Titelia

Holdings of Health Sciences Trust

John Hancock Variable Insurance Trust · Original filing · Compare with another fund · Report an error

Net assets
227.2M $ including 225M $ in equities, 99.0 %
Positions
170 in 13 countries
Top ten
40.0 % of net assets
Filed on
Mar 31, 2026
Portfolio shape

Positions

RankCompanySharesValueWeight
1Eli Lilly & Co 25,20823.2M $10.20 %
2Thermo Fisher Scientific Inc 19,0529.4M $4.12 %
3Intuitive Surgical Inc 18,2758.4M $3.71 %
4Stryker Corp 24,3458M $3.52 %
5Merck & Co Inc 65,6887.9M $3.48 %
6AstraZeneca PLC 37,1297.3M $3.22 %
7UnitedHealth Group Inc 26,3097.1M $3.13 %
8Argenx SE 9,3146.8M $2.99 %
9AbbVie Inc 30,1256.6M $2.88 %
10Regeneron Pharmaceuticals, Inc. 7,9056.1M $2.69 %
11Gilead Sciences Inc 43,1006M $2.64 %
12Johnson & Johnson 22,9725.6M $2.47 %
13Vertex Pharmaceuticals Inc 12,5285.6M $2.46 %
14Danaher Corp 24,9644.7M $2.08 %
15Alnylam Pharmaceuticals Inc 11,5413.8M $1.68 %
16Ascendis Pharma A/S 14,4303.3M $1.45 %
17United Therapeutics Corp 5,4913.3M $1.43 %
18Revolution Medicines Inc 32,4743.2M $1.39 %
19BeOne Medicines Ltd 124,5982.8M $1.23 %
20Protagonist Therapeutics Inc 25,1652.7M $1.17 %
21Roivant Sciences Ltd 95,2842.6M $1.16 %
22Insmed Inc 15,3822.5M $1.11 %
23Summit Therapeutics Inc 131,1772.5M $1.09 %
24Natera Inc 12,0572.4M $1.06 %
25Tenet Healthcare Corp 12,4422.3M $1.03 %
26Amgen Inc 6,6372.3M $1.03 %
27BrightSpring Health Services Inc 54,0002.3M $1.01 %
28Boston Scientific Corp 34,2932.2M $0.95 %
29HCA Healthcare Inc 4,4362.1M $0.92 %
30Guardant Health Inc 22,7132.1M $0.92 %
31CVS Health Corp 28,4102M $0.90 %
32Kymera Therapeutics Inc 22,0891.8M $0.81 %
33Cigna Group/The 6,6701.8M $0.78 %
34CG oncology Inc 24,0561.6M $0.72 %
35Cardinal Health, Inc. 7,6521.6M $0.71 %
36Elevance Health Inc 5,2921.5M $0.68 %
37Krystal Biotech Inc 5,9441.5M $0.68 %
38Scholar Rock Holding Corp 29,9021.5M $0.65 %
39Bridgebio Pharma Inc 19,5311.5M $0.64 %
40Ionis Pharmaceuticals Inc 19,2491.4M $0.64 %
41Chugai Pharmaceutical Co Ltd 25,0001.4M $0.61 %
42Praxis Precision Medicines Inc 4,2711.4M $0.61 %
43Structure Therapeutics Inc 28,2411.4M $0.60 %
44Celcuity Inc 11,8191.3M $0.59 %
45Royalty Pharma PLC 27,6591.3M $0.58 %
46CENTESSA PHARMACEUTICALS PLC 31,4571.2M $0.55 %
47Cencora Inc 3,9351.2M $0.54 %
48Vera Therapeutics Inc 27,3781.1M $0.48 %
49Nuvalent Inc 10,2081M $0.46 %
50Apogee Therapeutics Inc 12,3071M $0.46 %
51Edwards Lifesciences Corp 12,7851M $0.45 %
52Incyte Corp 10,7341M $0.44 %
53Abivax SA 9,0161M $0.44 %
54Spyre Therapeutics Inc 19,484982.8K $0.43 %
55Cytokinetics Inc 14,740971.5K $0.43 %
56Dianthus Therapeutics Inc 11,216941.2K $0.41 %
57Crinetics Pharmaceuticals Inc 25,378921.7K $0.41 %
58Madrigal Pharmaceuticals Inc 1,671874.7K $0.39 %
59Immunome Inc 39,589865.8K $0.38 %
60IQVIA Holdings Inc 4,791817.1K $0.36 %
61Kodiak Sciences Inc 21,314812.5K $0.36 %
62Belite Bio Inc 4,800765.3K $0.34 %
63Monte Rosa Therapeutics Inc 45,126742.3K $0.33 %
64Terns Pharmaceuticals Inc 13,841729.7K $0.32 %
65Mirum Pharmaceuticals Inc 7,430686.4K $0.30 %
66Axsome Therapeutics Inc 3,961669.5K $0.29 %
67Moderna Inc 12,539637K $0.28 %
68Alignment Healthcare Inc 34,394606K $0.27 %
69Beam Therapeutics Inc 25,010596K $0.26 %
70Alumis Inc 26,808590.6K $0.26 %
71IDEXX Laboratories Inc 1,028577.6K $0.25 %
72Revvity Inc 6,470566.8K $0.25 %
73Sionna Therapeutics Inc 14,085564.7K $0.25 %
74Sonova Holding AG 2,403547.9K $0.24 %
75MBX Biosciences Inc 17,761530.2K $0.23 %
76West Pharmaceutical Services Inc 2,100526.3K $0.23 %
77McKesson Corp 608526.1K $0.23 %
78ORIC Pharmaceuticals Inc 41,012519.6K $0.23 %
79Rhythm Pharmaceuticals Inc 5,825506.6K $0.22 %
80Immunocore Holdings PLC 16,454496.1K $0.22 %
81Rapport Therapeutics Inc 15,736492.4K $0.22 %
82Arrowhead Pharmaceuticals Inc 7,841491.6K $0.22 %
83Nurix Therapeutics Inc 31,364486.1K $0.21 %
84Caris Life Sciences Inc 26,832479.8K $0.21 %
85Erasca Inc 28,600462.7K $0.20 %
86Oruka Therapeutics Inc 9,120447.3K $0.20 %
87Billiontoone Inc 5,603442.3K $0.19 %
88Centene Corp 13,351437.1K $0.19 %
89Vaxcyte Inc 7,498435.7K $0.19 %
90Bio-Rad Laboratories Inc 1,537428.4K $0.19 %
91Palvella Therapeutics Inc 3,373420.4K $0.19 %
92MoonLake Immunotherapeutics 21,385398.6K $0.18 %
93Encompass Health Corp 3,941381.2K $0.17 %
94Relay Therapeutics Inc 36,491363.1K $0.16 %
95BEONE MEDICINES LTD 1,214360.5K $0.16 %
96Kestra Medical Technologies Ltd 17,599350.7K $0.15 %
97WaVe Life Sciences Ltd 47,883347.2K $0.15 %
98Charles River Laboratories International Inc 2,002345.3K $0.15 %
99Repligen Corp 2,923344.4K $0.15 %
100Bicara Therapeutics Inc 17,135340.8K $0.15 %

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Sector breakdown

  • Health care 66.3 %
  • Unattributed 33.7 %

Titelia classification, company by company. The unattributed share stays visible.

Currency breakdown

  • USD 97.8 %
  • HKD 1.2 %
  • JPY 0.6 %
  • CHF 0.2 %
  • EUR 0.1 %

The quoted currency of each line, as declared.

Country breakdown

  • United States 87.0 %
  • United Kingdom 3.3 %
  • Netherlands 3.2 %
  • Denmark 1.6 %
  • Bermuda 1.3 %
  • Hong Kong SAR China 1.2 %
  • Japan 0.6 %
  • Cayman Islands 0.6 %
  • France 0.5 %
  • Switzerland 0.2 %
  • Singapore 0.2 %
  • British Virgin Islands 0.1 %

Shares computed on the equity sleeve.

RankCountryLinesValueShare
1United States149195.8M $87.04 %
2United Kingdom27.4M $3.31 %
3Netherlands37.2M $3.20 %
4Denmark23.6M $1.62 %
5Bermuda23M $1.33 %
6Hong Kong SAR China12.8M $1.24 %
7Japan11.4M $0.61 %
8Cayman Islands41.4M $0.60 %
9France21.2M $0.52 %
10Switzerland1547.9K $0.24 %
11Singapore1347.2K $0.15 %
12British Virgin Islands1266.6K $0.12 %
Cite this page

Titelia. "Holdings of Health Sciences Trust". https://titelia.com/en/funds/S000008239