Holdings of Palo Alto Investors LP
44 declared positions · as of Mar 31, 2026
Original filing · Ten largest lines: 68 % of the equity sleeve
Sector breakdown
- Health care 21.9 %
- Unattributed 78.1 %
Titelia classification, company by company. The unattributed share stays visible.
Currency breakdown
The quoted currency of each line, as declared.
Country breakdown
- US 99.5 %
- DE 0.3 %
- GB 0.3 %
Shares computed on the equity sleeve.
| Country | Lines | Value | Share |
|---|
| US | 41 | 610.6M $ | 99.46 % |
| DE | 1 | 1.7M $ | 0.28 % |
| GB | 2 | 1.6M $ | 0.26 % |
Positions
| Company | Shares | Value | Weight |
|---|
| Insmed Inc | 415,269 | 67.9M $ | |
| ACADIA Pharmaceuticals Inc | 2,872,695 | 63.9M $ | |
| PTC Therapeutics Inc | 921,607 | 62.8M $ | |
| BioMarin Pharmaceutical Inc | 685,182 | 38.7M $ | |
| United Therapeutics Corp | 62,809 | 37.2M $ | |
| AnaptysBio Inc | 638,161 | 35.4M $ | |
| Mirum Pharmaceuticals Inc | 325,175 | 30M $ | |
| Dyne Therapeutics Inc | 1,652,972 | 30M $ | |
| Biogen Inc | 140,719 | 25.8M $ | |
| Disc Medicine Inc | 401,719 | 25.7M $ | |
| Iovance Biotherapeutics Inc | 6,349,563 | 22.3M $ | |
| Syndax Pharmaceuticals Inc | 864,986 | 20.2M $ | |
| Annexon Inc | 2,948,090 | 16.3M $ | |
| Amicus Therapeutics Inc | 1,113,045 | 16.1M $ | |
| Ultragenyx Pharmaceutical Inc | 596,495 | 12.5M $ | |
| Bicara Therapeutics Inc | 550,408 | 10.9M $ | |
| Celldex Therapeutics Inc | 296,408 | 9.4M $ | |
| CareDx Inc | 531,870 | 9.2M $ | |
| Compass Therapeutics Inc | 1,514,504 | 8M $ | |
| Agios Pharmaceuticals Inc | 213,601 | 7.2M $ | |
| Align Technology Inc | 41,520 | 7.1M $ | |
| Capricor Therapeutics Inc | 229,763 | 7M $ | |
| Travere Therapeutics Inc | 230,453 | 6.8M $ | |
| Taysha Gene Therapies Inc | 1,391,382 | 6.2M $ | |
| Aclaris Therapeutics Inc | 1,613,430 | 6.1M $ | |
| Denali Therapeutics Inc | 234,582 | 4.5M $ | |
| Oruka Therapeutics Inc | 59,985 | 2.9M $ | |
| Stoke Therapeutics Inc | 84,631 | 2.8M $ | |
| Edwards Lifesciences Corp | 33,640 | 2.7M $ | |
| Neurocrine Biosciences Inc | 18,117 | 2.4M $ | |
| Nuvation Bio Inc | 508,846 | 2.2M $ | |
| Cytokinetics Inc | 32,195 | 2.1M $ | |
| eHealth Inc | 1,482,797 | 1.9M $ | |
| BioNTech SE | 19,614 | 1.7M $ | |
| Pyxis Oncology Inc | 1,010,510 | 1.5M $ | |
| Verastem Inc | 246,093 | 1.3M $ | |
| Bicycle Therapeutics PLC | 201,890 | 936.8K $ | |
| Madrigal Pharmaceuticals Inc | 1,787 | 935.4K $ | |
| Humana Inc | 3,985 | 691K $ | |
| Compass Pathways plc | 115,616 | 639.4K $ | |
| Xeris Biopharma Holdings Inc | 104,410 | 605.6K $ | |
| Abeona Therapeutics Inc | 108,865 | 487.7K $ | |
| Inspire Medical Systems Inc | 8,772 | 452.5K $ | |
| Aldeyra Therapeutics Inc | 155,709 | 263.1K $ | |