Titelia

Fund shareholders of KARYOPHARM THERAPEUTICS INC

ISIN US48576U2050 · United States · LEI 549300J1VANRCNTYST87

Fund shareholders
79
Of which ETFs
10 69 other funds
Value held
26.8M $
Share of capital
13.4 % of 22.7M shares on Aug 6, 2026
Sold short
0.5 % by 1 fund, as of Aug 20, 2026
FundSharesValueWeight in fundShare of capital
VANGUARD TOTAL STOCK MARKET INDEX FUND VANGUARD INDEX FUNDS 677,7296.6M $0.00 %2.99 %as of Jun 30, 2026 ↗
iShares Russell 2000 ETF iShares Trust 490,3174.8M $0.01 %2.16 %as of Jun 30, 2026 ↗
T. Rowe Price Small-Cap Value Fund, Inc. T. ROWE PRICE SMALL-CAP VALUE FUND, INC. 435,0704.3M $0.04 %1.92 %as of Jun 30, 2026 ↗
VANGUARD EXTENDED MARKET INDEX FUND VANGUARD INDEX FUNDS 263,0842.6M $0.00 %1.16 %as of Jun 30, 2026 ↗
Fidelity Small Cap Index Fund Fidelity Salem Street Trust 216,009414.7K $0.00 %0.95 %as of Jul 31, 2026 ↗
iShares Russell 2000 Value ETF iShares Trust 153,5391.5M $0.01 %0.68 %as of Jun 30, 2026 ↗
Fidelity Extended Market Index Fund Fidelity Concord Street Trust 94,581860.7K $0.00 %0.42 %as of May 31, 2026 ↗
iShares Russell 2000 Growth ETF iShares Trust 81,441795.7K $0.01 %0.36 %as of Jun 30, 2026 ↗
iShares Micro-Cap ETF iShares Trust 66,938654K $0.04 %0.30 %as of Jun 30, 2026 ↗
Ultra-Small Company Fund Bridgeway Funds, Inc. 49,873487.3K $0.49 %0.22 %as of Jun 30, 2026 ↗
Schwab Small-Cap Index Fund SCHWAB CAPITAL TRUST 48,52093.2K $0.00 %0.21 %as of Jul 31, 2026 ↗
Master Small Cap Index Series Quantitative Master Series LLC 37,232363.8K $0.01 %0.16 %as of Jun 30, 2026 ↗
Fidelity Total Market Index Fund Fidelity Concord Street Trust 34,152310.8K $0.00 %0.15 %as of May 31, 2026 ↗
Nomura Healthcare Fund Delaware Group Equity Funds IV 33,333325.7K $0.04 %0.15 %as of Jun 30, 2026 ↗
Invesco RAFI US 1500 Small-Mid ETF Invesco Exchange-Traded Fund Trust 32,18561.8K $0.00 %0.14 %as of Jul 31, 2026 ↗
Fidelity Series Total Market Index Fund Fidelity Concord Street Trust 28,115255.8K $0.00 %0.12 %as of May 31, 2026 ↗
Nuveen Small Cap Blend Index Fund TIAA-CREF Funds 26,67651.2K $0.00 %0.12 %as of Jul 31, 2026 ↗
Fidelity Small Cap Value Index Fund Fidelity Salem Street Trust 23,571230.3K $0.01 %0.10 %as of Jun 30, 2026 ↗
Ultra-Small Company Market Fund Bridgeway Funds, Inc. 22,000214.9K $0.15 %0.10 %as of Jun 30, 2026 ↗
EQ/2000 Managed Volatility Portfolio EQ Advisors Trust 21,052205.7K $0.01 %0.09 %as of Jun 30, 2026 ↗
LVIP State Street Small-Cap Index Fund LINCOLN VARIABLE INSURANCE PRODUCTS TRUST 14,900145.6K $0.01 %0.07 %as of Jun 30, 2026 ↗
Schwab Total Stock Market Index Fund SCHWAB CAPITAL TRUST 13,40025.7K $0.00 %0.06 %as of Jul 31, 2026 ↗
T. Rowe Price Extended Equity Market Index Fund T. ROWE PRICE INDEX TRUST, INC. 10,886106.4K $0.01 %0.05 %as of Jun 30, 2026 ↗
Small Cap Index Fund Northern Funds 10,410101.7K $0.01 %0.05 %as of Jun 30, 2026 ↗
Diversified Equity Alpha Master Portfolio Master Investment Portfolio 10,259100.2K $0.00 %0.05 %as of Jun 30, 2026 ↗
Fidelity Nasdaq Composite Index Fund Fidelity Concord Street Trust 10,03391.3K $0.00 %0.04 %as of May 31, 2026 ↗
VANGUARD BALANCED INDEX FUND VANGUARD VALLEY FORGE FUNDS 10,02197.9K $0.00 %0.04 %as of Jun 30, 2026 ↗
Global X Russell 2000 ETF GLOBAL X FUNDS 9,50018.2K $0.00 %0.04 %as of Jul 31, 2026 ↗
VANGUARD INSTITUTIONAL TOTAL STOCK MARKET INDEX FUND VANGUARD INSTITUTIONAL INDEX FUNDS 8,14579.6K $0.00 %0.04 %as of Jun 30, 2026 ↗
VIP Disciplined Small Cap Portfolio Variable Insurance Products Fund II 8,05278.7K $0.01 %0.04 %as of Jun 30, 2026 ↗
MetLife Russell 2000 Index Portfolio Brighthouse Funds Trust II 6,81566.6K $0.01 %0.03 %as of Jun 30, 2026 ↗
STATE STREET SMALL/MID CAP EQUITY INDEX PORTFOLIO STATE STREET INSTITUTIONAL INVESTMENT TRUST 6,80066.4K $0.00 %0.03 %as of Jun 30, 2026 ↗
TIFF MULTI-ASSET FUND TIFF Multi-Asset Fund 5,75856.3K $0.00 %0.03 %as of Jun 30, 2026 ↗
Small-Cap Index Portfolio PACIFIC SELECT FUND 5,50553.8K $0.01 %0.02 %as of Jun 30, 2026 ↗
1290 VT Micro Cap Portfolio EQ Advisors Trust 4,51744.1K $0.02 %0.02 %as of Jun 30, 2026 ↗
ATM Small Cap Managed Volatility Portfolio EQ Advisors Trust 4,35742.6K $0.00 %0.02 %as of Jun 30, 2026 ↗
Small Cap Index Trust John Hancock Variable Insurance Trust 4,31542.2K $0.01 %0.02 %as of Jun 30, 2026 ↗
NVIT Small Cap Index Fund Nationwide Variable Insurance Trust 4,30642.1K $0.01 %0.02 %as of Jun 30, 2026 ↗
iShares Russell Small/Mid-Cap Index Fund BlackRock Funds 4,1518K $0.00 %0.02 %as of Jul 31, 2026 ↗
EQ/AB Small Cap Growth Portfolio EQ Advisors Trust 3,53034.5K $0.00 %0.02 %as of Jun 30, 2026 ↗
EQ/Small Company Index Portfolio EQ Advisors Trust 3,53034.5K $0.00 %0.02 %as of Jun 30, 2026 ↗
GuideMark Small/Mid Cap Core Fund GPS Funds I 3,40033.2K $0.03 %0.01 %as of Jun 30, 2026 ↗
Blackstone Alternative Multi-Strategy Fund Blackstone Alternative Investment Funds 3,16730.9K $0.00 %0.01 %as of Jun 30, 2026 ↗
BlackRock Advantage SMID Cap V.I. Fund BlackRock Variable Series Funds, Inc. 3,13930.7K $0.02 %0.01 %as of Jun 30, 2026 ↗
DWS Small Cap Index VIP DEUTSCHE DWS INVESTMENTS VIT FUNDS 3,11630.4K $0.01 %0.01 %as of Jun 30, 2026 ↗
T. Rowe Price Small-Cap Index Fund T. ROWE PRICE INDEX TRUST, INC. 3,00229.3K $0.01 %0.01 %as of Jun 30, 2026 ↗
Fidelity Small Cap Growth Index Fund Fidelity Salem Street Trust 2,80527.4K $0.00 %0.01 %as of Jun 30, 2026 ↗
BlackRock Small Cap Index V.I. Fund BlackRock Variable Series Funds, Inc. 2,63825.8K $0.01 %0.01 %as of Jun 30, 2026 ↗
1290 VT Small Cap Value Portfolio EQ Advisors Trust 2,56425.1K $0.01 %0.01 %as of Jun 30, 2026 ↗
T. Rowe Price Health Care ETF T. Rowe Price Exchange-Traded Funds, Inc. 2,47024.1K $0.10 %0.01 %as of Jun 30, 2026 ↗
Voya RussellTM Small Cap Index Portfolio Voya VARIABLE PORTFOLIOS INC 2,45924K $0.01 %0.01 %as of Jun 30, 2026 ↗
SA Small Cap Index Portfolio SUNAMERICA SERIES TRUST 2,3324.5K $0.00 %0.01 %as of Jul 31, 2026 ↗
Victory Extended Market Index Fund Victory Portfolios III 2,2584.3K $0.00 %0.01 %as of Jul 31, 2026 ↗
CVT Russell 2000 Small Cap Index Portfolio Calvert Variable Trust, Inc. 1,80817.7K $0.01 %0.01 %as of Jun 30, 2026 ↗
Nationwide Small Cap Index Fund Nationwide Mutual Funds 1,7343.3K $0.00 %0.01 %as of Jul 31, 2026 ↗
Venerable Small Cap Index Fund Venerable Variable Insurance Trust 1,59215.6K $0.01 %0.01 %as of Jun 30, 2026 ↗
Nationwide Fundamental All Cap Equity Portfolio Nationwide Mutual Funds 1,5613K $0.00 %0.01 %as of Jul 31, 2026 ↗
Voya VACS Index Series SC Portfolio Voya VARIABLE PORTFOLIOS INC 1,46414.3K $0.01 %0.01 %as of Jun 30, 2026 ↗
SmallCap Value Fund II Principal Funds, Inc 1,3832.7K $0.00 %0.01 %as of Jul 31, 2026 ↗
PD Small-Cap Value Index Portfolio PACIFIC SELECT FUND 1,13811.1K $0.01 %0.01 %as of Jun 30, 2026 ↗
Strategic Equity Allocation Trust John Hancock Variable Insurance Trust 9429.2K $0.00 %0.00 %as of Jun 30, 2026 ↗
EQ/Franklin Small Cap Value Managed Volatility Portfolio EQ Advisors Trust 6766.6K $0.00 %0.00 %as of Jun 30, 2026 ↗
Small-Cap Equity Portfolio PACIFIC SELECT FUND 6456.3K $0.00 %0.00 %as of Jun 30, 2026 ↗
Franklin U.S. Small Cap Multifactor Index ETF Franklin Templeton ETF Trust 6306.2K $0.01 %0.00 %as of Jun 30, 2026 ↗
Penn Series Small Cap Index Fund Penn Series Funds Inc 6005.9K $0.01 %0.00 %as of Jun 30, 2026 ↗
State Street Total Return V.I.S. Fund STATE STREET VARIABLE INSURANCE SERIES FUNDS INC 5034.9K $0.00 %0.00 %as of Jun 30, 2026 ↗
Total Stock Market Index Trust John Hancock Variable Insurance Trust 4074K $0.00 %0.00 %as of Jun 30, 2026 ↗
ULTRA SMALL CAP PROFUND ProFunds 256491.5 $0.00 %0.00 %as of Jul 31, 2026 ↗
SmallCap Growth Fund I Principal Funds, Inc 226433.9 $0.00 %as of Jul 31, 2026 ↗
Fidelity Enhanced Small Cap Growth ETF Fidelity Covington Trust 1831.8K $0.03 %0.00 %as of Jun 30, 2026 ↗
Knights of Columbus U.S. ALL CAP INDEX FUND ADVISORS' INNER CIRCLE III 126241.4 $0.00 %0.00 %as of Jul 31, 2026 ↗
Russell 2000 2x Strategy Fund Rydex Dynamic Funds 1071K $0.00 %0.00 %as of Jun 30, 2026 ↗
PROFUND VP ULTRA SMALL CAP ProFunds 82801.1 $0.00 %0.00 %as of Jun 30, 2026 ↗
PROFUND VP SMALL CAP ProFunds 53517.8 $0.00 %0.00 %as of Jun 30, 2026 ↗
Russell 2000 Fund Rydex Series Funds 49478.7 $0.00 %0.00 %as of Jun 30, 2026 ↗
Russell 2000 1.5x Strategy Fund Rydex Series Funds 29283.3 $0.00 %0.00 %as of Jun 30, 2026 ↗
Columbia Research Enhanced Small Cap ETF Columbia ETF Trust I 23224.7 $0.01 %0.00 %as of Jun 30, 2026 ↗
SMALL-CAP PROFUND ProFunds 1732.6 $0.00 %0.00 %as of Jul 31, 2026 ↗
Russell 2000(R) 1.5x Strategy Fund Rydex Variable Trust 658.6 $0.00 %0.00 %as of Jun 30, 2026 ↗

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The funds most exposed to it

The weight is the share of a fund's net assets. The holders table ranks funds by number of shares. This one ranks them by the weight of the company in each fund.

FundWeight in fund
Ultra-Small Company Fund Bridgeway Funds, Inc. 0.49 %as of Jun 30, 2026 ↗
Ultra-Small Company Market Fund Bridgeway Funds, Inc. 0.15 %as of Jun 30, 2026 ↗
T. Rowe Price Health Care ETF T. Rowe Price Exchange-Traded Funds, Inc. 0.10 %as of Jun 30, 2026 ↗
Nomura Healthcare Fund Delaware Group Equity Funds IV 0.04 %as of Jun 30, 2026 ↗
iShares Micro-Cap ETF iShares Trust 0.04 %as of Jun 30, 2026 ↗
T. Rowe Price Small-Cap Value Fund, Inc. T. ROWE PRICE SMALL-CAP VALUE FUND, INC. 0.04 %as of Jun 30, 2026 ↗
GuideMark Small/Mid Cap Core Fund GPS Funds I 0.03 %as of Jun 30, 2026 ↗
Fidelity Enhanced Small Cap Growth ETF Fidelity Covington Trust 0.03 %as of Jun 30, 2026 ↗
1290 VT Micro Cap Portfolio EQ Advisors Trust 0.02 %as of Jun 30, 2026 ↗
BlackRock Advantage SMID Cap V.I. Fund BlackRock Variable Series Funds, Inc. 0.02 %as of Jun 30, 2026 ↗

Quarter after quarter

Each row is one quarter of SEC filings, newest first. The change compares each quarter with the one before.

QuarterShareholdersChangeSharesChange
2026Q379+573,044,197+54.1 %
2026Q222+11,975,634+24.7 %
2026Q12101,583,833+63.1 %
2025Q421-3971,016-19.3 %
2025Q324-41,203,817+47.3 %
2025Q228817,267

Short sellers of KARYOPHARM THERAPEUTICS INC

Regulators publish the open short positions in this company. Titelia read them from quivad on Aug 20, 2026: today's figure

SellerPositionDisclosed on
Squarepoint Ops LLC0.5 %May 13, 2025

Institutional managers

73 managers declare this company to the SEC (Form 13F). The table shows the 25 largest.

ManagerSharesValue
Commodore Capital LP1,950,00010.9M $as of Mar 31, 2026
RA CAPITAL MANAGEMENT, L.P.1,917,35410.7M $as of Mar 31, 2026
ADAGE CAPITAL PARTNERS GP, L.L.C.1,806,32210.1M $as of Mar 31, 2026
T. Rowe Price Investment Management, Inc.1,542,0908.6K $as of Mar 31, 2026
GOLDMAN SACHS GROUP INC947,5795.3M $as of Mar 31, 2026
Catalio Capital Management, LP897,7095M $as of Mar 31, 2026
Ikarian Capital, LLC733,4354.1M $as of Mar 31, 2026
Affinity Asset Advisors, LLC500,0002.8M $as of Mar 31, 2026
Avidity Partners Management LP463,7412.6M $as of Mar 31, 2026
Soleus Capital Management, L.P.440,0002.5M $as of Mar 31, 2026
MILLENNIUM MANAGEMENT LLC420,5712.3M $as of Mar 31, 2026
Boxer Capital Management, LLC302,5361.7M $as of Mar 31, 2026
Davidson Kempner Capital Management LP300,0001.7M $as of Mar 31, 2026
ACORN CAPITAL ADVISORS, LLC287,8261.6M $as of Mar 31, 2026
Eversept Partners, LP276,1741.5M $as of Mar 31, 2026
Jump Financial, LLC262,1461.5M $as of Mar 31, 2026
Trexquant Investment LP257,9031.4M $as of Mar 31, 2026
ACADIAN ASSET MANAGEMENT LLC248,9571.4K $as of Mar 31, 2026
BlackRock, Inc.244,8991.4M $as of Mar 31, 2026
BOOTHBAY FUND MANAGEMENT, LLC213,8101.2M $as of Mar 31, 2026
Brevan Howard Capital Management LP212,3671.2M $as of Mar 31, 2026
GEODE CAPITAL MANAGEMENT, LLC206,1331.1M $as of Mar 31, 2026
UBS Group AG194,0171.1M $as of Mar 31, 2026
GROUP ONE TRADING LLC191,5271.1M $as of Mar 31, 2026
XTX Topco Ltd164,443915.9K $as of Mar 31, 2026

Declared shareholders of KARYOPHARM THERAPEUTICS INC

There are 7 beneficial ownership filings. These stakes do not add up. An asset manager that files includes its own funds, which already appear among the funds on this page.

ShareholderDeclared stakeShares
RA Capital Management, L.P. and 3 others9.90 %2,302,504as of Jun 30, 2026 · SCHEDULE 13G
Adage Capital Management, L.P. and 2 others6.78 %1,536,736as of Jun 30, 2026 · SCHEDULE 13G
THE GOLDMAN SACHS GROUP, INC. and 1 other6.30 %1,429,198as of Jun 30, 2026 · SCHEDULE 13G
ACORN BIOVENTURES, L.P. and 4 others5.70 %1,284,221as of Sep 22, 2026 · SCHEDULE 13G
Integrated Core Strategies (US) LLC and 3 others5.70 %1,297,297as of Aug 31, 2026 · SCHEDULE 13G
BlackRock, Inc. 5.60 %1,266,084as of Jun 30, 2026 · SCHEDULE 13G
Commodore Capital LP and 3 others0.00 %0as of Aug 14, 2026 · SCHEDULE 13G
Cite this page

Titelia. "Fund shareholders of KARYOPHARM THERAPEUTICS INC". https://titelia.com/en/stocks/karyopharm-therapeutics-inc-US48576U2050