| 1 | Vertex Pharmaceuticals Inc | 681,908 | 304.5M $ | |
| 2 | Argenx SE | 313,000 | 228.6M $ | |
| 3 | Regeneron Pharmaceuticals, Inc. | 278,674 | 215.3M $ | |
| 4 | Scholar Rock Holding Corp | 3,584,573 | 176.2M $ | |
| 5 | Gilead Sciences Inc | 1,169,879 | 163M $ | |
| 6 | Revolution Medicines Inc | 1,544,456 | 150.2M $ | |
| 7 | Ionis Pharmaceuticals Inc | 1,818,665 | 136.6M $ | |
| 8 | Intuitive Surgical Inc | 286,654 | 132.1M $ | |
| 9 | Viridian Therapeutics Inc | 6,726,144 | 131.6M $ | |
| 10 | Krystal Biotech Inc | 481,785 | 124.5M $ | |
| 11 | Crinetics Pharmaceuticals Inc | 3,280,000 | 119.1M $ | |
| 12 | Abbott Laboratories | 1,151,635 | 118.2M $ | |
| 13 | Nuvalent Inc | 1,053,268 | 107.9M $ | |
| 14 | Amgen Inc | 295,358 | 103.9M $ | |
| 15 | Boston Scientific Corp | 1,466,894 | 92M $ | |
| 16 | Enliven Therapeutics Inc | 2,320,867 | 91M $ | |
| 17 | Immunocore Holdings PLC | 2,796,803 | 84.3M $ | |
| 18 | Alnylam Pharmaceuticals Inc | 234,543 | 77.6M $ | |
| 19 | Relay Therapeutics Inc | 7,795,242 | 77.6M $ | |
| 20 | Stryker Corp | 217,237 | 71.4M $ | |
| 21 | Vaxcyte Inc | 1,190,697 | 69.2M $ | |
| 22 | Vera Therapeutics Inc | 1,710,771 | 68.8M $ | |
| 23 | Edwards Lifesciences Corp | 839,451 | 67.2M $ | |
| 24 | DAMORA THERAPEUTICS INC | 2,298,000 | 59.5M $ | |
| 25 | Tango Therapeutics Inc | 2,400,000 | 50.2M $ | |
| 26 | IDEXX Laboratories Inc | 89,131 | 50.1M $ | |
| 27 | Ultragenyx Pharmaceutical Inc | 2,380,000 | 49.9M $ | |
| 28 | Dexcom Inc | 788,766 | 49.5M $ | |
| 29 | JADE BIOSCIENCES INC | 3,501,502 | 49.2M $ | |
| 30 | Edgewise Therapeutics Inc | 1,528,518 | 48.1M $ | |
| 31 | UnitedHealth Group Inc | 148,203 | 40.1M $ | |
| 32 | Danaher Corp | 202,164 | 38.3M $ | |
| 33 | Celldex Therapeutics Inc | 1,200,000 | 38.1M $ | |
| 34 | ResMed Inc | 159,346 | 35.8M $ | |
| 35 | Insulet Corp | 163,656 | 34.3M $ | |
| 36 | Thermo Fisher Scientific Inc | 64,412 | 31.7M $ | |
| 37 | Eli Lilly & Co | 33,932 | 31.2M $ | |
| 38 | GE HealthCare Technologies Inc | 416,887 | 29.7M $ | |
| 39 | Disc Medicine Inc | 459,314 | 29.4M $ | |
| 40 | Johnson & Johnson | 119,102 | 29.1M $ | |
| 41 | Annexon Inc | 5,157,290 | 28.6M $ | |
| 42 | Cigna Group/The | 98,263 | 26.2M $ | |
| 43 | Oruka Therapeutics Inc | 507,008 | 24.9M $ | |
| 44 | Merck & Co Inc | 206,591 | 24.9M $ | |
| 45 | Align Technology Inc | 139,680 | 23.9M $ | |
| 46 | Globus Medical Inc | 247,261 | 21.3M $ | |
| 47 | Monte Rosa Therapeutics Inc | 1,250,000 | 20.6M $ | |
| 48 | AbbVie Inc | 93,567 | 20.3M $ | |
| 49 | Cooper Cos Inc/The | 272,184 | 19.5M $ | |
| 50 | McKesson Corp | 22,352 | 19.3M $ | |
| 51 | Becton Dickinson & Co | 121,887 | 19.2M $ | |
| 52 | HCA Healthcare Inc | 37,765 | 17.9M $ | |
| 53 | Glaukos Corp | 145,703 | 15.7M $ | |
| 54 | Elevance Health Inc | 52,518 | 15.4M $ | |
| 55 | Zimmer Biomet Holdings Inc | 155,571 | 14.1M $ | |
| 56 | PROCEPT BIOROBOTICS CORP | 502,286 | 12.6M $ | |
| 57 | Humana Inc | 64,498 | 11.2M $ | |
| 58 | TransMedics Group Inc | 101,139 | 10.1M $ | |
| 59 | Veeva Systems Inc | 56,517 | 9.9M $ | |
| 60 | Centene Corp | 261,066 | 8.5M $ | |
| 61 | Teva Pharmaceutical Industries Ltd | 250,082 | 7.5M $ | |
| 62 | Tenet Healthcare Corp | 38,269 | 7.2M $ | |
| 63 | 10X Genomics Inc | 329,492 | 7M $ | |
| 64 | CVS Health Corp | 89,363 | 6.4M $ | |
| 65 | Natera Inc | 31,694 | 6.3M $ | |
| 66 | Waystar Holding Corp | 256,139 | 6.2M $ | |
| 67 | Medline Inc | 136,635 | 6.1M $ | |
| 68 | Inspire Medical Systems Inc | 99,735 | 5.1M $ | |
| 69 | Privia Health Group Inc | 226,703 | 4.7M $ | |
| 70 | Penumbra Inc | 12,267 | 4M $ | |
| 71 | Atrium Therapeutics Inc | 263,096 | 3.5M $ | |
| 72 | Pfizer Inc | 107,635 | 3M $ | |
| 73 | Illumina Inc | 20,223 | 2.5M $ | |
| 74 | Omada Health Inc | 157,938 | 2M $ | |
| 75 | Bridgebio Pharma Inc | 25,377 | 1.9M $ | |
| 76 | BioNTech SE | 20,851 | 1.9M $ | |
| 77 | State Street SPDR S&P 500 ETF Trust | 2,700 | 1.8M $ | |
| 78 | Insmed Inc | 10,034 | 1.6M $ | |
| 79 | Madrigal Pharmaceuticals Inc | 3,040 | 1.6M $ | |
| 80 | Masimo Corp | 8,753 | 1.6M $ | |
| 81 | Protagonist Therapeutics Inc | 14,447 | 1.5M $ | |
| 82 | United Therapeutics Corp | 2,077 | 1.2M $ | |
| 83 | BEONE MEDICINES LTD | 3,812 | 1.1M $ | |
| 84 | Phreesia Inc | 130,992 | 1.1M $ | |
| 85 | Adaptive Biotechnologies Corp | 76,181 | 1.1M $ | |
| 86 | Bristol-Myers Squibb Co | 17,038 | 1M $ | |
| 87 | Encompass Health Corp | 9,829 | 950.8K $ | |
| 88 | Apple Inc | 3,320 | 842.6K $ | |
| 89 | Billiontoone Inc | 10,554 | 833.1K $ | |
| 90 | Mineralys Therapeutics Inc | 29,374 | 795.7K $ | |
| 91 | Equinor ASA | 17,573 | 741.6K $ | |
| 92 | Exxon Mobil Corp | 4,370 | 741.4K $ | |
| 93 | BP PLC | 15,644 | 735.3K $ | |
| 94 | Shell PLC | 7,844 | 729.5K $ | |
| 95 | Beta Bionics Inc | 72,152 | 723K $ | |
| 96 | Biogen Inc | 3,653 | 669.7K $ | |
| 97 | LEGEND BIOTECH CORP | 35,886 | 649.2K $ | |
| 98 | Cisco Systems, Inc. | 8,000 | 620.7K $ | |
| 99 | Neurocrine Biosciences Inc | 4,646 | 612.1K $ | |
| 100 | Alibaba Group Holding Ltd | 4,700 | 589.7K $ | |