Holdings of State Street(R) SPDR(R) S&P(R) Biotech ETF
SPDR SERIES TRUST · Original filing · Compare with another fund · Report an error
- Net assets
- 7.4B $ including 7.4B $ in equities, 99.8 %
- Positions
- 147 in 6 countries
- Top ten
- 13.7 % of net assets
- Filed on
- Mar 31, 2026
Portfolio shape
Positions
| Rank | Company | Shares | Value | Weight |
|---|---|---|---|---|
| 1 | Apellis Pharmaceuticals Inc | 3,390,454 | 136.4M $ | 1.83 % |
| 2 | Alkermes PLC | 3,050,830 | 107.9M $ | 1.45 % |
| 3 | Madrigal Pharmaceuticals Inc | 196,408 | 102.8M $ | 1.38 % |
| 4 | TG Therapeutics Inc | 3,020,301 | 100.3M $ | 1.35 % |
| 5 | Insmed Inc | 607,845 | 99.4M $ | 1.34 % |
| 6 | Scholar Rock Holding Corp | 1,961,965 | 96.5M $ | 1.30 % |
| 7 | Apogee Therapeutics Inc | 1,134,394 | 95.5M $ | 1.28 % |
| 8 | Protagonist Therapeutics Inc | 878,071 | 92.5M $ | 1.24 % |
| 9 | Summit Therapeutics Inc | 4,866,448 | 92.3M $ | 1.24 % |
| 10 | United Therapeutics Corp | 155,530 | 92.2M $ | 1.24 % |
| 11 | Praxis Precision Medicines Inc | 285,252 | 91.9M $ | 1.24 % |
| 12 | Arrowhead Pharmaceuticals Inc | 1,458,207 | 91.4M $ | 1.23 % |
| 13 | Cogent Biosciences Inc | 2,348,101 | 90.4M $ | 1.22 % |
| 14 | Bridgebio Pharma Inc | 1,186,816 | 88.1M $ | 1.19 % |
| 15 | PTC Therapeutics Inc | 1,290,071 | 87.9M $ | 1.18 % |
| 16 | Cytokinetics Inc | 1,331,453 | 87.8M $ | 1.18 % |
| 17 | Alnylam Pharmaceuticals Inc | 264,406 | 87.5M $ | 1.18 % |
| 18 | Exelixis Inc | 2,029,215 | 87M $ | 1.17 % |
| 19 | Nuvalent Inc | 846,768 | 86.8M $ | 1.17 % |
| 20 | Kymera Therapeutics Inc | 1,039,280 | 86.6M $ | 1.16 % |
| 21 | CG oncology Inc | 1,276,920 | 86.4M $ | 1.16 % |
| 22 | Natera Inc | 430,933 | 86.2M $ | 1.16 % |
| 23 | Neurocrine Biosciences Inc | 654,044 | 86.2M $ | 1.16 % |
| 24 | Twist Bioscience Corp | 1,808,036 | 85.9M $ | 1.16 % |
| 25 | Krystal Biotech Inc | 332,277 | 85.8M $ | 1.15 % |
| 26 | Vaxcyte Inc | 1,472,715 | 85.6M $ | 1.15 % |
| 27 | Mirum Pharmaceuticals Inc | 923,473 | 85.3M $ | 1.15 % |
| 28 | Amicus Therapeutics Inc | 5,895,670 | 85.3M $ | 1.15 % |
| 29 | Ionis Pharmaceuticals Inc | 1,132,906 | 85.1M $ | 1.14 % |
| 30 | Travere Therapeutics Inc | 2,863,192 | 85.1M $ | 1.14 % |
| 31 | Arcellx Inc | 740,785 | 85.1M $ | 1.14 % |
| 32 | Regeneron Pharmaceuticals, Inc. | 109,400 | 84.5M $ | 1.14 % |
| 33 | Incyte Corp | 895,013 | 84.2M $ | 1.13 % |
| 34 | Celcuity Inc | 731,925 | 83.5M $ | 1.12 % |
| 35 | Revolution Medicines Inc | 850,768 | 82.7M $ | 1.11 % |
| 36 | Halozyme Therapeutics Inc | 1,274,489 | 82.4M $ | 1.11 % |
| 37 | Rhythm Pharmaceuticals Inc | 941,162 | 81.9M $ | 1.10 % |
| 38 | Biogen Inc | 444,855 | 81.6M $ | 1.10 % |
| 39 | Arcutis Biotherapeutics Inc | 3,437,805 | 81M $ | 1.09 % |
| 40 | AbbVie Inc | 372,103 | 80.9M $ | 1.09 % |
| 41 | Gilead Sciences Inc | 580,264 | 80.9M $ | 1.09 % |
| 42 | CRISPR Therapeutics AG | 1,696,801 | 80.7M $ | 1.09 % |
| 43 | BioMarin Pharmaceutical Inc | 1,404,601 | 79.3M $ | 1.07 % |
| 44 | Roivant Sciences Ltd | 2,864,237 | 79.3M $ | 1.07 % |
| 45 | Amgen Inc | 224,546 | 79M $ | 1.06 % |
| 46 | ImmunityBio Inc | 10,244,025 | 78.6M $ | 1.06 % |
| 47 | Beam Therapeutics Inc | 3,248,626 | 77.4M $ | 1.04 % |
| 48 | Viking Therapeutics Inc | 2,369,189 | 77.1M $ | 1.04 % |
| 49 | Vera Therapeutics Inc | 1,912,054 | 76.9M $ | 1.03 % |
| 50 | Moderna Inc | 1,513,720 | 76.9M $ | 1.03 % |
| 51 | Vertex Pharmaceuticals Inc | 172,078 | 76.8M $ | 1.03 % |
| 52 | Erasca Inc | 4,733,094 | 76.6M $ | 1.03 % |
| 53 | ACADIA Pharmaceuticals Inc | 3,412,655 | 76M $ | 1.02 % |
| 54 | Sarepta Therapeutics Inc | 3,057,030 | 66.5M $ | 0.89 % |
| 55 | Agios Pharmaceuticals Inc | 1,930,324 | 65.3M $ | 0.88 % |
| 56 | Ultragenyx Pharmaceutical Inc | 3,107,837 | 65.1M $ | 0.88 % |
| 57 | Disc Medicine Inc | 1,012,048 | 64.7M $ | 0.87 % |
| 58 | Immunome Inc | 2,934,802 | 64.2M $ | 0.86 % |
| 59 | Immunovant Inc | 2,566,528 | 63.8M $ | 0.86 % |
| 60 | BioCryst Pharmaceuticals Inc | 6,655,054 | 63.4M $ | 0.85 % |
| 61 | Veracyte Inc | 1,957,681 | 63.1M $ | 0.85 % |
| 62 | Dyne Therapeutics Inc | 3,437,524 | 62.3M $ | 0.84 % |
| 63 | Catalyst Pharmaceuticals Inc | 2,268,292 | 56.2M $ | 0.76 % |
| 64 | Syndax Pharmaceuticals Inc | 2,343,191 | 54.7M $ | 0.74 % |
| 65 | Denali Therapeutics Inc | 2,830,854 | 54.4M $ | 0.73 % |
| 66 | Ideaya Biosciences Inc | 1,628,726 | 54.3M $ | 0.73 % |
| 67 | Spyre Therapeutics Inc | 1,069,556 | 53.9M $ | 0.73 % |
| 68 | GRAIL Inc | 1,041,295 | 53.8M $ | 0.72 % |
| 69 | Viridian Therapeutics Inc | 2,667,007 | 52.2M $ | 0.70 % |
| 70 | Recursion Pharmaceuticals Inc | 16,732,511 | 51.4M $ | 0.69 % |
| 71 | Kodiak Sciences Inc | 1,344,151 | 51.2M $ | 0.69 % |
| 72 | Soleno Therapeutics Inc | 1,496,078 | 50.1M $ | 0.67 % |
| 73 | Dianthus Therapeutics Inc | 586,673 | 49.2M $ | 0.66 % |
| 74 | Intellia Therapeutics Inc | 3,753,333 | 48.1M $ | 0.65 % |
| 75 | Mineralys Therapeutics Inc | 1,773,248 | 48M $ | 0.65 % |
| 76 | Arcus Biosciences Inc | 2,163,363 | 46.7M $ | 0.63 % |
| 77 | Ardelyx Inc | 7,664,448 | 45.9M $ | 0.62 % |
| 78 | ADMA Biologics Inc | 4,916,092 | 44.3M $ | 0.60 % |
| 79 | Nurix Therapeutics Inc | 2,809,877 | 43.6M $ | 0.59 % |
| 80 | Tango Therapeutics Inc | 1,972,571 | 41.3M $ | 0.56 % |
| 81 | Celldex Therapeutics Inc | 1,222,480 | 38.8M $ | 0.52 % |
| 82 | Novavax Inc | 4,667,715 | 38M $ | 0.51 % |
| 83 | Oruka Therapeutics Inc | 761,033 | 37.3M $ | 0.50 % |
| 84 | Olema Pharmaceuticals Inc | 2,471,879 | 36.9M $ | 0.50 % |
| 85 | Stoke Therapeutics Inc | 1,125,672 | 36.7M $ | 0.49 % |
| 86 | Vericel Corp | 1,116,252 | 35.9M $ | 0.48 % |
| 87 | Capricor Therapeutics Inc | 1,171,894 | 35.6M $ | 0.48 % |
| 88 | Palvella Therapeutics Inc | 274,232 | 34.2M $ | 0.46 % |
| 89 | Biohaven Ltd | 3,844,682 | 32.5M $ | 0.44 % |
| 90 | Monte Rosa Therapeutics Inc | 1,966,731 | 32.4M $ | 0.44 % |
| 91 | Corvus Pharmaceuticals Inc | 2,116,858 | 31M $ | 0.42 % |
| 92 | Iovance Biotherapeutics Inc | 8,139,873 | 28.6M $ | 0.38 % |
| 93 | AnaptysBio Inc | 512,175 | 28.4M $ | 0.38 % |
| 94 | Relay Therapeutics Inc | 2,831,639 | 28.2M $ | 0.38 % |
| 95 | uniQure NV | 1,697,402 | 27.8M $ | 0.37 % |
| 96 | ORIC Pharmaceuticals Inc | 2,171,512 | 27.5M $ | 0.37 % |
| 97 | MannKind Corp | 10,933,657 | 26.8M $ | 0.36 % |
| 98 | CareDx Inc | 1,480,419 | 25.7M $ | 0.35 % |
| 99 | Taysha Gene Therapies Inc | 5,638,911 | 25.2M $ | 0.34 % |
| 100 | Tyra Biosciences Inc | 655,457 | 25.1M $ | 0.34 % |
Sector breakdown
- Health care 14.8 %
- Unattributed 85.2 %
Titelia classification, company by company. The unattributed share stays visible.
Currency breakdown
- USD 100.0 %
The quoted currency of each line, as declared.
Country breakdown
- United States 95.4 %
- Ireland 1.6 %
- Switzerland 1.1 %
- Bermuda 1.1 %
- British Virgin Islands 0.4 %
- Netherlands 0.4 %
Shares computed on the equity sleeve.
| Rank | Country | Lines | Value | Share |
|---|---|---|---|---|
| 1 | United States | 141 | 7.1B $ | 95.45 % |
| 2 | Ireland | 2 | 117.4M $ | 1.58 % |
| 3 | Switzerland | 1 | 80.7M $ | 1.09 % |
| 4 | Bermuda | 1 | 79.3M $ | 1.07 % |
| 5 | British Virgin Islands | 1 | 32.5M $ | 0.44 % |
| 6 | Netherlands | 1 | 27.8M $ | 0.37 % |
Cite this page
Titelia. "Holdings of State Street(R) SPDR(R) S&P(R) Biotech ETF". https://titelia.com/en/funds/S000010018