Holdings of State Street(R) SPDR(R) S&P(R) Biotech ETF
SPDR SERIES TRUST · Original filing · Compare with another fund · Report an error
- Net assets
- 10.7B $ including 10.7B $ in equities, 99.9 %
- Positions
- 150 in 6 countries
- Top ten
- 13.3 % of net assets
- Filed on
- Jun 30, 2026
Portfolio shape
Positions
| Rank | Company | Shares | Value | Weight |
|---|---|---|---|---|
| 1 | Apogee Therapeutics Inc | 1,203,674 | 159.8M $ | 1.49 % |
| 2 | MODERNA INC | 2,164,892 | 151.6M $ | 1.41 % |
| 3 | TWIST BIOSCIENCE CORP | 1,469,111 | 151.1M $ | 1.41 % |
| 4 | ORUKA THERAPEUTICS INC | 1,555,002 | 148M $ | 1.38 % |
| 5 | KYMERA THERAPEUTICS INC | 1,272,754 | 145.9M $ | 1.36 % |
| 6 | Viking Therapeutics Inc | 3,587,998 | 140M $ | 1.30 % |
| 7 | Praxis Precision Medicines Inc | 413,737 | 138.5M $ | 1.29 % |
| 8 | Erasca Inc | 7,447,165 | 136.4M $ | 1.27 % |
| 9 | REVOLUTION MEDICINES INC | 690,499 | 129.3M $ | 1.20 % |
| 10 | Rhythm Pharmaceuticals Inc | 1,161,672 | 129M $ | 1.20 % |
| 11 | CG ONCOLOGY INC | 1,812,932 | 128.8M $ | 1.20 % |
| 12 | SELLAS Life Sciences Group Inc | 8,654,720 | 127.7M $ | 1.19 % |
| 13 | VAXCYTE INC | 2,192,112 | 127.4M $ | 1.19 % |
| 14 | Dianthus Therapeutics Inc | 1,302,913 | 127M $ | 1.18 % |
| 15 | CYTOKINETICS INC | 1,484,466 | 126.5M $ | 1.18 % |
| 16 | NATERA INC | 459,937 | 124.8M $ | 1.16 % |
| 17 | Scholar Rock Holding Corp | 2,258,236 | 124.2M $ | 1.16 % |
| 18 | Roivant Sciences Ltd | 3,504,648 | 124M $ | 1.16 % |
| 19 | MIRUM PHARMACEUTICALS INC | 1,059,206 | 124M $ | 1.16 % |
| 20 | COGENT BIOSCIENCES INC | 3,172,989 | 122.8M $ | 1.14 % |
| 21 | Ultragenyx Pharmaceutical Inc | 3,666,868 | 122.4M $ | 1.14 % |
| 22 | TRAVERE THERAPEUTICS INC | 2,130,135 | 121M $ | 1.13 % |
| 23 | Alkermes PLC | 2,271,185 | 119M $ | 1.11 % |
| 24 | Krystal Biotech Inc | 318,741 | 118.5M $ | 1.10 % |
| 25 | Celcuity Inc | 1,128,339 | 118M $ | 1.10 % |
| 26 | Relay Therapeutics Inc | 6,304,701 | 118M $ | 1.10 % |
| 27 | Spyre Therapeutics Inc | 1,326,035 | 117.7M $ | 1.10 % |
| 28 | TG THERAPEUTICS INC | 2,135,715 | 117.3M $ | 1.09 % |
| 29 | Beam Therapeutics Inc | 3,376,280 | 115.9M $ | 1.08 % |
| 30 | Insmed Inc | 1,083,724 | 115.5M $ | 1.08 % |
| 31 | Protagonist Therapeutics Inc | 941,367 | 115.4M $ | 1.07 % |
| 32 | Arrowhead Pharmaceuticals Inc | 1,407,587 | 114.7M $ | 1.07 % |
| 33 | VERA THERAPEUTICS INC | 2,650,187 | 113.7M $ | 1.06 % |
| 34 | Vertex Pharmaceuticals Inc | 228,475 | 113.5M $ | 1.06 % |
| 35 | Madrigal Pharmaceuticals Inc | 211,251 | 113.4M $ | 1.06 % |
| 36 | AbbVie Inc | 442,603 | 111.4M $ | 1.04 % |
| 37 | Biogen Inc | 512,556 | 110.7M $ | 1.03 % |
| 38 | PTC Therapeutics Inc | 1,357,466 | 110.7M $ | 1.03 % |
| 39 | Halozyme Therapeutics Inc | 1,412,358 | 110.5M $ | 1.03 % |
| 40 | uniQure NV | 2,396,361 | 110.4M $ | 1.03 % |
| 41 | Bridgebio Pharma Inc | 1,477,181 | 110M $ | 1.02 % |
| 42 | CRISPR Therapeutics AG | 2,013,860 | 109.8M $ | 1.02 % |
| 43 | IMMUNITYBIO INC | 12,496,050 | 109.4M $ | 1.02 % |
| 44 | Summit Therapeutics Inc | 7,453,137 | 108.6M $ | 1.01 % |
| 45 | IONIS PHARMACEUTICALS INC | 1,358,012 | 107.7M $ | 1.00 % |
| 46 | Incyte Corp | 944,922 | 107.1M $ | 1.00 % |
| 47 | Amgen Inc | 294,863 | 106.8M $ | 0.99 % |
| 48 | Neurocrine Biosciences Inc | 618,966 | 104.3M $ | 0.97 % |
| 49 | Gilead Sciences Inc | 819,573 | 103.5M $ | 0.96 % |
| 50 | Regeneron Pharmaceuticals Inc | 165,470 | 103.2M $ | 0.96 % |
| 51 | Exelixis Inc | 1,893,798 | 103M $ | 0.96 % |
| 52 | ALNYLAM PHARMACEUTICALS INC | 341,887 | 102.9M $ | 0.96 % |
| 53 | BioMarin Pharmaceutical Inc | 1,772,667 | 101.4M $ | 0.94 % |
| 54 | ACADIA Pharmaceuticals Inc | 3,977,187 | 100.6M $ | 0.94 % |
| 55 | Nuvalent Inc | 807,229 | 99.7M $ | 0.93 % |
| 56 | IMMUNOVANT INC | 2,576,556 | 99.3M $ | 0.92 % |
| 57 | United Therapeutics Corp | 183,055 | 99.2M $ | 0.92 % |
| 58 | Intellia Therapeutics Inc | 5,756,463 | 97.4M $ | 0.91 % |
| 59 | GRAIL Inc | 1,425,535 | 97.3M $ | 0.91 % |
| 60 | BioCryst Pharmaceuticals Inc | 9,581,829 | 95.8M $ | 0.89 % |
| 61 | Catalyst Pharmaceuticals Inc | 2,985,237 | 93.8M $ | 0.87 % |
| 62 | DYNE THERAPEUTICS INC | 4,152,258 | 92.2M $ | 0.86 % |
| 63 | Tango Therapeutics Inc | 2,891,041 | 90.4M $ | 0.84 % |
| 64 | Denali Therapeutics Inc | 3,475,517 | 89.4M $ | 0.83 % |
| 65 | Veracyte Inc | 1,496,464 | 87.9M $ | 0.82 % |
| 66 | Ideaya Biosciences Inc | 2,314,401 | 86.3M $ | 0.80 % |
| 67 | Recursion Pharmaceuticals Inc | 22,137,492 | 81.2M $ | 0.76 % |
| 68 | SAREPTA THERAPEUTICS INC | 4,460,837 | 80.2M $ | 0.75 % |
| 69 | ARCUS BIOSCIENCES INC | 2,587,788 | 79.8M $ | 0.74 % |
| 70 | Syndax Pharmaceuticals Inc | 3,528,047 | 77.1M $ | 0.72 % |
| 71 | Arcutis Biotherapeutics Inc | 2,914,129 | 76.4M $ | 0.71 % |
| 72 | Mineralys Therapeutics Inc | 2,820,768 | 76.1M $ | 0.71 % |
| 73 | Celldex Therapeutics Inc | 2,026,087 | 75.4M $ | 0.70 % |
| 74 | Agios Pharmaceuticals Inc | 2,005,301 | 74.4M $ | 0.69 % |
| 75 | VIRIDIAN THERAPEUTICS INC | 3,923,620 | 72.1M $ | 0.67 % |
| 76 | Novavax Inc | 7,529,392 | 70.9M $ | 0.66 % |
| 77 | Disc Medicine Inc | 958,601 | 70.1M $ | 0.65 % |
| 78 | ADMA Biologics Inc | 7,793,162 | 65.2M $ | 0.61 % |
| 79 | Immunome Inc | 2,991,978 | 63.4M $ | 0.59 % |
| 80 | PALVELLA THERAPEUTICS INC | 408,678 | 62.5M $ | 0.58 % |
| 81 | Iovance Biotherapeutics Inc | 14,493,812 | 60.3M $ | 0.56 % |
| 82 | Absci Corp | 5,171,464 | 59.9M $ | 0.56 % |
| 83 | Nurix Therapeutics Inc | 2,459,381 | 59.7M $ | 0.56 % |
| 84 | Kodiak Sciences Inc | 1,495,246 | 58.3M $ | 0.54 % |
| 85 | Biohaven Ltd | 3,790,861 | 56.4M $ | 0.53 % |
| 86 | Vericel Corp | 1,194,313 | 53.1M $ | 0.50 % |
| 87 | AnaptysBio Inc | 786,627 | 53.1M $ | 0.49 % |
| 88 | Capricor Therapeutics Inc | 2,178,269 | 52.5M $ | 0.49 % |
| 89 | Stoke Therapeutics Inc | 1,573,585 | 51.5M $ | 0.48 % |
| 90 | Monte Rosa Therapeutics Inc | 2,113,733 | 51.2M $ | 0.48 % |
| 91 | Vir Biotechnology Inc | 4,945,485 | 50.4M $ | 0.47 % |
| 92 | Hyperliquid Strategies Inc | 6,329,570 | 49.8M $ | 0.46 % |
| 93 | TYRA BIOSCIENCES INC | 1,392,376 | 44.5M $ | 0.41 % |
| 94 | Corvus Pharmaceuticals Inc | 2,931,644 | 43.8M $ | 0.41 % |
| 95 | Cullinan Therapeutics Inc | 2,377,645 | 43.3M $ | 0.40 % |
| 96 | Precigen Inc | 7,085,516 | 40.4M $ | 0.38 % |
| 97 | Inhibrx Biosciences Inc | 401,027 | 38M $ | 0.35 % |
| 98 | Taysha Gene Therapies Inc | 5,565,638 | 37.9M $ | 0.35 % |
| 99 | Ardelyx Inc | 7,416,791 | 37.8M $ | 0.35 % |
| 100 | AVALO THERAPEUTICS INC | 2,029,492 | 37.5M $ | 0.35 % |
Sector breakdown
- Health care 13.6 %
- Unattributed 86.4 %
Titelia assigns each company to a sector, one by one. The unassigned share stays visible, under "Unattributed".
Currency breakdown
- USD 100.0 %
Each line is counted in its quoted currency, as the fund declares it.
Country breakdown
- United States 95.0 %
- Ireland 1.2 %
- Bermuda 1.2 %
- Netherlands 1.0 %
- Switzerland 1.0 %
- British Virgin Islands 0.5 %
Shares are computed on the fund's equities only.
| Rank | Country | Lines | Value | Share |
|---|---|---|---|---|
| 1 | United States | 144 | 10.2B $ | 95.02 % |
| 2 | Ireland | 2 | 133.2M $ | 1.24 % |
| 3 | Bermuda | 1 | 124M $ | 1.16 % |
| 4 | Netherlands | 1 | 110.4M $ | 1.03 % |
| 5 | Switzerland | 1 | 109.8M $ | 1.02 % |
| 6 | British Virgin Islands | 1 | 56.4M $ | 0.53 % |
Cite this page
Titelia. "Holdings of State Street(R) SPDR(R) S&P(R) Biotech ETF". https://titelia.com/en/funds/S000010018