Funds holding Septerna Inc
ISIN US81734D1046 · United States
- Fund holders
- 172
- Of which ETFs
- 38 134 other funds
- Value held
- 221.4M $
- Share of capital
- 14.3 % of 46.7M shares on Aug 5, 2026
| Fund | Shares | Value | Weight in fund | Share of capital | |
|---|---|---|---|---|---|
| Victory Extended Market Index Fund Victory Portfolios III | 3,157 | 108.8K $ | 0.01 % | 0.01 % | as of Jul 31, 2026 ↗ |
| JNL/DFA U.S. Small Cap Fund JNL Series Trust | 3,015 | 101K $ | 0.01 % | 0.01 % | as of Jun 30, 2026 ↗ |
| HUSSMAN STRATEGIC ALLOCATION FUND Hussman Investment Trust | 3,000 | 100.5K $ | 0.42 % | 0.01 % | as of Jun 30, 2026 ↗ |
| BlackRock Small Cap Index V.I. Fund BlackRock Variable Series Funds, Inc. | 2,986 | 100K $ | 0.02 % | 0.01 % | as of Jun 30, 2026 ↗ |
| Dimensional US Core Equity Market ETF Dimensional ETF Trust | 2,955 | 101.8K $ | 0.00 % | 0.01 % | as of Jul 31, 2026 ↗ |
| Voya RussellTM Small Cap Index Portfolio Voya VARIABLE PORTFOLIOS INC | 2,797 | 93.7K $ | 0.02 % | 0.01 % | as of Jun 30, 2026 ↗ |
| SA Small Cap Index Portfolio SUNAMERICA SERIES TRUST | 2,382 | 82.1K $ | 0.02 % | 0.01 % | as of Jul 31, 2026 ↗ |
| Invesco Nasdaq Biotechnology ETF Invesco Exchange-Traded Fund Trust II | 2,373 | 71.7K $ | 0.11 % | 0.01 % | as of May 31, 2026 ↗ |
| Venerable US Small Cap Fund Venerable Variable Insurance Trust | 2,247 | 75.3K $ | 0.05 % | 0.00 % | as of Jun 30, 2026 ↗ |
| Federated Hermes Global Allocation Fund Federated Hermes Global Allocation Fund | 2,244 | 67.8K $ | 0.02 % | 0.00 % | as of May 31, 2026 ↗ |
| EQ/Morgan Stanley Small Cap Growth Portfolio EQ Advisors Trust | 2,240 | 75K $ | 0.02 % | 0.00 % | as of Jun 30, 2026 ↗ |
| PGIM Quant Solutions Small-Cap Value Fund Target Portfolio Trust | 2,200 | 75.8K $ | 0.02 % | 0.00 % | as of Jul 31, 2026 ↗ |
| U.S. Social Core Equity 2 Portfolio DFA INVESTMENT DIMENSIONS GROUP INC | 2,183 | 75.2K $ | 0.00 % | 0.00 % | as of Jul 31, 2026 ↗ |
| CVT Russell 2000 Small Cap Index Portfolio Calvert Variable Trust, Inc. | 1,944 | 65.1K $ | 0.02 % | 0.00 % | as of Jun 30, 2026 ↗ |
| Nationwide Small Cap Index Fund Nationwide Mutual Funds | 1,901 | 65.5K $ | 0.02 % | 0.00 % | as of Jul 31, 2026 ↗ |
| VIP Extended Market Index Portfolio Variable Insurance Products Fund II | 1,870 | 62.6K $ | 0.01 % | 0.00 % | as of Jun 30, 2026 ↗ |
| PHARMACEUTICALS ULTRASECTOR PROFUND ProFunds | 1,779 | 61.3K $ | 0.71 % | 0.00 % | as of Jul 31, 2026 ↗ |
| Venerable Small Cap Index Fund Venerable Variable Insurance Trust | 1,768 | 59.2K $ | 0.02 % | 0.00 % | as of Jun 30, 2026 ↗ |
| iShares Total U.S. Stock Market Index Fund BlackRock Funds | 1,749 | 60.3K $ | 0.00 % | 0.00 % | as of Jul 31, 2026 ↗ |
| MFS Blended Research Small Cap Equity Portfolio MFS VARIABLE INSURANCE TRUST III | 1,688 | 56.5K $ | 0.07 % | 0.00 % | as of Jun 30, 2026 ↗ |
| Longboard Fund NORTHERN LIGHTS FUND TRUST II | 1,660 | 50.1K $ | 0.05 % | 0.00 % | as of May 31, 2026 ↗ |
| ProShares Ultra Nasdaq Biotechnology ProShares Trust | 1,657 | 50K $ | 0.07 % | 0.00 % | as of May 31, 2026 ↗ |
| Royce Quant Small-Cap Quality Value ETF Legg Mason ETF Investment Trust | 1,547 | 51.8K $ | 0.18 % | 0.00 % | as of Jun 30, 2026 ↗ |
| Voya VACS Index Series SC Portfolio Voya VARIABLE PORTFOLIOS INC | 1,523 | 51K $ | 0.02 % | 0.00 % | as of Jun 30, 2026 ↗ |
| VANGUARD RUSSELL 3000 INDEX FUND VANGUARD SCOTTSDALE FUNDS | 1,508 | 45.5K $ | 0.00 % | 0.00 % | as of May 31, 2026 ↗ |
| PD Small-Cap Growth Index Portfolio PACIFIC SELECT FUND | 1,350 | 45.2K $ | 0.03 % | 0.00 % | as of Jun 30, 2026 ↗ |
| SmallCap Growth Fund I Principal Funds, Inc | 1,275 | 43.9K $ | 0.00 % | 0.00 % | as of Jul 31, 2026 ↗ |
| U.S. Small Cap Equity Fund RUSSELL INVESTMENT CO | 1,221 | 42.1K $ | 0.00 % | 0.00 % | as of Jul 31, 2026 ↗ |
| 1290 VT Small Cap Value Portfolio EQ Advisors Trust | 1,180 | 39.5K $ | 0.01 % | 0.00 % | as of Jun 30, 2026 ↗ |
| U.S. Small Cap Equity Fund RUSSELL INVESTMENT FUNDS | 1,027 | 34.4K $ | 0.01 % | 0.00 % | as of Jun 30, 2026 ↗ |
| ProShares Russell 2000 High Income ETF ProShares Trust | 1,006 | 30.4K $ | 0.02 % | 0.00 % | as of May 31, 2026 ↗ |
| VANGUARD GROWTH AND INCOME FUND VANGUARD QUANTITATIVE FUNDS | 1,000 | 33.5K $ | 0.00 % | 0.00 % | as of Jun 30, 2026 ↗ |
| Strategic Equity Allocation Trust John Hancock Variable Insurance Trust | 984 | 33K $ | 0.00 % | 0.00 % | as of Jun 30, 2026 ↗ |
| Gotham Enhanced Return Fund FundVantage Trust | 952 | 31.9K $ | 0.01 % | 0.00 % | as of Jun 30, 2026 ↗ |
| iShares Morningstar Small-Cap ETF iShares Trust | 906 | 31.2K $ | 0.01 % | 0.00 % | as of Jul 31, 2026 ↗ |
| PD Small-Cap Value Index Portfolio PACIFIC SELECT FUND | 815 | 27.3K $ | 0.02 % | 0.00 % | as of Jun 30, 2026 ↗ |
| ProShares UltraPro Russell2000 ProShares Trust | 797 | 24.1K $ | 0.01 % | 0.00 % | as of May 31, 2026 ↗ |
| ProShares Ultra Russell2000 ProShares Trust | 787 | 23.8K $ | 0.01 % | 0.00 % | as of May 31, 2026 ↗ |
| EQ/Franklin Small Cap Value Managed Volatility Portfolio EQ Advisors Trust | 774 | 25.9K $ | 0.01 % | 0.00 % | as of Jun 30, 2026 ↗ |
| Total Stock Market Index Trust John Hancock Variable Insurance Trust | 724 | 24.2K $ | 0.00 % | 0.00 % | as of Jun 30, 2026 ↗ |
| Morgan Stanley Pathway Small-Mid Cap Equity ETF MORGAN STANLEY PATHWAY FUNDS | 675 | 20.4K $ | 0.00 % | 0.00 % | as of May 31, 2026 ↗ |
| Avantis U.S. Equity ETF American Century ETF Trust | 672 | 20.3K $ | 0.00 % | 0.00 % | as of May 31, 2026 ↗ |
| Penn Series Small Cap Index Fund Penn Series Funds Inc | 600 | 20.1K $ | 0.02 % | 0.00 % | as of Jun 30, 2026 ↗ |
| VIP Total Market Index Portfolio Variable Insurance Products Fund II | 581 | 19.5K $ | 0.00 % | 0.00 % | as of Jun 30, 2026 ↗ |
| State Street Total Return V.I.S. Fund STATE STREET VARIABLE INSURANCE SERIES FUNDS INC | 559 | 18.7K $ | 0.00 % | 0.00 % | as of Jun 30, 2026 ↗ |
| SmallCap Value Fund II Principal Funds, Inc | 552 | 19K $ | 0.00 % | 0.00 % | as of Jul 31, 2026 ↗ |
| Nationwide Fundamental All Cap Equity Portfolio Nationwide Mutual Funds | 515 | 17.7K $ | 0.00 % | 0.00 % | as of Jul 31, 2026 ↗ |
| Virtus AlphaSimplex Global Alternatives Fund Virtus Alternative Solutions Trust | 476 | 15.9K $ | 0.02 % | 0.00 % | as of Jun 30, 2026 ↗ |
| Fidelity Flex Small Cap Focused Index Fund Fidelity Salem Street Trust | 447 | 15.4K $ | 0.09 % | 0.00 % | as of Jul 31, 2026 ↗ |
| Gotham Neutral Fund FundVantage Trust | 445 | 14.9K $ | 0.01 % | 0.00 % | as of Jun 30, 2026 ↗ |
| Small-Cap Equity Portfolio PACIFIC SELECT FUND | 444 | 14.9K $ | 0.00 % | 0.00 % | as of Jun 30, 2026 ↗ |
| TIAA Separate Account VA-1 - Stock Index Account TIAA Separate Account VA-1 | 421 | 14.1K $ | 0.00 % | 0.00 % | as of Jun 30, 2026 ↗ |
| Dimensional US Core Equity 1 ETF Dimensional ETF Trust | 418 | 14.4K $ | 0.00 % | 0.00 % | as of Jul 31, 2026 ↗ |
| SA U.S. Small Company Fund SA FUNDS INVESTMENT TRUST | 410 | 13.7K $ | 0.00 % | 0.00 % | as of Jun 30, 2026 ↗ |
| Avantis U.S. Equity Fund American Century ETF Trust | 375 | 11.3K $ | 0.00 % | 0.00 % | as of May 31, 2026 ↗ |
| Nuveen Life Stock Index Fund TIAA-CREF Life Funds | 297 | 9.9K $ | 0.00 % | 0.00 % | as of Jun 30, 2026 ↗ |
| ULTRA SMALL CAP PROFUND ProFunds | 285 | 9.8K $ | 0.02 % | 0.00 % | as of Jul 31, 2026 ↗ |
| Blackstone Alternative Multi-Strategy Fund Blackstone Alternative Investment Funds | 200 | 6.7K $ | 0.00 % | 0.00 % | as of Jun 30, 2026 ↗ |
| Knights of Columbus U.S. ALL CAP INDEX FUND ADVISORS' INNER CIRCLE III | 171 | 5.9K $ | 0.00 % | 0.00 % | as of Jul 31, 2026 ↗ |
| State Street Balanced Index Fund STATE STREET INSTITUTIONAL INVESTMENT TRUST | 147 | 4.9K $ | 0.00 % | 0.00 % | as of Jun 30, 2026 ↗ |
| Russell 2000 2x Strategy Fund Rydex Dynamic Funds | 119 | 4K $ | 0.01 % | 0.00 % | as of Jun 30, 2026 ↗ |
| PROFUND VP ULTRA SMALL CAP ProFunds | 91 | 3K $ | 0.01 % | 0.00 % | as of Jun 30, 2026 ↗ |
| Dimensional U.S. Equity Market ETF Dimensional ETF Trust | 72 | 2.5K $ | 0.00 % | as of Jul 31, 2026 ↗ | |
| Avantis Total Equity Markets ETF American Century ETF Trust | 71 | 2.1K $ | 0.00 % | 0.00 % | as of May 31, 2026 ↗ |
| PROFUND VP SMALL CAP ProFunds | 59 | 2K $ | 0.02 % | 0.00 % | as of Jun 30, 2026 ↗ |
| Russell 2000 Fund Rydex Series Funds | 55 | 1.8K $ | 0.01 % | 0.00 % | as of Jun 30, 2026 ↗ |
| Columbia Research Enhanced Small Cap ETF Columbia ETF Trust I | 47 | 1.6K $ | 0.04 % | 0.00 % | as of Jun 30, 2026 ↗ |
| Russell 2000 1.5x Strategy Fund Rydex Series Funds | 33 | 1.1K $ | 0.02 % | 0.00 % | as of Jun 30, 2026 ↗ |
| ProShares Hedge Replication ETF ProShares Trust | 20 | 604 $ | 0.00 % | 0.00 % | as of May 31, 2026 ↗ |
| SMALL-CAP PROFUND ProFunds | 19 | 654.6 $ | 0.01 % | 0.00 % | as of Jul 31, 2026 ↗ |
| Russell 2000(R) 1.5x Strategy Fund Rydex Variable Trust | 6 | 200.9 $ | 0.00 % | 0.00 % | as of Jun 30, 2026 ↗ |
| ProShares Russell 2000 Dynamic Buffer ETF ProShares Trust | 6 | 181.2 $ | 0.02 % | 0.00 % | as of May 31, 2026 ↗ |
The funds most exposed to it
The weight is the share of a fund's net assets. The holders table ranks funds by number of shares. This one ranks them by the weight of the company in each fund.
| Fund | Weight in fund | |
|---|---|---|
| State Street(R) SPDR(R) S&P(R) Pharmaceuticals ETF SPDR SERIES TRUST | 0.99 % | as of Jun 30, 2026 ↗ |
| PROFUND VP PHARMACEUTICALS ProFunds | 0.96 % | as of Jun 30, 2026 ↗ |
| Driehaus Micro Cap Growth Fund Driehaus Mutual Funds | 0.89 % | as of Jun 30, 2026 ↗ |
| Driehaus Small Cap Growth Fund Driehaus Mutual Funds | 0.87 % | as of Jun 30, 2026 ↗ |
| Direxion Daily Pharmaceutical & Medical Bull 3X Shares Direxion Shares ETF Trust | 0.76 % | as of Jul 31, 2026 ↗ |
| PHARMACEUTICALS ULTRASECTOR PROFUND ProFunds | 0.71 % | as of Jul 31, 2026 ↗ |
| Virtus Biotech Clinical Trials Etf ETFis Series Trust I | 0.64 % | as of Jul 31, 2026 ↗ |
| HUSSMAN STRATEGIC MARKET CYCLE FUND Hussman Investment Trust | 0.57 % | as of Jun 30, 2026 ↗ |
| Loomis Sayles Small Cap Growth Portfolio Brighthouse Funds Trust II | 0.50 % | as of Jun 30, 2026 ↗ |
| Loomis Sayles Small Cap Growth Fund LOOMIS SAYLES FUNDS II | 0.50 % | as of Jun 30, 2026 ↗ |
Quarter after quarter
Each row is one quarter of SEC filings, newest first. The change compares each quarter with the one before.
| Quarter | Holders | Change | Shares | Change |
|---|---|---|---|---|
| 2026Q3 | 172 | +22 | 6,677,788 | +12.5 % |
| 2026Q2 | 150 | +23 | 5,935,202 | +4.7 % |
| 2026Q1 | 127 | +34 | 5,668,379 | +33.8 % |
| 2025Q4 | 93 | +3 | 4,237,151 | -2.1 % |
| 2025Q3 | 90 | -1 | 4,326,042 | +33.6 % |
| 2025Q2 | 91 | -4 | 3,238,852 | -8.1 % |
| 2025Q1 | 95 | +92 | 3,524,626 | +2,138.0 % |
| 2024Q4 | 3 | 157,492 |
Institutional managers
118 managers declare this company to the SEC (Form 13F). The table shows the 25 largest.
| Manager | Shares | Value | |
|---|---|---|---|
| RA CAPITAL MANAGEMENT, L.P. | 6,995,858 | 168.1M $ | as of Mar 31, 2026 |
| TRV GP V, LLC | 6,215,591 | 149.4M $ | as of Mar 31, 2026 |
| Driehaus Capital Management LLC | 4,395,572 | 105.6M $ | as of Mar 31, 2026 |
| TRV GP VI, LLC | 4,211,659 | 101.2M $ | as of Mar 31, 2026 |
| SAMSARA BIOCAPITAL, LLC | 3,149,128 | 75.7M $ | as of Mar 31, 2026 |
| GOLDMAN SACHS GROUP INC | 2,906,427 | 69.8M $ | as of Mar 31, 2026 |
| Siren, L.L.C. | 2,000,000 | 48.1M $ | as of Mar 31, 2026 |
| BlackRock, Inc. | 1,822,174 | 43.8M $ | as of Mar 31, 2026 |
| BVF INC/IL | 1,353,249 | 32.5M $ | as of Mar 31, 2026 |
| Avoro Capital Advisors LLC | 1,337,500 | 32.1M $ | as of Mar 31, 2026 |
| ADAR1 Capital Management, LLC | 1,089,818 | 26.2M $ | as of Mar 31, 2026 |
| PRIMECAP MANAGEMENT CO/CA/ | 1,048,834 | 25.2M $ | as of Mar 31, 2026 |
| JANUS HENDERSON GROUP PLC | 890,754 | 21.3M $ | as of Mar 31, 2026 |
| First Light Asset Management, LLC | 732,860 | 17.6M $ | as of Mar 31, 2026 |
| GEODE CAPITAL MANAGEMENT, LLC | 645,146 | 15.5M $ | as of Mar 31, 2026 |
| STATE STREET CORP | 631,447 | 15.2M $ | as of Mar 31, 2026 |
| Casdin Capital, LLC | 553,268 | 13.3M $ | as of Mar 31, 2026 |
| Venrock Adviser, LLC | 506,056 | 12.2M $ | as of Mar 31, 2026 |
| Catalio Capital Management, LP | 294,360 | 7.1M $ | as of Mar 31, 2026 |
| Soleus Capital Management, L.P. | 275,000 | 6.6M $ | as of Mar 31, 2026 |
| Balyasny Asset Management L.P. | 236,679 | 5.7M $ | as of Mar 31, 2026 |
| Universal- Beteiligungs- und Servicegesellschaft mbH | 223,995 | 5.4M $ | as of Mar 31, 2026 |
| Kalehua Capital Management LLC | 194,544 | 4.7M $ | as of Mar 31, 2026 |
| CHARLES SCHWAB INVESTMENT MANAGEMENT INC | 181,580 | 4.4M $ | as of Mar 31, 2026 |
| NORTHERN TRUST CORP | 164,530 | 4M $ | as of Mar 31, 2026 |
Declared shareholders of Septerna Inc
There are 2 beneficial ownership filings. These stakes do not add up. An asset manager that files includes its own funds, which already appear among the funds on this page.
| Shareholder | Declared stake | Shares | |
|---|---|---|---|
| RA Capital Management, L.P. and 3 others | 11.80 % | 5,525,324 | as of Aug 12, 2026 · SCHEDULE 13D |
| DRIEHAUS CAPITAL MANAGEMENT LLC | 9.83 % | 4,433,058 | as of Jun 30, 2026 · SCHEDULE 13G |
Cite this page
Titelia. "Funds holding Septerna Inc". https://titelia.com/en/stocks/septerna-inc-US81734D1046