Titelia

Holdings of Siren, L.L.C.

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Net assets
-
Positions
85 in 6 countries
Top ten
53.5 % of the equity sleeve
Filed on
Mar 31, 2026
Portfolio shape

Positions

RankCompanySharesValueWeight
1Scholar Rock Holding Corp 10,825,013532.2M $
2KYMERA THERAPEUTICS INC 3,186,830265.4M $
3Erasca Inc 11,244,246181.9M $
4Edgewise Therapeutics Inc 4,430,263139.6M $
5BEONE MEDICINES LTD 465,000138.1M $
6Tango Therapeutics Inc 5,657,105118.3M $
7Bicara Therapeutics Inc 5,802,970115.4M $
8REVOLUTION MEDICINES INC 1,110,980108M $
9Arrowhead Pharmaceuticals Inc 1,615,476101.3M $
10VERADERMICS INC 1,505,37495.1M $
11Olema Pharmaceuticals Inc 4,756,94970.9M $
12Crinetics Pharmaceuticals Inc 1,903,63669.1M $
13LEXICON PHARMACEUTICALS INC 44,303,51869.1M $
14COGENT BIOSCIENCES INC 1,709,27965.8M $
15Stoke Therapeutics Inc 1,995,34765M $
16ARCUS BIOSCIENCES INC 3,007,07765M $
17STRUCTURE THERAPEUTICS INC 1,328,69864M $
18Disc Medicine Inc 988,40163.2M $
19Rhythm Pharmaceuticals Inc 725,51163.1M $
20Solid Biosciences Inc 7,690,40555.4M $
21Septerna Inc 2,000,00048.1M $
22Centessa Pharmaceuticals PLC 1,053,46441.8M $
23Spyre Therapeutics Inc 818,59841.3M $
24CYTOKINETICS INC 613,95240.5M $
25DYNE THERAPEUTICS INC 2,229,12540.4M $
26Taysha Gene Therapies Inc 8,829,91339.5M $
27DBV Technologies SA 1,857,36238.8M $
28ORIC Pharmaceuticals Inc 2,998,19238M $
29PALVELLA THERAPEUTICS INC 257,48532.1M $
30Enliven Therapeutics Inc 746,22629.3M $
31Denali Therapeutics Inc 1,396,51326.8M $
32Remitly Global Inc 1,543,27124.2M $
33DAMORA THERAPEUTICS INC 900,00023.3M $
34Annexon Inc 3,958,64621.9M $
35Trevi Therapeutics Inc 1,786,86721.3M $
36Rapport Therapeutics Inc 641,46920.1M $
37Alphabet Inc 65,70318.9M $
38FULCRUM THERAPEUTICS INC 2,350,00018M $
39AMYLYX PHARMACEUTICALS INC 1,230,00017.1M $
40Cullinan Therapeutics Inc 1,193,41017M $
41Neumora Therapeutics Inc 8,497,82216.6M $
42CYTOMX THERAPEUTICS INC 3,457,71116.3M $
43NVIDIA Corp 89,08515.5M $
44SILENCE THERAPEUTICS PLC 2,911,43815.3M $
45Microsoft Corp 41,38015.3M $
46Monopar Therapeutics Inc 270,11814.8M $
47Taiwan Semiconductor Manufacturing Co Ltd 42,20014.3M $
48Sionna Therapeutics Inc 300,00012M $
49Rezolute Inc 3,328,28710.2M $
50Inhibikase Therapeutics Inc 5,850,0009.8M $
51Amazon.com Inc 46,6419.7M $
52Generate Biomedicines Inc 736,1049.2M $
53MAPLIGHT THERAPEUTICS INC 450,0009.1M $
54ServiceNow Inc 87,0909.1M $
55Crowdstrike Holdings Inc 23,0709M $
56PDD Holdings Inc 83,4018.5M $
57Tesla Inc 21,5008M $
58NovaBridge Biosciences 3,000,0007.4M $
59BICYCLE THERAPEUTICS PLC 1,560,8827.2M $
60Whitehawk Therapeutics Inc 2,082,0007.2M $
61Tenax Therapeutics Inc 427,1416.8M $
62vTv Therapeutics Inc 163,0006.5M $
63Datadog Inc 54,3006.4M $
64Dynatrace Inc 150,0005.5M $
65Workiva Inc 92,5005.5M $
66Absci Corp 1,800,0005.4M $
67Invivyd Inc 4,000,0005.2M $
68IonQ Inc 170,0004.9M $
69Broadcom Inc 15,0004.6M $
70AGOMAB THERAPEUTICS SA 411,2504.3M $
71Seer Inc 2,458,6734.1M $
72Korro Bio Inc 347,7183.9M $
73Agenus Inc 1,064,2503.6M $
74Foghorn Therapeutics Inc 720,7203.4M $
75Forgent Power Solutions Inc 100,0002.9M $
76Kalaris Therapeutics Inc 435,7982.5M $
77Gitlab Inc 100,0002.2M $
78Micron Technology Inc 6,0002M $
79Gossamer Bio Inc 5,208,9681.7M $
80KE Holdings Inc 100,0001.5M $
81RANI THERAPEUTICS HOLDINGS INC 2,000,0001.5M $
82Aeva Technologies Inc 110,0001.4M $
83Medline Inc 25,0001.1M $
84FIGMA INC 50,0001.1M $
85Primo Brands Corp 50,000941.5K $

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Sector breakdown

  • Technology 2.3 %
  • Consumer discretionary 0.8 %
  • Communication 0.6 %
  • Unattributed 96.4 %

Titelia assigns each company to a sector, one by one. The unassigned share stays visible, under "Unattributed".

Currency breakdown

  • USD 100.0 %

Each line is counted in its quoted currency, as the fund declares it.

Country breakdown

  • United States 95.9 %
  • United Kingdom 1.9 %
  • France 1.2 %
  • Cayman Islands 0.5 %
  • Taiwan 0.4 %
  • Belgium 0.1 %

Shares are computed on the fund's equities only.

RankCountryLinesValueShare
1United States763.2B $95.85 %
2United Kingdom364.4M $1.92 %
3France138.8M $1.16 %
4Cayman Islands317.4M $0.52 %
5Taiwan114.3M $0.42 %
6Belgium14.3M $0.13 %
Cite this page

Titelia. "Holdings of Siren, L.L.C.". https://titelia.com/en/funds/US13F2005245