{
	"fund": "First Trust NYSE Arca Biotechnology Index Fund",
	"id": "S000012478",
	"url": "https://titelia.com/en/funds/S000012478",
	"manager": "First Trust Exchange-Traded Fund",
	"filing": "sec",
	"currency": "USD",
	"net_assets": 2812691023.18,
	"as_of": "2026-06-30",
	"page": {
		"total": 30,
		"limit": 1000,
		"offset": 0,
		"more": false,
		"next": null,
		"previous": null
	},
	"holdings": [
		{
			"isin": "US2183521028",
			"company": "Corcept Therapeutics Inc",
			"company_url": "https://titelia.com/en/stocks/corcept-therapeutics-inc-US2183521028",
			"country": "US",
			"shares": 1810937,
			"value": 157460972.15,
			"currency": "USD",
			"weight": 5.5982,
			"as_of": "2026-06-30"
		},
		{
			"isin": "US64049M2098",
			"company": "NeoGenomics Inc",
			"company_url": "https://titelia.com/en/stocks/neogenomics-inc-US64049M2098",
			"country": "US",
			"shares": 9869496,
			"value": 143995946.64,
			"currency": "USD",
			"weight": 5.1195,
			"as_of": "2026-06-30"
		},
		{
			"isin": "US92337F1075",
			"company": "Veracyte Inc",
			"company_url": "https://titelia.com/en/stocks/veracyte-inc-US92337F1075",
			"country": "US",
			"shares": 2441185,
			"value": 143370795.05,
			"currency": "USD",
			"weight": 5.0973,
			"as_of": "2026-06-30"
		},
		{
			"isin": "US1167941087",
			"company": "Bruker Corp",
			"company_url": "https://titelia.com/en/stocks/bruker-corp-US1167941087",
			"country": "US",
			"shares": 2019057,
			"value": 121506850.26,
			"currency": "USD",
			"weight": 4.32,
			"as_of": "2026-06-30"
		},
		{
			"isin": "IE00B56GVS15",
			"company": "Alkermes PLC",
			"company_url": "https://titelia.com/en/stocks/alkermes-plc-IE00B56GVS15",
			"country": "IE",
			"shares": 2275074,
			"value": 119202502.23,
			"currency": "USD",
			"weight": 4.238,
			"as_of": "2026-06-30"
		},
		{
			"isin": "US4523271090",
			"company": "Illumina Inc",
			"company_url": "https://titelia.com/en/stocks/illumina-inc-US4523271090",
			"country": "US",
			"shares": 627605,
			"value": 110351787.15,
			"currency": "USD",
			"weight": 3.9234,
			"as_of": "2026-06-30"
		},
		{
			"isin": "US5011471027",
			"company": "Krystal Biotech Inc",
			"company_url": "https://titelia.com/en/stocks/krystal-biotech-inc-US5011471027",
			"country": "US",
			"shares": 293036,
			"value": 108912690.12,
			"currency": "USD",
			"weight": 3.8722,
			"as_of": "2026-06-30"
		},
		{
			"isin": "US6323071042",
			"company": "NATERA INC",
			"company_url": "https://titelia.com/en/stocks/natera-inc-US6323071042",
			"country": "US",
			"shares": 393185,
			"value": 106730068.25,
			"currency": "USD",
			"weight": 3.7946,
			"as_of": "2026-06-30"
		},
		{
			"isin": "US05464T1043",
			"company": "Axsome Therapeutics Inc",
			"company_url": "https://titelia.com/en/stocks/axsome-therapeutics-inc-US05464T1043",
			"country": "US",
			"shares": 426122,
			"value": 104301881.94,
			"currency": "USD",
			"weight": 3.7083,
			"as_of": "2026-06-30"
		},
		{
			"isin": "US64125C1099",
			"company": "Neurocrine Biosciences Inc",
			"company_url": "https://titelia.com/en/stocks/neurocrine-biosciences-inc-US64125C1099",
			"country": "US",
			"shares": 588847,
			"value": 99241329.15,
			"currency": "USD",
			"weight": 3.5283,
			"as_of": "2026-06-30"
		},
		{
			"isin": "US09073M1045",
			"company": "Bio-Techne Corp",
			"company_url": "https://titelia.com/en/stocks/bio-techne-corp-US09073M1045",
			"country": "US",
			"shares": 1366518,
			"value": 96544496.7,
			"currency": "USD",
			"weight": 3.4325,
			"as_of": "2026-06-30"
		},
		{
			"isin": "US04280A1007",
			"company": "Arrowhead Pharmaceuticals Inc",
			"company_url": "https://titelia.com/en/stocks/arrowhead-pharmaceuticals-inc-US04280A1007",
			"country": "US",
			"shares": 1165127,
			"value": 94969501.77,
			"currency": "USD",
			"weight": 3.3765,
			"as_of": "2026-06-30"
		},
		{
			"isin": "US09062X1037",
			"company": "Biogen Inc",
			"company_url": "https://titelia.com/en/stocks/biogen-inc-US09062X1037",
			"country": "US",
			"shares": 438784,
			"value": 94803671.04,
			"currency": "USD",
			"weight": 3.3706,
			"as_of": "2026-06-30"
		},
		{
			"isin": "US30161Q1040",
			"company": "Exelixis Inc",
			"company_url": "https://titelia.com/en/stocks/exelixis-inc-US30161Q1040",
			"country": "US",
			"shares": 1714400,
			"value": 93280504,
			"currency": "USD",
			"weight": 3.3164,
			"as_of": "2026-06-30"
		},
		{
			"isin": "US45337C1027",
			"company": "Incyte Corp",
			"company_url": "https://titelia.com/en/stocks/incyte-corp-US45337C1027",
			"country": "US",
			"shares": 790013,
			"value": 89555873.68,
			"currency": "USD",
			"weight": 3.184,
			"as_of": "2026-06-30"
		},
		{
			"isin": "US04016X1019",
			"company": "Argenx SE",
			"company_url": "https://titelia.com/en/stocks/argenx-se-US04016X1019",
			"country": "NL",
			"shares": 94913,
			"value": 88057434.01,
			"currency": "USD",
			"weight": 3.1307,
			"as_of": "2026-06-30"
		},
		{
			"isin": "US40637H1095",
			"company": "Halozyme Therapeutics Inc",
			"company_url": "https://titelia.com/en/stocks/halozyme-therapeutics-inc-US40637H1095",
			"country": "US",
			"shares": 1119086,
			"value": 87590861.22,
			"currency": "USD",
			"weight": 3.1141,
			"as_of": "2026-06-30"
		},
		{
			"isin": "US92532F1003",
			"company": "Vertex Pharmaceuticals Inc",
			"company_url": "https://titelia.com/en/stocks/vertex-pharmaceuticals-inc-US92532F1003",
			"country": "US",
			"shares": 173968,
			"value": 86415124.64,
			"currency": "USD",
			"weight": 3.0723,
			"as_of": "2026-06-30"
		},
		{
			"isin": "US7599161095",
			"company": "Repligen Corp",
			"company_url": "https://titelia.com/en/stocks/repligen-corp-US7599161095",
			"country": "US",
			"shares": 631943,
			"value": 86222302.92,
			"currency": "USD",
			"weight": 3.0655,
			"as_of": "2026-06-30"
		},
		{
			"isin": "US09061G1013",
			"company": "BioMarin Pharmaceutical Inc",
			"company_url": "https://titelia.com/en/stocks/biomarin-pharmaceutical-inc-US09061G1013",
			"country": "US",
			"shares": 1391830,
			"value": 79640512.6,
			"currency": "USD",
			"weight": 2.8315,
			"as_of": "2026-06-30"
		},
		{
			"isin": "US0311621009",
			"company": "Amgen Inc",
			"company_url": "https://titelia.com/en/stocks/amgen-inc-US0311621009",
			"country": "US",
			"shares": 216227,
			"value": 78300121.24,
			"currency": "USD",
			"weight": 2.7838,
			"as_of": "2026-06-30"
		},
		{
			"isin": "US09075V1026",
			"company": "BioNTech SE",
			"company_url": "https://titelia.com/en/stocks/biontech-se-US09075V1026",
			"country": "DE",
			"shares": 794727,
			"value": 73949347.35,
			"currency": "USD",
			"weight": 2.6291,
			"as_of": "2026-06-30"
		},
		{
			"isin": "US3723032062",
			"company": "Genmab A/S",
			"company_url": "https://titelia.com/en/stocks/genmab-a-s-US3723032062",
			"country": "DK",
			"shares": 2686600,
			"value": 73800902,
			"currency": "USD",
			"weight": 2.6239,
			"as_of": "2026-06-30"
		},
		{
			"isin": "US91307C1027",
			"company": "United Therapeutics Corp",
			"company_url": "https://titelia.com/en/stocks/united-therapeutics-corp-US91307C1027",
			"country": "US",
			"shares": 132748,
			"value": 71926848.84,
			"currency": "USD",
			"weight": 2.5572,
			"as_of": "2026-06-30"
		},
		{
			"isin": "US02043Q1076",
			"company": "ALNYLAM PHARMACEUTICALS INC",
			"company_url": "https://titelia.com/en/stocks/alnylam-pharmaceuticals-inc-US02043Q1076",
			"country": "US",
			"shares": 235602,
			"value": 70923270.06,
			"currency": "USD",
			"weight": 2.5215,
			"as_of": "2026-06-30"
		},
		{
			"isin": "US07725L1026",
			"company": "BEONE MEDICINES LTD",
			"company_url": "https://titelia.com/en/stocks/beone-medicines-ltd-US07725L1026",
			"country": "US",
			"shares": 245095,
			"value": 69844722.15,
			"currency": "USD",
			"weight": 2.4832,
			"as_of": "2026-06-30"
		},
		{
			"isin": "US3755581036",
			"company": "Gilead Sciences Inc",
			"company_url": "https://titelia.com/en/stocks/gilead-sciences-inc-US3755581036",
			"country": "US",
			"shares": 545899,
			"value": 68968879.66,
			"currency": "USD",
			"weight": 2.4521,
			"as_of": "2026-06-30"
		},
		{
			"isin": "US0008991046",
			"company": "ADMA Biologics Inc",
			"company_url": "https://titelia.com/en/stocks/adma-biologics-inc-US0008991046",
			"country": "US",
			"shares": 7823567,
			"value": 65483255.79,
			"currency": "USD",
			"weight": 2.3281,
			"as_of": "2026-06-30"
		},
		{
			"isin": "US8036071004",
			"company": "SAREPTA THERAPEUTICS INC",
			"company_url": "https://titelia.com/en/stocks/sarepta-therapeutics-inc-US8036071004",
			"country": "US",
			"shares": 3583400,
			"value": 64393698,
			"currency": "USD",
			"weight": 2.2894,
			"as_of": "2026-06-30"
		},
		{
			"isin": "US75886F1075",
			"company": "Regeneron Pharmaceuticals Inc",
			"company_url": "https://titelia.com/en/stocks/regeneron-pharmaceuticals-inc-US75886F1075",
			"country": "US",
			"shares": 101350,
			"value": 63195779,
			"currency": "USD",
			"weight": 2.2468,
			"as_of": "2026-06-30"
		}
	],
	"source": "Public filings of the fund regulators, republished by titelia",
	"served_by": {
		"name": "titelia",
		"url": "https://titelia.com/en/api"
	},
	"terms": "https://titelia.com/en/mentions",
	"documentation": "https://titelia.com/en/api"
}
