Holdings of Janus Henderson Global Life Sciences Fund
JANUS INVESTMENT FUND · 76 declared positions · as of Mar 31, 2026
Original filing · Net assets 5.2B $ · Ten largest lines: 45 % of the equity sleeve
Sector breakdown
- Health care 65.2 %
- Unattributed 34.8 %
Sector is not declared in Form N-PORT: this is a Titelia classification, decided company by company. The unattributed share is counted as such rather than spread over the others.
Currency breakdown
- USD 91.3 %
- GBP 5.2 %
- EUR 3.0 %
- JPY 0.4 %
The currency each line is denominated in, as declared. It does not follow the country: a French company listed in the United States is declared in dollars.
Country breakdown
- US 90.5 %
- GB 5.2 %
- FR 2.4 %
- BE 0.7 %
- CA 0.4 %
- VG 0.4 %
- JP 0.4 %
Shares computed on the equity sleeve, the only part this site carries.
| Country | Lines | Value | Share |
|---|---|---|---|
| US | 70 | 4.1B $ | 90.47 % |
| GB | 1 | 238.6M $ | 5.22 % |
| FR | 1 | 107.7M $ | 2.36 % |
| BE | 1 | 31.5M $ | 0.69 % |
| CA | 1 | 20.3M $ | 0.44 % |
| VG | 1 | 18.8M $ | 0.41 % |
| JP | 1 | 18.5M $ | 0.40 % |
Positions
| Company | Shares | Value | Weight |
|---|---|---|---|
| Eli Lilly & Co | 499,479 | 459.4M $ | 8.84 % |
| Johnson & Johnson | 1,550,240 | 378.9M $ | 7.29 % |
| AstraZeneca PLC | 1,221,946 | 238.6M $ | 4.59 % |
| AbbVie Inc | 967,983 | 210.5M $ | 4.05 % |
| UnitedHealth Group Inc | 601,241 | 162.7M $ | 3.13 % |
| Thermo Fisher Scientific Inc | 265,275 | 130.4M $ | 2.51 % |
| Praxis Precision Medicines Inc | 394,970 | 127.3M $ | 2.45 % |
| Abbott Laboratories | 1,212,497 | 124.5M $ | 2.40 % |
| Bridgebio Pharma Inc | 1,551,141 | 115.2M $ | 2.22 % |
| Sanofi SA | 1,116,972 | 107.7M $ | 2.07 % |
| Vertex Pharmaceuticals Inc | 239,922 | 107.1M $ | 2.06 % |
| Revolution Medicines Inc | 1,088,018 | 105.8M $ | 2.04 % |
| Intuitive Surgical Inc | 227,319 | 104.8M $ | 2.02 % |
| HCA Healthcare Inc | 206,592 | 97.8M $ | 1.88 % |
| Boston Scientific Corp | 1,520,117 | 95.4M $ | 1.84 % |
| Amgen Inc | 270,089 | 95M $ | 1.83 % |
| Stryker Corp | 260,843 | 85.7M $ | 1.65 % |
| Danaher Corp | 448,567 | 85M $ | 1.64 % |
| Madrigal Pharmaceuticals Inc | 149,195 | 78.1M $ | 1.50 % |
| CVS Health Corp | 1,071,894 | 77M $ | 1.48 % |
| Merck & Co Inc | 638,574 | 76.8M $ | 1.48 % |
| PTC Therapeutics Inc | 1,024,173 | 69.8M $ | 1.34 % |
| United Therapeutics Corp | 116,721 | 69.2M $ | 1.33 % |
| McKesson Corp | 79,818 | 69.1M $ | 1.33 % |
| Gilead Sciences Inc | 471,681 | 65.7M $ | 1.26 % |
| Globus Medical Inc | 748,604 | 64.5M $ | 1.24 % |
| Mirum Pharmaceuticals Inc | 685,482 | 63.3M $ | 1.22 % |
| Vaxcyte Inc | 971,737 | 56.5M $ | 1.09 % |
| Medtronic PLC | 583,432 | 50.6M $ | 0.97 % |
| Elevance Health Inc | 165,285 | 48.4M $ | 0.93 % |
| Dyne Therapeutics Inc | 2,528,224 | 45.8M $ | 0.88 % |
| Cencora Inc | 139,138 | 43.7M $ | 0.84 % |
| Travere Therapeutics Inc | 1,432,164 | 42.5M $ | 0.82 % |
| Lantheus Holdings Inc | 518,786 | 39.3M $ | 0.76 % |
| Medline Inc | 864,511 | 38.5M $ | 0.74 % |
| Edwards Lifesciences Corp | 465,579 | 37.3M $ | 0.72 % |
| Dexcom Inc | 561,491 | 35.3M $ | 0.68 % |
| Soleno Therapeutics Inc | 987,780 | 33.1M $ | 0.64 % |
| Apogee Therapeutics Inc | 379,608 | 32M $ | 0.61 % |
| UCB SA | 104,561 | 31.5M $ | 0.61 % |
| Becton Dickinson & Co | 181,577 | 28.5M $ | 0.55 % |
| Glaukos Corp | 264,704 | 28.5M $ | 0.55 % |
| Ideaya Biosciences Inc | 738,748 | 24.6M $ | 0.47 % |
| Penumbra Inc | 73,736 | 24.2M $ | 0.47 % |
| Tarsus Pharmaceuticals Inc | 296,425 | 20.8M $ | 0.40 % |
| Edgewise Therapeutics Inc | 659,507 | 20.8M $ | 0.40 % |
| Xenon Pharmaceuticals Inc | 348,546 | 20.3M $ | 0.39 % |
| Cooper Cos Inc/The | 281,740 | 20.1M $ | 0.39 % |
| Cogent Biosciences Inc | 498,576 | 19.2M $ | 0.37 % |
| Biohaven Ltd | 2,220,238 | 18.8M $ | 0.36 % |
| Regeneron Pharmaceuticals, Inc. | 23,991 | 18.5M $ | 0.36 % |
| Daiichi Sankyo Co Ltd | 1,047,000 | 18.5M $ | 0.36 % |
| STERIS PLC | 81,916 | 18.1M $ | 0.35 % |
| Neurocrine Biosciences Inc | 136,901 | 18M $ | 0.35 % |
| Protagonist Therapeutics Inc | 160,299 | 16.9M $ | 0.33 % |
| Scholar Rock Holding Corp | 341,699 | 16.8M $ | 0.32 % |
| Zoetis Inc | 131,945 | 15.6M $ | 0.30 % |
| Ardelyx Inc | 2,595,821 | 15.5M $ | 0.30 % |
| Alnylam Pharmaceuticals Inc | 45,992 | 15.2M $ | 0.29 % |
| Sotera Health Co | 1,058,022 | 15.2M $ | 0.29 % |
| Crinetics Pharmaceuticals Inc | 394,286 | 14.3M $ | 0.28 % |
| HeartFlow Inc | 585,648 | 14.2M $ | 0.27 % |
| Rhythm Pharmaceuticals Inc | 160,804 | 14M $ | 0.27 % |
| Nuvalent Inc | 128,313 | 13.1M $ | 0.25 % |
| Illumina Inc | 102,214 | 12.6M $ | 0.24 % |
| Insulet Corp | 59,223 | 12.4M $ | 0.24 % |
| Teleflex Inc | 97,944 | 11.7M $ | 0.23 % |
| Mirum Pharmaceuticals Inc | 123,782 | 11.4M $ | 0.22 % |
| Centene Corp | 340,855 | 11.2M $ | 0.21 % |
| Janux Therapeutics Inc | 720,074 | 10M $ | 0.19 % |
| Olema Pharmaceuticals Inc | 669,297 | 10M $ | 0.19 % |
| Terns Pharmaceuticals Inc | 187,062 | 9.9M $ | 0.19 % |
| Humana Inc | 52,740 | 9.1M $ | 0.18 % |
| Immunome Inc | 368,708 | 8.1M $ | 0.16 % |
| 4D Molecular Therapeutics Inc | 843,751 | 7.9M $ | 0.15 % |
| Lexeo Therapeutics Inc | 633,486 | 3.6M $ | 0.07 % |