| 1 | Abivax SA | 1,394,019 | 155.2M $ | |
| 2 | Protagonist Therapeutics Inc | 994,119 | 104.8M $ | |
| 3 | Immunovant Inc | 2,679,010 | 66.5M $ | |
| 4 | State Street SPDR S&P 500 ETF Trust | 75,940 | 49.4M $ | |
| 5 | Terns Pharmaceuticals Inc | 914,699 | 48.2M $ | |
| 6 | Cytokinetics Inc | 632,556 | 41.7M $ | |
| 7 | Crinetics Pharmaceuticals Inc | 1,139,331 | 41.4M $ | |
| 8 | Alpha Architect 1-3 Month Box | 337,125 | 39.2M $ | |
| 9 | Denali Therapeutics Inc | 1,871,455 | 35.9M $ | |
| 10 | Beam Therapeutics Inc | 1,446,375 | 34.5M $ | |
| 11 | ZAI LAB LTD | 1,425,367 | 26.8M $ | |
| 12 | Septerna Inc | 1,089,818 | 26.2M $ | |
| 13 | Vir Biotechnology Inc | 2,744,714 | 24.6M $ | |
| 14 | DBV Technologies SA | 1,012,866 | 21.2M $ | |
| 15 | Anteris Technologies Global Corp | 3,789,132 | 21M $ | |
| 16 | Inspire Medical Systems Inc | 405,197 | 20.9M $ | |
| 17 | Scholar Rock Holding Corp | 407,273 | 20M $ | |
| 18 | Rhythm Pharmaceuticals Inc | 211,450 | 18.4M $ | |
| 19 | Spyre Therapeutics Inc | 338,323 | 17.1M $ | |
| 20 | CytomX Therapeutics Inc | 3,410,190 | 16M $ | |
| 21 | Sanofi SA | 316,939 | 15.3M $ | |
| 22 | Vaxcyte Inc | 259,137 | 15.1M $ | |
| 23 | Monopar Therapeutics Inc | 264,278 | 14.5M $ | |
| 24 | Amylyx Pharmaceuticals Inc | 1,000,604 | 13.9M $ | |
| 25 | Celldex Therapeutics Inc | 427,816 | 13.6M $ | |
| 26 | Taysha Gene Therapies Inc | 2,979,429 | 13.3M $ | |
| 27 | Sutro Biopharma Inc | 524,441 | 13.1M $ | |
| 28 | Revolution Medicines Inc | 133,893 | 13M $ | |
| 29 | Enliven Therapeutics Inc | 329,540 | 12.9M $ | |
| 30 | CG oncology Inc | 185,699 | 12.6M $ | |
| 31 | SPDR Series Trust | 135,585 | 12.4M $ | |
| 32 | Replimune Group Inc | 1,582,987 | 12.1M $ | |
| 33 | Inventiva SACA | 2,174,398 | 12.1M $ | |
| 34 | Ionis Pharmaceuticals Inc | 160,338 | 12M $ | |
| 35 | Nektar Therapeutics | 161,252 | 11.6M $ | |
| 36 | Inhibikase Therapeutics Inc | 6,606,572 | 11.1M $ | |
| 37 | ARS Pharmaceuticals Inc | 1,361,536 | 10.9M $ | |
| 38 | Ovid therapeutics Inc | 4,544,113 | 10.1M $ | |
| 39 | OnKure Therapeutics Inc | 2,434,941 | 10.1M $ | |
| 40 | Regeneron Pharmaceuticals, Inc. | 12,154 | 9.4M $ | |
| 41 | Lexeo Therapeutics Inc | 1,467,350 | 8.4M $ | |
| 42 | Opus Genetics Inc | 1,849,004 | 8.4M $ | |
| 43 | Teva Pharmaceutical Industries Ltd | 268,391 | 8.1M $ | |
| 44 | Savara Inc | 1,464,535 | 8M $ | |
| 45 | MapLight Therapeutics Inc | 374,909 | 7.6M $ | |
| 46 | LeonaBio Inc | 727,481 | 7.5M $ | |
| 47 | Equillium Inc | 3,726,659 | 7.5M $ | |
| 48 | Viking Therapeutics Inc | 227,717 | 7.4M $ | |
| 49 | DAMORA THERAPEUTICS INC | 279,000 | 7.2M $ | |
| 50 | Bridgebio Pharma Inc | 94,292 | 7M $ | |
| 51 | Prime Medicine Inc | 1,973,282 | 6.9M $ | |
| 52 | Vertex Pharmaceuticals Inc | 15,075 | 6.7M $ | |
| 53 | Korro Bio Inc | 540,054 | 6.1M $ | |
| 54 | Viridian Therapeutics Inc | 304,422 | 6M $ | |
| 55 | Danaher Corp | 30,932 | 5.9M $ | |
| 56 | Insmed Inc | 35,392 | 5.8M $ | |
| 57 | Ascendis Pharma A/S | 25,014 | 5.7M $ | |
| 58 | Brighthouse Financial Inc | 95,523 | 5.7M $ | |
| 59 | Sarepta Therapeutics Inc | 262,058 | 5.7M $ | |
| 60 | Krystal Biotech Inc | 20,014 | 5.2M $ | |
| 61 | Acumen Pharmaceuticals Inc | 2,156,334 | 5.1M $ | |
| 62 | Invivyd Inc | 3,822,427 | 5M $ | |
| 63 | Protara Therapeutics Inc | 940,512 | 4.9M $ | |
| 64 | Agios Pharmaceuticals Inc | 140,672 | 4.8M $ | |
| 65 | Eli Lilly & Co | 5,060 | 4.7M $ | |
| 66 | Dianthus Therapeutics Inc | 55,000 | 4.6M $ | |
| 67 | Arrowhead Pharmaceuticals Inc | 70,300 | 4.4M $ | |
| 68 | Belite Bio Inc | 26,880 | 4.3M $ | |
| 69 | Evommune Inc | 184,062 | 4.2M $ | |
| 70 | Mineralys Therapeutics Inc | 154,686 | 4.2M $ | |
| 71 | Janux Therapeutics Inc | 298,546 | 4.1M $ | |
| 72 | Climb Bio Inc | 597,662 | 4.1M $ | |
| 73 | Palisade Bio Inc | 2,264,845 | 4M $ | |
| 74 | SPRUCE BIOSCIENCES INC | 58,600 | 3.8M $ | |
| 75 | Arcellx Inc | 32,084 | 3.7M $ | |
| 76 | Contineum Therapeutics Inc | 276,661 | 3.6M $ | |
| 77 | Monte Rosa Therapeutics Inc | 215,752 | 3.5M $ | |
| 78 | BEONE MEDICINES LTD | 11,701 | 3.5M $ | |
| 79 | Tenax Therapeutics Inc | 213,462 | 3.4M $ | |
| 80 | ArriVent Biopharma Inc | 141,814 | 3.3M $ | |
| 81 | Pliant Therapeutics Inc | 2,585,126 | 3.3M $ | |
| 82 | AtaiBeckley Inc | 913,242 | 3.2M $ | |
| 83 | Relmada Therapeutics Inc | 451,918 | 3.1M $ | |
| 84 | Perspective Therapeutics Inc | 749,335 | 3.1M $ | |
| 85 | Corbus Pharmaceuticals Holdings Inc | 331,781 | 3.1M $ | |
| 86 | Eledon Pharmaceuticals Inc | 974,421 | 3M $ | |
| 87 | Apellis Pharmaceuticals Inc | 72,500 | 2.9M $ | |
| 88 | Edgewise Therapeutics Inc | 90,599 | 2.9M $ | |
| 89 | PepGen Inc | 1,607,638 | 2.8M $ | |
| 90 | Capricor Therapeutics Inc | 90,593 | 2.8M $ | |
| 91 | Masimo Corp | 15,000 | 2.7M $ | |
| 92 | INOVIO PHARMACEUTICALS INC | 1,470,108 | 2.6M $ | |
| 93 | Teleflex Inc | 21,186 | 2.5M $ | |
| 94 | BioAge Labs Inc | 135,560 | 2.4M $ | |
| 95 | Alector Inc | 1,050,000 | 2.3M $ | |
| 96 | Pfizer Inc | 77,400 | 2.2M $ | |
| 97 | Delcath Systems Inc | 224,385 | 2.1M $ | |
| 98 | Biogen Inc | 11,000 | 2M $ | |
| 99 | Summit Therapeutics Inc | 91,869 | 1.7M $ | |
| 100 | Globus Medical Inc | 20,100 | 1.7M $ | |