,818,665 | 136.6M $ | as of Mar 31, 2026 |
| GOLDMAN SACHS GROUP INC | 1,699,847 | 127.6M $ | as of Mar 31, 2026 |
| AMERICAN CENTURY COMPANIES INC | 1,663,803 | 124.9M $ | as of Mar 31, 2026 |
| CHARLES SCHWAB INVESTMENT MANAGEMENT INC | 1,583,266 | 118.9M $ | as of Mar 31, 2026 |
| FRANKLIN RESOURCES INC | 1,575,023 | 118.3M $ | as of Mar 31, 2026 |
| UBS AM, a distinct business unit of UBS ASSET MANAGEMENT AMERICAS LLC | 1,475,632 | 110.8M $ | as of Mar 31, 2026 |
| Pictet Asset Management Holding SA | 1,434,995 | 107.1M $ | as of Mar 31, 2026 |
| SUMMIT PARTNERS PUBLIC ASSET MANAGEMENT, LLC | 1,404,033 | 105.4M $ | as of Mar 31, 2026 |
| Invesco Ltd. | 1,277,358 | 95.9M $ | as of Mar 31, 2026 |
| MILLENNIUM MANAGEMENT LLC | 1,051,506 | 79M $ | as of Mar 31, 2026 |
| MORGAN STANLEY | 1,026,509 | 77.1M $ | as of Mar 31, 2026 |