| 1 | Revolution Medicines Inc | 2,375,000 | 231M $ | |
| 2 | BioMarin Pharmaceutical Inc | 3,575,000 | 202M $ | |
| 3 | Abivax SA | 1,500,000 | 167M $ | |
| 4 | Neurocrine Biosciences Inc | 1,250,000 | 164.7M $ | |
| 5 | Arrowhead Pharmaceuticals Inc | 2,275,000 | 142.6M $ | |
| 6 | Enliven Therapeutics Inc | 3,250,000 | 127.4M $ | |
| 7 | Repligen Corp | 925,000 | 109M $ | |
| 8 | Bicara Therapeutics Inc | 5,425,000 | 107.9M $ | |
| 9 | Nurix Therapeutics Inc | 6,500,000 | 100.8M $ | |
| 10 | Apogee Therapeutics Inc | 1,100,000 | 92.6M $ | |
| 11 | Ascendis Pharma A/S | 375,000 | 85.8M $ | |
| 12 | Immunocore Holdings PLC | 2,766,868 | 83.4M $ | |
| 13 | Taysha Gene Therapies Inc | 18,000,000 | 80.5M $ | |
| 14 | Dyne Therapeutics Inc | 4,000,000 | 72.5M $ | |
| 15 | Sanofi SA | 1,400,000 | 67.5M $ | |
| 16 | BioCryst Pharmaceuticals Inc | 7,025,000 | 66.9M $ | |
| 17 | Scholar Rock Holding Corp | 1,324,422 | 65.1M $ | |
| 18 | Bristol-Myers Squibb Co | 1,000,000 | 60.7M $ | |
| 19 | Monte Rosa Therapeutics Inc | 3,603,465 | 59.3M $ | |
| 20 | Vera Therapeutics Inc | 1,368,159 | 55M $ | |
| 21 | Terns Pharmaceuticals Inc | 1,000,000 | 52.7M $ | |
| 22 | Globus Medical Inc | 610,520 | 52.6M $ | |
| 23 | Boston Scientific Corp | 800,000 | 50.2M $ | |
| 24 | Nuvalent Inc | 481,715 | 49.4M $ | |
| 25 | Cogent Biosciences Inc | 1,230,888 | 47.4M $ | |
| 26 | Alto Neuroscience Inc | 2,064,075 | 46.4M $ | |
| 27 | Rapport Therapeutics Inc | 1,436,229 | 44.9M $ | |
| 28 | Disc Medicine Inc | 700,000 | 44.8M $ | |
| 29 | United Therapeutics Corp | 75,000 | 44.5M $ | |
| 30 | Celldex Therapeutics Inc | 1,224,165 | 38.8M $ | |
| 31 | KalVista Pharmaceuticals Inc | 1,850,000 | 37.2M $ | |
| 32 | Solid Biosciences Inc | 5,000,000 | 36M $ | |
| 33 | Protagonist Therapeutics Inc | 326,159 | 34.4M $ | |
| 34 | Denali Therapeutics Inc | 1,773,326 | 34M $ | |
| 35 | Regeneron Pharmaceuticals, Inc. | 40,000 | 30.9M $ | |
| 36 | Waters Corp | 100,000 | 29.8M $ | |
| 37 | Viking Therapeutics Inc | 914,147 | 29.7M $ | |
| 38 | Inspire Medical Systems Inc | 539,269 | 27.8M $ | |
| 39 | Trevi Therapeutics Inc | 2,166,504 | 25.8M $ | |
| 40 | Lexeo Therapeutics Inc | 4,475,000 | 25.7M $ | |
| 41 | Soleno Therapeutics Inc | 730,000 | 24.4M $ | |
| 42 | Beta Bionics Inc | 2,211,518 | 22.2M $ | |
| 43 | Nektar Therapeutics | 285,000 | 20.5M $ | |
| 44 | Cytokinetics Inc | 300,000 | 19.8M $ | |
| 45 | West Pharmaceutical Services Inc | 75,000 | 18.8M $ | |
| 46 | GE HealthCare Technologies Inc | 250,000 | 17.8M $ | |
| 47 | SpyGlass Pharma Inc | 666,760 | 17.3M $ | |
| 48 | Zimmer Biomet Holdings Inc | 190,000 | 17.2M $ | |
| 49 | Madrigal Pharmaceuticals Inc | 31,468 | 16.5M $ | |
| 50 | GeneDx Holdings Corp | 250,000 | 16.1M $ | |
| 51 | DAMORA THERAPEUTICS INC | 600,000 | 15.5M $ | |
| 52 | Agios Pharmaceuticals Inc | 450,000 | 15.2M $ | |
| 53 | Savara Inc | 2,600,052 | 14.2M $ | |
| 54 | Tarsus Pharmaceuticals Inc | 200,000 | 14M $ | |
| 55 | Voyager Therapeutics Inc | 3,002,936 | 11.6M $ | |
| 56 | Insulet Corp | 50,601 | 10.6M $ | |
| 57 | Tectonic Therapeutic Inc | 328,000 | 10.1M $ | |
| 58 | Surrozen Inc | 338,611 | 9.9M $ | |
| 59 | Arvinas Inc | 905,465 | 9.6M $ | |
| 60 | MapLight Therapeutics Inc | 420,000 | 8.5M $ | |
| 61 | Fulcrum Therapeutics Inc | 1,100,000 | 8.4M $ | |
| 62 | OnKure Therapeutics Inc | 1,839,819 | 7.6M $ | |
| 63 | Myriad Genetics Inc | 1,648,000 | 7.4M $ | |
| 64 | Olema Pharmaceuticals Inc | 428,551 | 6.4M $ | |
| 65 | Anteris Technologies Global Corp | 1,144,780 | 6.4M $ | |
| 66 | Candel Therapeutics Inc | 1,125,000 | 5.5M $ | |
| 67 | Palisade Bio Inc | 2,500,000 | 4.4M $ | |
| 68 | Veracyte Inc | 130,687 | 4.2M $ | |
| 69 | ZENAS BIOPHARMA INC | 200,000 | 3.9M $ | |
| 70 | Geron Corp | 2,540,000 | 3.8M $ | |
| 71 | Monopar Therapeutics Inc | 65,418 | 3.6M $ | |
| 72 | Passage Bio Inc | 305,000 | 2.4M $ | |
| 73 | Tyra Biosciences Inc | 54,000 | 2.1M $ | |
| 74 | REGENXBIO Inc | 108,525 | 909.4K $ | |
| 75 | Tenax Therapeutics Inc | 53,439 | 854.5K $ | |
| 76 | MacroGenics Inc | 280,000 | 809.2K $ | |
| 77 | Absci Corp | 232,219 | 696.7K $ | |
| 78 | APREA THERAPEUTICS INC | 350,000 | 267K $ | |