Funds holding Orchestra BioMed Holdings Inc
ISIN US68572M1062 · United States
- Fund holders
- 64
- Of which ETFs
- 9 55 other funds
- Value held
- 23.5M $
- Share of capital
- 9.3 % of 60.1M shares on Aug 6, 2026
| Fund | Shares | Value | Weight in fund | Share of capital | |
|---|---|---|---|---|---|
| VANGUARD TOTAL STOCK MARKET INDEX FUND VANGUARD INDEX FUNDS | 1,470,063 | 6.3M $ | 0.00 % | 2.45 % | as of Jun 30, 2026 ↗ |
| iShares Russell 2000 ETF iShares Trust | 830,752 | 3.6M $ | 0.00 % | 1.38 % | as of Jun 30, 2026 ↗ |
| VANGUARD EXTENDED MARKET INDEX FUND VANGUARD INDEX FUNDS | 498,632 | 2.2M $ | 0.00 % | 0.83 % | as of Jun 30, 2026 ↗ |
| Fidelity Small Cap Index Fund Fidelity Salem Street Trust | 428,758 | 1.7M $ | 0.01 % | 0.71 % | as of Jul 31, 2026 ↗ |
| iShares Russell 2000 Growth ETF iShares Trust | 374,286 | 1.6M $ | 0.01 % | 0.62 % | as of Jun 30, 2026 ↗ |
| Simplify Propel Opportunities ETF Simplify Exchange Traded Funds | 219,387 | 946.7K $ | 1.23 % | 0.37 % | as of Jun 30, 2026 ↗ |
| BlackRock Health Sciences Opportunities Portfolio BlackRock Funds | 206,130 | 806K $ | 0.01 % | 0.34 % | as of May 29, 2026 ↗ |
| Fidelity Extended Market Index Fund Fidelity Concord Street Trust | 205,715 | 804.3K $ | 0.00 % | 0.34 % | as of May 31, 2026 ↗ |
| Schwab U.S. Small-Cap ETF SCHWAB STRATEGIC TRUST | 178,322 | 697.2K $ | 0.00 % | 0.30 % | as of May 31, 2026 ↗ |
| iShares Micro-Cap ETF iShares Trust | 133,768 | 577.2K $ | 0.04 % | 0.22 % | as of Jun 30, 2026 ↗ |
| Schwab Small-Cap Index Fund SCHWAB CAPITAL TRUST | 97,254 | 387.1K $ | 0.01 % | 0.16 % | as of Jul 31, 2026 ↗ |
| Clearwater Select Equity Fund Clearwater Investment Trust | 86,424 | 372.9K $ | 0.07 % | 0.14 % | as of Jun 30, 2026 ↗ |
| Master Small Cap Index Series Quantitative Master Series LLC | 74,501 | 321.5K $ | 0.01 % | 0.12 % | as of Jun 30, 2026 ↗ |
| Ultra-Small Company Market Fund Bridgeway Funds, Inc. | 73,500 | 317.2K $ | 0.21 % | 0.12 % | as of Jun 30, 2026 ↗ |
| Fidelity Total Market Index Fund Fidelity Concord Street Trust | 72,838 | 284.8K $ | 0.00 % | 0.12 % | as of May 31, 2026 ↗ |
| Fidelity Series Total Market Index Fund Fidelity Concord Street Trust | 59,022 | 230.8K $ | 0.00 % | 0.10 % | as of May 31, 2026 ↗ |
| Nuveen Small Cap Blend Index Fund TIAA-CREF Funds | 52,118 | 207.4K $ | 0.01 % | 0.09 % | as of Jul 31, 2026 ↗ |
| Fidelity Nasdaq Composite Index Fund Fidelity Concord Street Trust | 45,456 | 177.7K $ | 0.00 % | 0.08 % | as of May 31, 2026 ↗ |
| Schwab U.S. Broad Market ETF SCHWAB STRATEGIC TRUST | 43,636 | 170.6K $ | 0.00 % | 0.07 % | as of May 31, 2026 ↗ |
| EQ/2000 Managed Volatility Portfolio EQ Advisors Trust | 41,425 | 178.7K $ | 0.00 % | 0.07 % | as of Jun 30, 2026 ↗ |
| Schwab Total Stock Market Index Fund SCHWAB CAPITAL TRUST | 40,496 | 161.2K $ | 0.00 % | 0.07 % | as of Jul 31, 2026 ↗ |
| Fidelity Small Cap Growth Index Fund Fidelity Salem Street Trust | 37,226 | 160.6K $ | 0.01 % | 0.06 % | as of Jun 30, 2026 ↗ |
| LVIP State Street Small-Cap Index Fund LINCOLN VARIABLE INSURANCE PRODUCTS TRUST | 30,300 | 130.7K $ | 0.01 % | 0.05 % | as of Jun 30, 2026 ↗ |
| VANGUARD INSTITUTIONAL TOTAL STOCK MARKET INDEX FUND VANGUARD INSTITUTIONAL INDEX FUNDS | 27,315 | 117.9K $ | 0.00 % | 0.05 % | as of Jun 30, 2026 ↗ |
| VANGUARD BALANCED INDEX FUND VANGUARD VALLEY FORGE FUNDS | 26,906 | 116.1K $ | 0.00 % | 0.04 % | as of Jun 30, 2026 ↗ |
| Goldman Sachs Absolute Return Tracker Fund GOLDMAN SACHS TRUST | 20,207 | 87.2K $ | 0.00 % | 0.03 % | as of Jun 30, 2026 ↗ |
| Global X Russell 2000 ETF GLOBAL X FUNDS | 19,057 | 75.8K $ | 0.01 % | 0.03 % | as of Jul 31, 2026 ↗ |
| Small Cap Index Fund Northern Funds | 18,442 | 79.6K $ | 0.00 % | 0.03 % | as of Jun 30, 2026 ↗ |
| MetLife Russell 2000 Index Portfolio Brighthouse Funds Trust II | 14,648 | 63.2K $ | 0.01 % | 0.02 % | as of Jun 30, 2026 ↗ |
| Health Sciences Portfolio PACIFIC SELECT FUND | 12,512 | 54K $ | 0.01 % | 0.02 % | as of Jun 30, 2026 ↗ |
| Small-Cap Index Portfolio PACIFIC SELECT FUND | 10,963 | 47.3K $ | 0.01 % | 0.02 % | as of Jun 30, 2026 ↗ |
| iShares Russell Small/Mid-Cap Index Fund BlackRock Funds | 9,914 | 39.5K $ | 0.00 % | 0.02 % | as of Jul 31, 2026 ↗ |
| Small Cap Core Fund Northern Funds | 9,620 | 41.5K $ | 0.01 % | 0.02 % | as of Jun 30, 2026 ↗ |
| 1290 VT Micro Cap Portfolio EQ Advisors Trust | 9,028 | 39K $ | 0.02 % | 0.02 % | as of Jun 30, 2026 ↗ |
| ATM Small Cap Managed Volatility Portfolio EQ Advisors Trust | 8,710 | 37.6K $ | 0.00 % | 0.01 % | as of Jun 30, 2026 ↗ |
| NVIT Small Cap Index Fund Nationwide Variable Insurance Trust | 8,505 | 36.7K $ | 0.01 % | 0.01 % | as of Jun 30, 2026 ↗ |
| DWS Small Cap Index VIP DEUTSCHE DWS INVESTMENTS VIT FUNDS | 6,295 | 27.2K $ | 0.01 % | 0.01 % | as of Jun 30, 2026 ↗ |
| EQ/Morgan Stanley Small Cap Growth Portfolio EQ Advisors Trust | 6,056 | 26.1K $ | 0.01 % | 0.01 % | as of Jun 30, 2026 ↗ |
| T. Rowe Price Small-Cap Index Fund T. ROWE PRICE INDEX TRUST, INC. | 6,009 | 25.9K $ | 0.01 % | 0.01 % | as of Jun 30, 2026 ↗ |
| BlackRock Small Cap Index V.I. Fund BlackRock Variable Series Funds, Inc. | 5,157 | 22.3K $ | 0.01 % | 0.01 % | as of Jun 30, 2026 ↗ |
| GuideMark Small/Mid Cap Core Fund GPS Funds I | 4,956 | 21.4K $ | 0.02 % | 0.01 % | as of Jun 30, 2026 ↗ |
| SA Small Cap Index Portfolio SUNAMERICA SERIES TRUST | 4,667 | 18.6K $ | 0.01 % | 0.01 % | as of Jul 31, 2026 ↗ |
| PD Small-Cap Growth Index Portfolio PACIFIC SELECT FUND | 3,693 | 15.9K $ | 0.01 % | 0.01 % | as of Jun 30, 2026 ↗ |
| CVT Russell 2000 Small Cap Index Portfolio Calvert Variable Trust, Inc. | 3,617 | 15.6K $ | 0.01 % | 0.01 % | as of Jun 30, 2026 ↗ |
| Nationwide Small Cap Index Fund Nationwide Mutual Funds | 3,455 | 13.8K $ | 0.01 % | 0.01 % | as of Jul 31, 2026 ↗ |
| Venerable Small Cap Index Fund Venerable Variable Insurance Trust | 3,187 | 13.8K $ | 0.01 % | 0.01 % | as of Jun 30, 2026 ↗ |
| Avantis U.S. Small Cap Equity ETF American Century ETF Trust | 3,182 | 12.4K $ | 0.00 % | 0.01 % | as of May 31, 2026 ↗ |
| SmallCap Growth Fund I Principal Funds, Inc | 3,048 | 12.1K $ | 0.00 % | 0.01 % | as of Jul 31, 2026 ↗ |
| Invesco Nasdaq Biotechnology ETF Invesco Exchange-Traded Fund Trust II | 2,983 | 11.7K $ | 0.02 % | 0.00 % | as of May 31, 2026 ↗ |
| EQ/AB Small Cap Growth Portfolio EQ Advisors Trust | 2,300 | 9.9K $ | 0.00 % | 0.00 % | as of Jun 30, 2026 ↗ |
| EQ/Small Company Index Portfolio EQ Advisors Trust | 2,300 | 9.9K $ | 0.00 % | 0.00 % | as of Jun 30, 2026 ↗ |
| ProShares Ultra Nasdaq Biotechnology ProShares Trust | 2,089 | 8.2K $ | 0.01 % | 0.00 % | as of May 31, 2026 ↗ |
| EQ/Franklin Small Cap Value Managed Volatility Portfolio EQ Advisors Trust | 1,351 | 5.8K $ | 0.00 % | 0.00 % | as of Jun 30, 2026 ↗ |
| Penn Series Small Cap Index Fund Penn Series Funds Inc | 1,200 | 5.2K $ | 0.01 % | 0.00 % | as of Jun 30, 2026 ↗ |
| State Street Total Return V.I.S. Fund STATE STREET VARIABLE INSURANCE SERIES FUNDS INC | 1,006 | 4.3K $ | 0.00 % | 0.00 % | as of Jun 30, 2026 ↗ |
| ULTRA SMALL CAP PROFUND ProFunds | 513 | 2K $ | 0.00 % | 0.00 % | as of Jul 31, 2026 ↗ |
| Knights of Columbus U.S. ALL CAP INDEX FUND ADVISORS' INNER CIRCLE III | 262 | 1K $ | 0.00 % | 0.00 % | as of Jul 31, 2026 ↗ |
| Russell 2000 2x Strategy Fund Rydex Dynamic Funds | 214 | 923.4 $ | 0.00 % | 0.00 % | as of Jun 30, 2026 ↗ |
| PROFUND VP ULTRA SMALL CAP ProFunds | 164 | 707.7 $ | 0.00 % | 0.00 % | as of Jun 30, 2026 ↗ |
| PROFUND VP SMALL CAP ProFunds | 107 | 461.7 $ | 0.00 % | 0.00 % | as of Jun 30, 2026 ↗ |
| Russell 2000 Fund Rydex Series Funds | 99 | 427.2 $ | 0.00 % | 0.00 % | as of Jun 30, 2026 ↗ |
| Russell 2000 1.5x Strategy Fund Rydex Series Funds | 59 | 254.6 $ | 0.00 % | 0.00 % | as of Jun 30, 2026 ↗ |
| SMALL-CAP PROFUND ProFunds | 34 | 135.3 $ | 0.00 % | 0.00 % | as of Jul 31, 2026 ↗ |
| Russell 2000(R) 1.5x Strategy Fund Rydex Variable Trust | 11 | 47.5 $ | 0.00 % | 0.00 % | as of Jun 30, 2026 ↗ |
The funds most exposed to it
The weight is the share of a fund's net assets. The holders table ranks funds by number of shares. This one ranks them by the weight of the company in each fund.
| Fund | Weight in fund | |
|---|---|---|
| Simplify Propel Opportunities ETF Simplify Exchange Traded Funds | 1.23 % | as of Jun 30, 2026 ↗ |
| Ultra-Small Company Market Fund Bridgeway Funds, Inc. | 0.21 % | as of Jun 30, 2026 ↗ |
| Clearwater Select Equity Fund Clearwater Investment Trust | 0.07 % | as of Jun 30, 2026 ↗ |
| iShares Micro-Cap ETF iShares Trust | 0.04 % | as of Jun 30, 2026 ↗ |
| GuideMark Small/Mid Cap Core Fund GPS Funds I | 0.02 % | as of Jun 30, 2026 ↗ |
| 1290 VT Micro Cap Portfolio EQ Advisors Trust | 0.02 % | as of Jun 30, 2026 ↗ |
| Invesco Nasdaq Biotechnology ETF Invesco Exchange-Traded Fund Trust II | 0.02 % | as of May 31, 2026 ↗ |
| Health Sciences Portfolio PACIFIC SELECT FUND | 0.01 % | as of Jun 30, 2026 ↗ |
| BlackRock Health Sciences Opportunities Portfolio BlackRock Funds | 0.01 % | as of May 29, 2026 ↗ |
| ProShares Ultra Nasdaq Biotechnology ProShares Trust | 0.01 % | as of May 31, 2026 ↗ |
Quarter after quarter
Each row is one quarter of SEC filings, newest first. The change compares each quarter with the one before.
| Quarter | Holders | Change | Shares | Change |
|---|---|---|---|---|
| 2026Q3 | 64 | +39 | 5,563,850 | +59.1 % |
| 2026Q2 | 25 | +2 | 3,497,818 | +33.2 % |
| 2026Q1 | 23 | -2 | 2,626,674 | +11.8 % |
| 2025Q4 | 25 | -14 | 2,349,370 | -4.0 % |
| 2025Q3 | 39 | -52 | 2,446,443 | -35.0 % |
| 2025Q2 | 91 | +4 | 3,762,462 | -0.1 % |
| 2025Q1 | 87 | +4 | 3,765,885 | +0.5 % |
| 2024Q4 | 83 | +7 | 3,745,794 | +13.7 % |
| 2024Q3 | 76 | -1 | 3,294,788 | +4.0 % |
| 2024Q2 | 77 | +3 | 3,168,819 | -1.8 % |
| 2024Q1 | 74 | 0 | 3,227,537 | +10.7 % |
| 2023Q4 | 74 | 2,914,323 |
Institutional managers
62 managers declare this company to the SEC (Form 13F). The table shows the 25 largest.
| Manager | Shares | Value | |
|---|---|---|---|
| RTW INVESTMENTS, LP | 8,306,063 | 35.3M $ | as of Mar 31, 2026 |
| PERCEPTIVE ADVISORS LLC | 5,037,906 | 21.4M $ | as of Mar 31, 2026 |
| Alyeska Investment Group, L.P. | 1,000,000 | 4.3M $ | as of Mar 31, 2026 |
| Propel Bio Management, LLC | 896,701 | 3.8M $ | as of Mar 31, 2026 |
| MILLENNIUM MANAGEMENT LLC | 702,543 | 3M $ | as of Mar 31, 2026 |
| BlackRock, Inc. | 635,714 | 2.7M $ | as of Mar 31, 2026 |
| GEODE CAPITAL MANAGEMENT, LLC | 485,492 | 2.1M $ | as of Mar 31, 2026 |
| Affinity Asset Advisors, LLC | 402,550 | 1.7M $ | as of Mar 31, 2026 |
| CHARLES SCHWAB INVESTMENT MANAGEMENT INC | 265,499 | 1.1M $ | as of Mar 31, 2026 |
| Knott David M Jr | 253,651 | 1.1M $ | as of Mar 31, 2026 |
| Simplify Asset Management Inc. | 219,387 | 932.4K $ | as of Mar 31, 2026 |
| MARSHALL WACE, LLP | 188,484 | 801.1K $ | as of Mar 31, 2026 |
| 683 Capital Management, LLC | 185,000 | 786.3K $ | as of Mar 31, 2026 |
| STATE STREET CORP | 169,410 | 720K $ | as of Mar 31, 2026 |
| GOLDMAN SACHS GROUP INC | 155,242 | 659.8K $ | as of Mar 31, 2026 |
| DAFNA Capital Management LLC | 126,841 | 539.1K $ | as of Mar 31, 2026 |
| NORTHERN TRUST CORP | 118,274 | 502.7K $ | as of Mar 31, 2026 |
| Qube Research & Technologies Ltd | 108,953 | 463.1K $ | as of Mar 31, 2026 |
| IFP Advisors, Inc | 98,887 | 420.3K $ | as of Mar 31, 2026 |
| SUSQUEHANNA INTERNATIONAL GROUP, LLP | 97,521 | 414.5K $ | as of Mar 31, 2026 |
| Point72 Asset Management, L.P. | 87,888 | 373.5K $ | as of Mar 31, 2026 |
| CITADEL ADVISORS LLC | 79,185 | 336.5K $ | as of Mar 31, 2026 |
| Hudson Bay Capital Management LP | 71,134 | 302.3K $ | as of Mar 31, 2026 |
| RENAISSANCE TECHNOLOGIES LLC | 70,900 | 301.3K $ | as of Mar 31, 2026 |
| BRIDGEWAY CAPITAL MANAGEMENT, LLC | 70,600 | 300.1K $ | as of Mar 31, 2026 |
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